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Fatigue
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
You may find that taking one or two capsules of digestive enzymes 30 minutes before eating or with your meal helps with digestive issues. Also, there are natural digestive enzymes that aid in digestion such as pineapples, papayas, mangoes, and honey, as well as fermented foods like kefir, sauerkraut, and kimchi. In Ayurvedic medicine, it is not uncommon to begin the meal with a small glass of bitters to help your stomach release more gastric juices and prepare for digestion.
Value-Added Products and Bioactive Compounds from Fruit Wastes
Published in Megh R. Goyal, Arijit Nath, Rasul Hafiz Ansar Suleria, Plant-Based Functional Foods and Phytochemicals, 2021
Ranjay Kumar Thakur, Rahel Suchintita Das, Prashant K. Biswas, Mukesh Singh
The pineapple by-products also contain a significant amount of dietary fiber, mainly insoluble dietary fiber, and can be used for the development of food-grade low-calorie fiber-enriched food products [68]. Crown of pineapple was used as the carbon source for the media for the growth of three different strains, namely, Rhodopseudomonas Saccharomyces cerevisiae (baker’s yeast), and Trichoderma harzianum. These strains were used for microbial single-cell protein production [118].
Sweeteners
Published in Christopher Cumo, Ancestral Diets and Nutrition, 2020
Chapter 3 contrasted animals, which store most surplus energy as fat, with plants, which store excess as carbohydrates, whether starch, sugars, or both. Because of this ability, many plants have some sucrose. For example, 100 grams of mangos (Mangifera indica) have 7 grams of sucrose.30 Sucrose, fructose, and glucose impart sweetness to pineapples (Ananas comosus), apricots (Prunus armeniaca), dates, figs (Ficus carica), and many other dessert fruits. Although less sweet, vegetables and legumes may also have sucrose. For example, despite dissimilar flavors, identical amounts of pineapples and peas have the same quantity of sucrose.31 Of the global florae, two plants—sugarcane (Saccharum officinarum) and sugar beet (Beta vulgaris ssp. vulgaris)—feed the world’s sucrose addiction.
A comprehensive overview on the anti-inflammatory, antitumor, and ferroptosis functions of bromelain: an emerging cysteine protease
Published in Expert Opinion on Biological Therapy, 2022
Prajitha K Rajan, Nageswara Rao Dunna, Sivaramakrishnan Venkatabalasubramanian
Furthermore, the optimum pH for stem BRL activity is 7, whereas fruit BRL is functional at a divergent pH range of 3–8. In addition, both fruit and stem BRL go through complicated glycosylation depending on enzyme availability, amino acid sequence, and protein shape. The current glycosylation status of stem and fruit BRL requires further extensive research and is still nascent. The other two significant enzymes present in pineapple are ananain, with molecular mass and isoelectric point the same as stem BRL. Comosain is the other endopeptidase with 24,400 Da molecular mass, 186 amino acids, and possesses glycosylation [7,8]. BRL possesses many therapeutic properties like anti-inflammatory, anti-thrombotic, and fibrinolytic activity. Besides these, studies have also proven the anticancer activity and its ability to promote apoptotic cell death. Multi-organ failure caused by distinct inflammation and systemic coagulation initiated by viral components of SAR-COV-2 accounts for challenges and increasing mortality. A recent finding has proven the potential anti-inflammatory and anti-coagulant properties of BRL as a therapeutic adjuvant for alleviating the inflammation associated with the SARS-CoV-2 virus and reducing its progression [9].
Green isolation and physical modification of pineapple stem waste starch as pharmaceutical excipient
Published in Drug Development and Industrial Pharmacy, 2019
Annisa Rahma, Melissa Adriani, Puji Rahayu, Raymond R. Tjandrawinata, Heni Rachmawati
Pineapple stem waste has been utilized as a source of chemicals including ehthanol, citric acid, hydrogen gas, antidying agent, antioxidant compound, antimicrobial compound, and bromelain [3]. Pineapple stem waste has been known mainly as a source of bromelain, a protein-digesting enzyme. Isolation of bromelain from pineapple stem has been reported in a number of studies [3–5]. After bromelain extraction from pineapple stem waste, more than 98% of the residue can be utilized [5]. In addition to bromelain, pineapple stem also contains starch, a material that has drawn considerable interest in pharmaceutical formulation. Furthermore, similar to bromelain, the starch in pineapple plant is mainly deposited within the stem [6]. Since bromelain and starch are both used in pharmaceutical dosage form, the waste management can be more efficient. However, pineapple stem starch is still under-explored. Nakhtong et al. [7] has reported physical characteristics of native pineapple stem starch, including gelatinization behavior and pasting properties. Until recently, pineapple stem starch has not been explored in solid drug dosage forms.
Bromelain plus peroxidase reduces non-Hodgkin lymphoma progression in invivo via up-regulation of antioxidant enzymes and modulating apoptotic protein expression
Published in Nutrition and Cancer, 2020
Rahul Debnath, Debabrata Majumder, Priyatosh Nath, Durgadas Ghosh, Debasish Maiti
Development of cancer is one of the critical and multistep processes which involved mutation in genetic code, abnormal gene regulation, environmental factors like exposure of different carcinogenic agents, etc. The risk of cancer is increased with age. Different kinds of anticancer drugs are available in the markets for cancer patients. They are given to the individual in combination of more than one chemotherapeutic drug like 5-florouracil, etc. (21). But these drugs have several side effects in the patient’s body and destroy the normal cells. Different types of plant based materials like flavonoids and different enzymes play an important role in cancer by preventing DNA damage and by increasing the antioxidant level in human body with much lesser amount of side effects (22). Recently different types of phytochemical compounds isolated from different plant parts are used in vitro and in vivo to prevent different types of disease like cancer. Pineapple is one of the common edible tropical fruit which contains different types of important enzymes. Bromelain, a protease enzyme present in pineapple. Pineapple juice contain other different types of enzymes along with bromelain, like peroxidase, polyphenol oxidase, etc. and it is established that bromelain have anticancer activity against different cancers. But there is less reports are available that the activity of bromelain along with peroxidase from pineapple juice against T-cell lymphoma. In our previous report we also found that, acetone precipitation of pineapple extract contains bromelain along with peroxidase which was confirmed by Sodium dodecyl sulfate-polyacrylamide gel electrophoresis method (15).