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Herbs with Antidepressant Effects
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
There are limited human trials suggesting that Eleutherococcus senticosus can improve symptoms of depression. Subjects described as suffering “neurosis” had significantly improved sleep, well-being, appetite, stamina, cognitive function, and mood after four weeks of treatment with Eleutherococcus senticosus.17 In a randomized study of Eleutherococcus senticosus on quality of life in elderly patients over 65 years of age, improvements in social functioning, mental health, and cognitive function were observed after four weeks of therapy, but these differences did not persist to the eight-week time point.18
Functional Foods
Published in Datta Sourya, Debasis Bagchi, Extreme and Rare Sports, 2019
Kamesh Venkatakrishnan, Chin-Kun Wang
Eleutherococcus senticosus (E. senticosus) is a woody shrub belonging to Araliaceae family, commonly called Siberian ginseng or Acanthopanax senticosus or ciwujia. E. Senticosus’ roots and stem (barks) have been used in traditional Chinese medicine (TCM) for curing various illness as it is a potent adaptogen (anti-stress). The roots of E. senticosus contain several major phytocomponents including sesamin, lignans, coumarin, β-sitosterol and syringaresinol, eleutherosides which contribute to various biological properties (Bai et al., 2011). It exhibits many pharmacological activities including anti-inflammatory, anti-oxidant and anti-microbial (Kimura and Sumiyoshi, 2004; Sumiyoshi and Kimura, 2016). E. senticosus has been suggested to improve cardiorespiratory fitness and endurance performance due to lipolytic and anti-fatigue activity (Goulet and Dionne, 2005; Zhang et al., 2010). Copious numbers of clinical and pre-clinical studies demonstrated that administration of E. senticosus increased VO2 max (exercise tolerance), glycogen contents, β-oxidation of FA (lipolysis) with decreased lactate (upregulating the expression of LDH), BUN and cortisol levels thereby improving athletic performance in different endurance sports (Huang et al., 2011; Kuo et al., 2010; Sumiyoshi and Kimura, 2016).
Herbal medicine for psychiatric disorders: Psychopharmacology and neuroscience-based nomenclature
Published in The World Journal of Biological Psychiatry, 2019
Siu W. Tang, Wayne H. Tang, Brian E. Leonard
Some herbs appear to possess neuroactive properties but have not been clearly shown to have a dominant specific neurotransmitter action. The term ‘adaptogens’ refers to these herbs (Panossian 2013; Levin 2015). Rhodiola rosea, Eleutherococcus senticosus, Schisandra chinensis and Panax ginseng are all within this category. They have been used for centuries for general health enhancement, such as the relief of chronic fatigue (Choi 2016), and also for some specific CNS disorders such as Alzheimer’s disease (Wang et al. 2016a).
Stress management and the role of Rhodiola rosea: a review
Published in International Journal of Psychiatry in Clinical Practice, 2018
Ion-George Anghelescu, David Edwards, Erich Seifritz, Siegfried Kasper
As such, adaptogens should be differentiated from traditional herbal medicinal products of related action, such as tonics and stimulants. The EMA has established HMPC monographs on many herbals including some adaptogens, i.e., preparations deriving from Eleutherococcus senticosus, Panax ginseng and Rhodiola rosea. These monographs cover their therapeutic use and safety as registered drugs.
Rhizome of Anemarrhena asphodeloides as mediators of the eco-friendly synthesis of silver and gold spherical, face-centred cubic nanocrystals and its anti-migratory and cytotoxic potential in normal and cancer cell lines
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Hyun A. Lee, Veronica Castro-Aceituno, Ragavendran Abbai, Seong Soo Moon, Yeon-Ju Kim, Shakina Yesmin Simu, Deok Chun Yang
Nontoxic and available reducing agents for the synthesis of NPs, such as natural plants have opened up new avenues to eco-friendly, simple, rapid and cheap methodologies with biocompatible, scalable and medically applicable nature [36]. To the date, the use of the various medicinal plants to the development of NPs is on focus since not only are used as a reducing agent but also, by creating a capping during the synthesis process some of the pharmacological properties of these plants are transferred. Panax ginseng (P. ginseng) root extract was used for the development of two potential antibacterial and antimicrobial metal NPs [12] and leaves of P. ginseng and Dendropanax morbifera were next used for the synthesis of gold and silver nanoparticles that exhibited similar properties and anticancer properties [37,38]. Similar studies opened a new era of NPs, one that allows the use of plants, such as Pleuropterus multiflorus [21], Cardamom fruits [16], Acanthopanacis cortex [39], Chaenomeles sinensis [40], Prunus serrulata [41] and other plants, that despite their numerous beneficial properties, its usage is limited to specific areas in which are endemic to. The use of the above plants and Anemarrhena asphodeloides, which is used in this study (Figures 6 and 7), have successfully given as a result the synthesize of a variety of metal NPs that exhibited low toxicity to normal cells but at the same time induce toxicity to cancer cells. Furthermore, Aa-AgNPs and Eleutherococcus senticosus mediated Aa-AgNPs induced oxidative stress better than a cAgNPs (Figure 8, [42]). In addition, Aa-AgNPs and AgNPs from Dendropanax morbifera and P. ginseng leaves showed the ability to reduce cell migration in EGF-enhanced A549 lung cancer cells at concentrations from 10 to 25 µg.mL−1 (Figure 9, [11,43]). These results in addition to the previous reports that linked the activation of Caspase-3/MAPK pathways as main regulators of the apoptotic effect of the phyto-mediated synthesized Aa-AgNPs [11,42], suggest that the synthesis method used for the creation of Aa-NPs synthesized in this study just led to the creation of a new promising anticancer agent as it was done in previous studies.