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Sleep
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
Lavender: The name L. angustifolia is derived from the Latin word lavare, which means to wash or bathe. The fragrance from lavender oil is believed to induce a calming and sedentary effect to improve sleep and is used as an aromatherapy. Single-blind randomized studies have shown that lavender has a positive impact on energy level, sleep quality, and overall well-being. In a 2018 study of 30 nursing home residents, lavender aromatherapy improved the onset, quality, and duration of sleep in this older adult population.6
Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
The essential oil of lavender, which is obtained from the flowering tops by steam-distillation, is a very common fragrance ingredient. In food manufacturing, it is employed in flavoring beverages, ice-cream, candy, baked goods, and chewing gums. In traditional herbal medicine, it has many applications. In dermatology, lavender oil has been used for wounds, eczema, and psoriasis and even to promote hair growth in alopecia areata. Recent studies have investigated the effectiveness of lavender oils (sometimes in combination with other essential oils) in many health conditions. One of the major applications of lavender oil is in aromatherapy, especially for relief of anxiety, but also as a cure-all for mind, body and spirit, albeit with very little supportive evidence (48), although some would disagree to this statement (64,65).
Herbs with Antidepressant Effects
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
Lavender oil is obtained from steam distillation of the stem, leaves, and flowers of the plant. The primary phytochemical components of the essential oil are linalool, linalyl acetate, ocimene, cineole, terpinen-4-ol, and camphor. Also found are pinene, borneol, myrcene, farnescene, beta-caryophyllene, geraniol, and limonene.2 For hundreds, if not thousands, of years, preparations of Lavandula have been used to treat anxiety, insomnia, arthritis, inflammation, indigestion, and headaches.
Evaluation of toxicological and antimicrobial activity of lavender and immortelle essential oils
Published in Drug and Chemical Toxicology, 2021
Aner Mesic, Irma Mahmutović-Dizdarević, Emina Tahirović, Irma Durmišević, Izet Eminovic, Anesa Jerković-Mujkić, Renata Bešta-Gajević
Immortelle EO (Helichrysum italicum (Roth) G. Don) is very popular in traditional medicine and is used as choleretic, diuretic and expectorant, and for which antimicrobial activity has been demonstrated (Djihane et al. 2017). Furthermore, antiproliferative effect of immortelle EO on the human dermal fibroblasts has been observed (Han et al. 2017). Lavender EO (Lavandula angustifolia Mill.) has been used in treatment of many conditions in humans and animals (Cavanagh and Wilkinson 2005; Uritu et al. 2018). Recent studies have demonstrated genotoxic and antimicrobial effects of lavender oil (Cavanagh and Wilkinson 2002; Di Sotto et al. 2011; Puškarova et al. 2017). Although lavender and immortelle EOs are widely used by humans to treat different conditions, and their mutagenic potential was previously described to a limited extent, at present a little information is available on their cyto/genotoxic and antimicrobial effects. Therefore, the main goal of this study was to comprehensively assess possible cytotoxic and genotoxic potential of lavender and immortelle EOs using plant and human cells, as well as their antimicrobial features through validated antimicrobial assays.
Toxicity assessment of Lavandula officinalis extracts in Brine Shrimp (Artemia salina)
Published in Toxicology Mechanisms and Methods, 2019
Welligton Luciano Braguini, Bruno Bianchin Alves, Natália Valendolf Pires
Lavandula officinalis Chaix (Lamiaceae) has long been used for its antibacterial, antifungal, antidepressant, and analgesic activities (Umezu et al. 2006; Seol et al. 2010; Nikfarjam et al. 2013). Phytochemical studies have revealed that linalool, linalyl acetate, some other monoterpenes and sesquiterpenes, flavonoids such as luteolin, triterpenoids such as ursolic acid, and coumarins such as umbelliferone are the main active constituents in the aerial parts and flowers of L. officinalis, which might contribute to its antihyperlipidemic effects (Rabiei et al. 2014). In addition, lavender oil is most commonly used in aromatherapy and is incorporated in cosmetics and personal care products as an antiseptic and pleasant fragrance (Cavanagh and Wilkinson 2002). Although inhalation of lavender volatile oil has been reported to alter patient mood and improve sleep patterns, the true therapeutic benefits of lavender oil inhalation remain controversial (Cavanagh and Wilkinson 2002; Burnett et al. 2004; Campenni et al. 2004). Kalantar et al. (2017) showed that oral administration of L. officinalis extract significantly lowered methotrexate-induced increase in serum levels of hepatic enzymes, such as alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase. These results are in accordance with several studies reporting that L. officinalis extract reversed the increase in serum hepatic enzyme levels and prevented malathion- and alloxan-induced liver damage (Selmi et al. 2015; Azarmi et al. 2016).
Optimisation of the microencapsulation of lavender oil by spray drying
Published in Journal of Microencapsulation, 2019
Ayah M. Burhan, Sameh M. Abdel-Hamid, Mahmoud E. Soliman, Omaima A. Sammour
The composition of the Lavender essential oil LO was evaluated by chromatographic analysis, which was conducted for both pure lavender oil and the oil extracted from microcapsules produced under optimised conditions. The oil was extracted from the formulation by dissolving 10 grams of each formulation in 150 ml deionised water, then distilling the oil by Clevenger apparatus for 3 h (Bylaitë et al. 2001). The oil extracted was dissolved in hexane and analysed using a Shimadzu GC–MS-QP2010 (Kyoto, Japan) equipped with Rtx-5MS fused bonded column (30 m × 0.25 mm i.d. × 0.25 μm film thickness) (Restek, USA) equipped with a split–splitless injector. The injector temperature was adjusted to 250 °C; the oven temperature was programmed to hold at 45 °C for 2 min, increased from 40 °C to 180 °C at 4 °C min−1, then further increased to 250 °C at 30 °C min−1, where it was held for 2 min. The helium carrier gas flowed at a linear velocity of 40 cm s−1; the split ratio was 1:20; the type of ionisation used was EI 70 eV; and the spectra were acquired by scanning at 45–500 m/z. The compounds were identified by comparison with spectra available in the literature, and the profile of the LO components was expressed as percentage according to the relative peak area (Fernandes et al. 2014).