China
Africa
Explore chapters and articles related to this topic
Water Pollution and Medicinal Plants
Published in Azamal Husen, Environmental Pollution and Medicinal Plants, 2022
Antul Kumar, Anuj Choudhary, Harmanjot Kaur, Ritesh Kumar, Radhika Sharma, Himani Gautam, Sahil Mehta
The 3.9-fold increased silver nanoparticles can be correlated with the uplift amount of hydrogen peroxide, catalase activity, lipid peroxidation levels, and other signalling molecule production in Arabidopsis. The exposure of cadmium oxide was proved to be responsible for the increment in the content of isovitexin and ferulic acid. In Prunella vulgaris, callus tissue of such important antiviral properties containing herb grown in silver and naphthalene acetic acid (NAA), similar findings of high accumulation of flavonoids and phenolics along with the maximum growth in callus induction were reported (Fazal et al. 2016). Another medicinal plant, Matricaria chamomilla, was grown for ten days in different concentrations of copper solution (Kováčik et al. 2008). A total of 11 secondary metabolites were examined, including caffeic, salicylic acid, chlorogenic, o-coumaric acid, sinapic, protocatechuic, vanillic, p-hydroxybenzoic, gentisic, and syringic acid obtained from methanolic extract (Kováčik et al. 2008).
Greece and Rome
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
Theophrastus wrote that mandrake (Mandragora officinalis, an anodyne and soporific known to the Biblical writers of the Old Testament as the love apple) was suitable for use as an aphrodisiac. Several kinds of a plant known as all-heal (Prunella vulgaris, an astringent, and tonic; Valeriana officinalis, an analgesic and sedative; and Stachys palustris, an antispasmodic and antiseptic) were thought useful in a pessary for miscarriage. The roots of the plants were used during labor and for other ‘diseases of women’. Root of cyclamen (sowbread, Cyclamen hederaefolium of the Primulaceae family, containing a saponin-like drug known as cyclamin) was used to induce rapid delivery and as a love-potion.
Increasing the Sensitivity of Adipocytes and Skeletal Muscle Cells to Insulin
Published in Christophe Wiart, Medicinal Plants in Asia for Metabolic Syndrome, 2017
Oleanolic acid, ursone, 2α,3α-dihydroxylurs-12-en-28-oic acid, 2α,3β-dihydroxyolean-12-en-28-oic acid, 2α,3α-24-trihydroxyurs-12-en-28-oic acid, 2α,3α-24-trihydroxyolean-12-en-28-oic acid, 2α,3α-24-trihydroxyurs-12,20(30)-dien-28-oic acid, 2α,3β, 19α-trihydroxyurs-12-en-28-oic acid and 2α,3α, 24-trihydroxyurs-12-en-28-oic acid-28-β-d-glucopyranoside isolated from the spikes of Prunella vulgaris L. inhibited the enzymatic activity of rabbit muscle glycogen phosphorylase with IC50 values below 70 μM (positive standard caffeine: IC50 value 74.5 μM).308 In 3T3-L1 differentiated adipocytes, oleanolic acid, 2α,3β-dihydroxyolean-12-en-28-oic acid, 2α,3α-24-trihydroxyurs-12-en-28-oic acid, and 2α,3α, 24-trihydroxyurs-12-en-28-oic acid-28-β-d-glucopyranoside at a concentration of 10 μM enhanced insulin-induced glucose consumption.308 2α,3α,24-Trihydroxyurs-12-en-28-oic acid at 10 μM was as efficient as metformin at a concentration of 1 mM.308
Biosynthesis of antioxidative enzymes and polyphenolics content in calli cultures of Prunella vulgaris L. in response to auxins and cytokinins
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2020
Hina Fazal, Bilal Haider Abbasi, Nisar Ahmad, Bushra Noureen, Jahangir Shah, Dan Ma, Liu Chuanliang, Fazal Akbar, Muhammad Nazir Uddin, Haji Khan, Mohammad Ali
Prunella vulgaris L. is perennial, edible and wound healing plant from Lamiaceae family. Ustakhudus is its traditional name, but due to its wound healing properties, it is also known by ‘self-heal and all-heal’. This plant was traditionally utilised by various tribes for the treatment of various ailments since unknown time in countries including North America, China and Europe [1,2]. Numerous studies revealed that P. vulgaris have a broad spectrum of therapeutic potentials, which include antiseptic, anti-cancerous, antispasmodic, antirhematic and anti-HSV etc. [3,4]. Some reports showed that it is used to treat sore throat, inflammations, pains, fevers and also useful in decreasing high blood pressure [5]. Recent studies conducted by many scientists suggest that this herb is very potentials against Human immune virus and Herpes viruses [6]. The biological activities of P. vulgaris are because of the presence of many active phytochemicals. Recently its demand for therapeutic industries is higher than its production. But interestingly, lesser information on its synthesis under field and in vitro environments is available. For the synthesis of consistent plantlets and active secondary metabolites, this therapeutically significant herb needs reliable techniques.
Sustainable production of biomass and industrially important secondary metabolites in cell cultures of selfheal (Prunella vulgaris L.) elicited by silver and gold nanoparticles
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2019
Hina Fazal, Bilal Haider Abbasi, Nisar Ahmad, Mohammad Ali, Syed Shujait Ali, Abbas Khan, Dong-Qing Wei
Prunella vulgaris (self heal/all heal) is thermophilic and hygrophilous edible herb (family; Lamiaceae), that has been utilized in North America, China and Europe as a potent herbal medicine [7]. Recent studies emphasized on the potentials of P. vulgaris as promising anti-HIV and against herpes viruses [7]. However, in Unani, Korean and Chinese traditional medicine, it has been widely used against cold and sore throat, headache, oedema goiter and nephritis [8–10]. Due to the occurrence of polyphenols in this plant species, it also exhibits properties including, antitumor, antiviral and anti-inflammatory [11,12]. Plant-based phenolic and flavonoids, and their various activities are associated with antioxidant potential [13]. During extreme conditions, like light fluctuation, osmotic stress and in defense mechanism against injury, the plant antioxidant system plays a protective role against these conditions. DPPH-based antioxidant activity or others have a direct or linear relationship with species resistance toward the stressors [14–16].
Cardioprotective effect of rosmarinic acid against myocardial ischaemia/reperfusion injury via suppression of the NF-κB inflammatory signalling pathway and ROS production in mice
Published in Pharmaceutical Biology, 2021
Wei Quan, Hui-xian Liu, Wei Zhang, Wei-juan Lou, Yang-ze Gong, Chong Yuan, Qing Shao, Na Wang, Chao Guo, Fei Liu
RosA is a natural, water-soluble phenolic acid compound that can be isolated from Rosmarinus officinalis L. (Labiatae). Due to its widespread distribution, it is particularly found in plants of Lamiaceae and Boraginaceae in large amounts. RosA also serves as an effective active ingredient of Salvia miltiorrhiza Bge., Perilla frutescens (L.) Britt., Prunella vulgaris L. and other Chinese herbal medicines (Cai et al. 2019). Moreover, it possesses oxidation resistance (Zych et al. 2019), anti-inflammation (Fan et al. 2015), immune regulation (Cao et al. 2019) and anti-thrombosis (Zou et al. 1993) activities and other biological functions. Studies have found that RosA can help prevent cell damage caused by free radicals due to its strong antioxidant activity, which is related to its structure (Fujimoto et al. 2010). The catechol hydroxyl eliminates free radical activity, while its C-3 conjugated double bond has a synergistic effect (Imai et al. 2019). According to numerous investigations, oxidative stress is the most serious and long-lasting factor that leads to myocardial I/R injury (Gonzalez-Montero et al. 2018). Therefore, it is believed that RosA is a likely drug candidate for preventing and treating heart and cerebrovascular diseases. Previous studies have also reported that RosA has protective effects against acute ischaemic injury (Ramalho et al. 2014) and hypoxia/reoxygenation myocardial cell injury in rats (Zhang et al. 2017). Furthermore, recent studies have shown that RosA has strong anti-apoptotic ability and can protect cells from hydrogen peroxide-induced DNA damage and apoptosis (Salimei et al. 2007). In light of the above studies, this investigation assumed that RosA possesses protective effects in myocardial ischaemia/reperfusion injury.