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Anti-Hyperglycemic Property Of Medicinal Plants
Published in Amit Baran Sharangi, K. V. Peter, Medicinal Plants, 2023
Karanpreet Singh Bhatia, Arpita Roy, Navneeta Bhardavaj
Juniperus communis, commonly known as juniper berry, is a member of Cupressaceae family, and widely grown in North America, Asia, and Europe. It is a small coniferous plant or shrub and has anti-hyperglycemic and anti-hyperlipidemic potential. Sánchez de Medina et al. (1994) reported that juniper decoction at a dosage of 0.25 g/kg, significantly decreased glucose levels in normoglycemic rats and a dosage of 125 mg/kg was efficient for STZ-I hyperglycemic rats. They suggested that the hypoglycemic effect of juniper can be due to either an increase in peripheral glucose consumption or a potentiation of glucose-induced insulin secretion (Sánchez et al., 1994). Methanolic extract of juniper has been evaluated against type 2 diabetes in streptozotocin nicotinamide induced (STZN-I) hyperglycemic rats. A significant reduction in blood glucose level along with different lipid profile parameters was reported (Banerjee et al., 2013).
Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Juniper berry oil is a colorless, sometimes greenish clear mobile liquid, which has a fresh and herbaceous, typical ‘gin’- note odor with fruity-woody note. In juniper berry oils from various origins, over 295 chemicals have been identified. About 45 per cent of these were found in a single reviewed publication only. The ten chemicals that had the highest maximum concentrations in 395 commercial juniper berry essential oil samples are shown in table 6.35.1 (Erich Schmidt, analytical data presented in ref. 8).
Adulteration of Essential Oils
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
ISO standard 8897 shows character and data for this oil. J. communis oil is often mixed up with J. oxycedrus. As marker for that the myrcene content is rising up. Real markers are germacrene D- and δ-cadinene. The sesquiterpene fraction gives more information. Further on, addition of fractions of juniper berry oil from rectification as well as adding juniper branches oil is made. Kartnig et al. (1999) published some chiral data comparing self-distilled and commercial qualities of juniper berry α- and β-pinene, limonene, and terpinen-4-ol oils. Chirality was recognized as useful components for quality control of that oil. Mosandl et al. (1991) report a ratio for (S)-(−)-α-pinene 77%:(R-)-(+)-α-pinene 23%.
Medicinal plants consumption against urinary tract infections: a narrative review of the current evidence
Published in Expert Review of Anti-infective Therapy, 2021
Efthymios Poulios, Georgios K. Vasios, Evmorfia Psara, Constantinos Giaginis
Okragla and coworkers obtained the microtox test, in order to evaluate the antimicrobial activity of herbal infusions, used in UTIs. Herbs used were lingonberry leaf, birch leaf, wild thyme extract, dwarf everlast flower, goldenrod, restharrow, agrimony, rowanberry, black elderberry, and juniper berry. This study evaluated which of the herbal infusions applied for the treatment and reduction of UTIs symptoms exert the highest efficiency, and at which concentration levels (5.85 mg/mL; 0.59 mg/mL; 0.29 mg/mL). The findings of this study supported evidence that the Microtox test may be effectively utilized to evaluate the therapeutic potential of herbal infusions. According to this study, both in preventative medicine, as well as in aiding UTIs treatment, the principal benefit was carried out by herbal infusions of wild thyme and birch leaf (at all concentrations), and also by infusions at higher concentrations (approximately 5.85 mg/mL) of lingonberry leaf, dwarf everlast flower, agrimony, goldenrod, artichoke herb, and juniper berry [49]. In another study, Ukah and coworkers reported a reduced risk of antimicrobial-resistant UTIs, induced by intestinal acquisition of antimicrobial-resistant extraintestinal pathogenic Escherichia coli (ExPEC), related with apples, nectarines, peppers, fresh herbs, and peanuts consumption [50].
Chemopreventive efficacy of juniper berry oil (Juniperus communis L.) on azoxymethane-induced colon carcinogenesis in rat
Published in Nutrition and Cancer, 2021
Turan Yaman, Ahmet Uyar, Ahmet Ufuk Kömüroğlu, Ömer Faruk Keleş, Zabit Yener
The juniper berry (JB), J. communis, is rich in polyphenols, polyphenol esters, and monoterpene hydrocarbons (20, 21). JB oil exhibits a wide range of pharmacological activities due to its high concentrations of α-pinene, P-cymene, and β-pinene (22). JB extract has exhibited significant antioxidant activity against various oxidant systems In Vitro (23). It has been reported that the natural mixture in the J. communis alcoholic extract composition could be used to treat cancer because it has preventive properties specific to the cell cycle (24). Research has also shown that various parts of the JB tree are used in traditional medicine to treat various diseases (25, 26).