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Apiaceae Plants Growing in the East
Published in Mahendra Rai, Shandesh Bhattarai, Chistiane M. Feitosa, Ethnopharmacology of Wild Plants, 2021
Sherweit El-Ahmady, Nehal Ibrahim, Nermeen Farag, Sara Gabr
Petroselinum (parsley) is a genus of two species of flowering plants: Petroselinum crispum (garden parsley) and P. segetum (corn parsley). The widely cultivated P. crispum (parsley or garden parsley) is an important culinary herb, widely used as a flavoring agent and as a vegetable. It is native to the central Mediterranean region (Cyprus, southern Italy, Greece, Portugal, Spain, Malta, Morocco, Algeria, and Tunisia), but has naturalized elsewhere in Europe and planted throughout the world due to its usage in the food industry and pharmaceutical, cosmetic and perfume manufacturing. There are two main cultivated varieties of parsley plants used as herbs in recipes: P. crispum var. neapolitanum, and P. crispum var. crispum, the latter is also known as curled-leaf parsley (French parsley), while P. crispum var. neapolitanum is flat-leafed (Italian) parsley. Flat-leaf Italian parsley is more closely related to the wild parsley species that was first grown in the Mediterranean. Compared to curly parsley, flat-leafed parsley is generally harder, has a stronger flavor and is easier to grow. However, some people prefer the curly-leaf variety because of its decorative appearance in garnishing. Both parsley types taste very similar and both offer similar health benefits (Herbst 2001).
Byzantium
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
John Lindley in his Flora Medica (1838) wrote that parsley leaves acted as a diuretic (by inference also as an emmenagogue, as both properties were thought similar) and that ‘the fruit is a deadly poison to parrots’. Parsley root was still advised as a treatment for functional amenorrhea in the British Herbal Pharmacopoeia of 1991 (p. 155). Parsley contains apiole and myristicin which have diuretic properties. The volatile oil of parsley is a strong uterine stimulant.
Nutraceuticals for Hypertension Control
Published in Nilanjana Maulik, Personalized Nutrition as Medical Therapy for High-Risk Diseases, 2020
Balázs Varga, Mariann Bombicz, Andrea Kurucz, Béla Juhász
In folk medicine parsley has been used as a remedy for its powerful diuretic effect. Several studies ascribe additional hypotensive properties to the plant which could be considered a consequence of its diuretic effect (Farzaei, Abbasabadi et al. 2013). Kreydiyyeh and Usta (2002) investigated this evidence and aimed to uncover its underlying mechanism. Rats treated with aqueous parsley seed extract eliminated a significantly larger volume of urine as compared to the control group. These finding were supported by an in situ kidney perfusion technique with similar results as well. According to this, they assume that the diuretic effect of extract is mediated through an increase in K+ retention in the lumen. In conclusion, the mechanism of action of parsley seems to be mediated through an inhibition of the Na+–K+ pump that would lead to a decrease in Na+ and K+ reabsorption leading thus to an osmotic water flow into the lumen, and diuresis (Kreydiyyeh and Usta 2002).
The predictive utility of the plant phylogeny in identifying sources of cardiovascular drugs
Published in Pharmaceutical Biology, 2018
Emily Guzman, Jeanmaire Molina
Experimental studies have repeatedly shown that members of the family Apiaceae work as diuretics. Diuretics increase urine output and lower blood pressure by inhibiting the reabsorption of sodium at different parts of the renal tubular system (Klabunde 2012). Ammi visnaga has been used traditionally in Egypt to treat kidney stones (Vanachayangkul et al. 2010), and has been demonstrated to possess potent diuretic activity due to its bioactive component khellin (Khan et al. 2001; Günaydin and Beyazit 2004). The confamilial Angelica dahurica, an important medicinal plant in the Far East, has also been traditionally used as diuretic (Sarker and Nahar 2004). In celery, Apium graveolens, diuresis due to its constituent, n-butylphthalide, promoted its antihypertensive effect (Moghadam et al. 2013). The crude extract of coriander, Coriandrum sativum, similarly worked as a diuretic in an experiment in rats (Jabeen et al. 2009). In parsley, Petroselinum crispum, phenolic compounds, flavonoids and essential oil components are believed to be responsible for many of its pharmacological activities including its diuretic and antiplatelet activity (Farzaei et al. 2013). Though there were no experimental studies found to support Daucus carota’s (carrot) or Ligusticim wallichii’s use as a diuretic, it is predicted that based on this phylogenetic pattern for Apiaceae, that these species may also promote diuresis.
Biological Markers of Oxidative Stress in Cardiovascular Diseases: After so Many Studies, What do We Know?
Published in Immunological Investigations, 2018
Josef Fontana, Michal Zima, Vaclav Vetvicka
Using a similar experimental design of cisplatin-induced cardiotoxicity in rats, Abdellatief et al. (2017) found an increase in oxidative stress markers and a decrease in the activities of antioxidant enzymes. An oral administration of parsley oil reversed these effects. Similarly, geraniol oil alleviated diabetic cardiac complication, probably via its suppression of oxidative stress (El-Bassossy et al., 2017). Natural polyphenol zingerone, known for its antioxidant properties, offered cardioprotective effects through amelioration of oxidative stress shown by strong decrease in MDA levels and lowering glutathione and catalase activity (Soliman et al., 2018).
Anticancer Effect in Human Glioblastoma and Antioxidant Activity of Petroselinum crispum L. Methanol Extract
Published in Nutrition and Cancer, 2021
Nadhem Aissani, Ferdaous Albouchi, Hichem Sebai
Petroselinum crispum, commonly known as parsley belonging to the Apiaceae family, is native to Mediterranean countries. The fresh or dried leaves of parsley are widely employed as spice, garnish and flavoring ingredient. It is also frequently used in different regions of the word as gastrotonic, diuretic, antiseptic of urinary tract, anti-urolithiasis, anti-dote, and anti-inflammatory (9,10).