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Nutritional and Dietary Supplementation during Pregnancy
Published in “Bert” Bertis Britt Little, Drugs and Pregnancy, 2022
Mineral oil is a lubricant laxative. There are no published human epidemiological or animal teratology studies with this agent. However, chronic use of mineral oil as a laxative might interfere with the absorption of fat-soluble vitamins such as vitamin K and D, and thus theoretically could have adverse fetal effects.
Acne, rosacea, and similar disorders
Published in Rashmi Sarkar, Anupam Das, Sumit Sethi, Concise Dermatology, 2021
Some cosmetics contain comedo-inducing (comedogenic) agents, such as cocoa butter, isopropylmyristate, derivatives and some mineral oils, which can induce acne. With the availability of less comedogenic cosmetics, its prevalence has lessened. Use of thick, oil-based hair products contributes to acne development on the forehead, which is termed as pomade acne.
Chronic Idiopathic Constipation
Published in Kevin W. Olden, Handbook of Functional Gastrointestinal Disorders, 2020
Osmotic Agents Of the many laxatives available, lactulose or sorbitol is recommended for chronic use if fiber supplements are ineffective or poorly tolerated (66). The effective daily dose ranges from 7.5 to 30 ml. Polyethylene glycol electrolyte solution (8 to 16 oz per day) may be effective as well, although published studies are methodologically flawed (67). Mineral oil should be avoided because it may lead to aspiration with lipid pneumonia and perhaps to deficiencies of fat-soluble vitamins.
Emerging drugs for the treatment of epidermolysis bullosa
Published in Expert Opinion on Emerging Drugs, 2020
Matthias Titeux, Mathilde Bonnet des Claustres, Araksya Izmiryan, Helene Ragot, Alain Hovnanian
Gastrointestinal tract complications are most commonly seen in RDEB but can also be present in EBS and JEB subtypes. They contribute to nutritional compromise. Painful dysphagia resulting from the acute blistering of the pharynx or esophagus is treated with systemic corticosteroids. Esophageal strictures are ideally treated by fluoroscopically guided balloon dilatation. However, recurrence of strictures after dilatation is frequent. Gastroesophageal reflux disease usually responds to Histamine 2 – blockers, proton pump inhibitors or pro-motility agents. Growth retardation is common and is thought to occur from insufficient oral intake, increased energy expenditure and malabsorption. Gastrostomy feeding may be necessary to maintain adequate nutrition. Constipation is frequent and alleviation requires adequate fluid and dietary fiber intake, mineral oil, lactulose, osmotic and stimulant laxatives. Pyloric atresia seen in EB with pyloric atresia (EB-PA) is treated by early surgical correction.
Formulation and evaluation of carrot seed oil-based cosmetic emulsions
Published in Journal of Cosmetic and Laser Therapy, 2019
Shalini Singh, Alka Lohani, Arun Kumar Mishra, Anurag Verma
Coconut oil was selected as it acts as an effective moisturizer on all types of skin, including dry skin. The benefits of coconut oil on the skin are comparable to those of mineral oil. Fortunately, unlike mineral oil, there is no chance of having any adverse side effects on the skin upon applying coconut oil. Coconut oil is, therefore, a safe solution for preventing dryness and flaking of skin. It also delays the appearance of wrinkles and sagging of skin, which normally accompany aging. Coconut oil also helps in treating various skin problems including psoriasis, dermatitis, eczema, and other skin infections. For that exact reason, coconut oil forms the base ingredient of various body care products, such as soaps, lotions, and creams, which are used for skin care. Coconut oil also helps in preventing premature aging and degenerative diseases due to its well-known antioxidant properties (17).
Methylnaltrexone bromide for the treatment of opioid-induced constipation
Published in Expert Opinion on Pharmacotherapy, 2018
Shilan Mozaffari, Shekoufeh Nikfar, Mohammad Abdollahi
Management of constipation in different patients is complex due to a variety of underlying causes. Constipation has different pathogenesis. It may be caused by either structural abnormalities of GI tract or other underlying conditions. Therefore, tailored treatments should be considered [5]. Treatment approaches may depend on patient’s age and differ in young and elderly [4]. Most of the patients receiving current treatments remain constipated [8]. Conventional treatments, such as osmotic and stimulating laxatives, are effective in just 50% of patients [5,7,9]. The risk of aspiration with the use of any laxatives such as mineral oils should be considered in pediatric and elderly patients [6]. These agents have shown limited efficacy in the OIC treatment [1]. OIC management is becoming a challenge in patients with chronic pain [7].