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Potential of Spices As Medicines and Immunity Boosters
Published in Amit Baran Sharangi, K. V. Peter, Medicinal Plants, 2023
Minoo Divakaran, K. Nirmal Babu, K. V. Peter
Dill, botanically belongs to the genus Anethum is derived from Greek word aneeson or aneeton, indicating its strong odor. Dill is commonly used in Ayurvedic medicine to relieve abdominal pain and discomfort, and aiding for digestion. It also cures ulcers, eye diseases and uterine pains. A paste of linseed, castor seeds and dill, in milk for external applications in rheumatic disorders, was prescribed by Charaka. Kashyapa samhitaa, one of the earliest treatises on Indian systems of medicine, endorsed stimulant, revitalizing, and brainpower promoting properties to the herb (A. graveolens). Used in Unani medicine for gripes, digestive problems (Jana and Shekhawat, 2010), it is also effective against reducing fevers.
An Overview of Important Endemic Plants and Their Products in Iran
Published in Raymond Cooper, Jeffrey John Deakin, Natural Products of Silk Road Plants, 2020
Anethum graveolens (Figure 7.19) is an annual plant growing up to 0.8 m by 0.2 m at a medium rate. The flowers are hermaphrodite. The plant is self-fertile. It is noted for attracting wildlife. It is suitable to grow in light (sandy) and medium (loamy) soils and prefers well-drained soil. It is suitable to grow in the soil with acid, neutral, and basic (alkaline) pH. It cannot grow in the shade. It prefers moist soil. The seeds are a common and very effective household remedy for a wide range of digestive problems. The seed is aromatic, carminative, mildly diuretic, galactogogue, stimulant, and stomachic. It is also used in the form of an extracted essential oil. It is used either in an infusion or by eating the whole seed, the essential oil in the seed relieves intestinal spasms and griping, helping to settle colic. Chewing the seed improves bad breath. Dill is also a useful addition to cough, cold, and flu remedies. It can be used with anti-spasmodics such as Viburnum opulus to relieve period pains. Dill is said to contain the alleged “psychotroph”, myristicine (Zargari, 2014; Mozaffarian, 2011; Plant for a Future; Kaur & Arora, 2009).
Myristicin
Published in Dongyou Liu, Handbook of Foodborne Diseases, 2018
C. Martins, J. Rueff, A.S. Rodrigues
Nutmeg oil is also a major constituent of cola flavorings, and myristicin is found in cola drinks, together with the allylbenzene safrole.5 Additionally, certain prepared foods, such as puddings, sweet sauces, and baked goods, contain nutmeg at a level that can reach 0.3% by weight.6 Nutmeg, mace, and dill preparations are also used in traditional medicine (e.g., Chinese, Indonesian, and Ayurveda) to treat rheumatism, cholera, psychosis, stomach cramps, nausea, diarrhea, and anxiety.4,7,8Anethum graveolens L., known as dill, has been used in Ayurvedic medicines since ancient times. The Ayurvedic uses of dill seeds are carminative, stomachic, and diuretic. There are various volatile components of dill seeds and herb, and myristicin is considered to be one of the most important odorants of dill herb.7
The effect of a vaginal suppository formulation of dill (Anethum graveolens) in comparison to clotrimazole vaginal tablet on the treatment of vulvovaginal candidiasis
Published in Journal of Obstetrics and Gynaecology, 2018
Nafiseh Saghafi, Maryam Karjalian, Masumeh Ghazanfarpour, Imaneh Khorsand, Hassan Rakhshandeh, Masumeh Mirteimouri, Masoudeh Babakhanian, Talat Khadivzadeh, Mohammad Javad Najafzadeh, Ahmad Ghorbani, Leila Pourali, Sara Bahman
According to our findings, a 2% dill vaginal suppository was as effective as clotrimazole in relieving the severity of both clinical symptoms like itching, Leucorrhoea and burning, as well as reducing the rate of a positive culture for Candidiasis. Obstetricians can offer dill as a useful alternative to chemical drugs, especially for Iranian women who are often interested in herbal medicine, or for women resistant to the antifungal drug. We further recommend an enlargement of the number of patients included and an evaluation by practical clinical means, especially by slide microscopy.
Anethum Graveolens Essential Oil Nanoemulsions (AGEO-NE) as an Exclusive Apoptotic Inducer in Human Lung Adenocarcinoma (A549) Cells
Published in Nutrition and Cancer, 2022
Haleh Sadat Tavakkol Afshari, Masoud Homayouni Tabrizi, Touran Ardalan, Neda Jalili Anoushirvani, Roya Mahdizadeh
According to the evidence, AGEO is considered as an antioxidant and anticancer compound (15). The essential oil of Anethum graveolens (also known as dill), which is commonly used as a flavoring compound in the food industry, is extracted from the seeds, leaves, and stems of the plant (18). The Anethum graveolens leaves are also widely used in abdominal and colic pain treatment (19). A volatile concentrated hydrophobic liquid of natural sources, essential oils contain bioactive compounds such as flavonoids, phenols, and terpenes, which make up their potent biomedical properties (20). In cancer therapy, the level of specificity applied in cancer diagnosis and treatment strategies are concerning issues and as a result, novel therapeutic approaches and targeted drug delivery systems are being developed for use in anticancer treatments with minimal adverse effects on normal cells (21–23). Due to the non-soluble nature of essential oils and its capabilities in increasing the solubility of non polar therapeutic agents of nanoemulsion systems, they are considered very effective in targeted drug delivery systems and so are used in delivering non-soluble essential oils in the form of natural antioxidants and anticancer drugs. Also, their effective drug delivery enables them to reduce therapeutic side effects, control uptake, and protect against distractive oxidative stresses (24, 25). Moreover, higher stability of nanoemulsions leads to enhanced rapeutic release time. The range of soluble nano-droplets in one of the NE-based drug delivery systems is 20 to 200 nm, which contain encapsulated lipophilic or hydrophilic substances in different environmental conditions (26) and they consume high energy ultrasound waves (108–1010 W/kg) (27). Different types of plant essential oils such as sage (Salvia officinalis), peppermint (Mentha), cajuput, cinnamon, Linum usitatissimum, clove, lavandula (Angustifolia), eucalyptus, and thymus (Vulgaris) act as triggers in NE systems to assess their bio-medicinal activities (28–36), where in their application in drug delivery systems and cancer therapy fields were successfully proven (37). In this regard, several studies targeted human lung cancer to induce apoptotic death by triggering NE-DDs (38, 39). In the current study, anticancer efficacy of the nanoemulsion essential oil of AGEO on A549 cells and its cytotoxic, antioxidant and apoptotic activities were investigated.