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Apiaceae Plants Growing in the East
Published in Mahendra Rai, Shandesh Bhattarai, Chistiane M. Feitosa, Ethnopharmacology of Wild Plants, 2021
Sherweit El-Ahmady, Nehal Ibrahim, Nermeen Farag, Sara Gabr
The most popular traditional use of fennel in the Middle-East is for the relief of gastrointestinal complaints such as irritable colon, flatulence, abdominal pain and constipation. The aqueous extract of F. vulgare showed a remarkable anti-ulcerogenic effect against ethanol-induced gastric lesions in rats (Birdane et al. 2007). An alcoholic extract of the fruits of F. vulgare possesses antispasmodic activity, which inhibits the acetylcholine and histamine-induced guinea pig ileal contractions in vitro. The essential oil, which is obtained from the fruits, inhibited oxytocin and prostaglandin (Forster et al. 1980). The essential oil was shown to regulate the motility of smooth muscles of the intestine, while, at the same time, reducing intestinal gas (Chakŭrski et al. 1981).
Assyria
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
Fennel (Foeniculum vulgare), was used as a carminative and anti-colic agent in conventional medicine in this century (Squire, 1908 p. 540), and is still prescribed in herbal medicine as an antispasmodic and to reduce premenstrual bloating and fluid retention (Rogers, 1995 p. 28).
Use of Essential Oils in Agriculture
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
Catherine Regnault-Roger, Susanne Hemetsberger, Gerhard Buchbauer
Fennel EO caused 100% toxicity to Sitophilus oryzae after exposition for 3 days at concentrations of 3.5 mg/cm3. The EO was even more potent against Callosobruchus chinensis because 100% mortality can be realized at the same concentration after one day (Kim et al., 2003a,b). Compounds of fennel EO were also toxic, as proved in the previous study, to S. oryzae and C. chinensis and also to Lasioderma serricorne. At concentrations of 0.168 mg/cm2, estragole was most toxic to S. oryzae after one day, followed by (+)-fenchone and (E)-anethol. Against C. chinensis, (E)-anethole was most effective, followed by estragol and (+)-fenchone. After one day, (E)-anethole was lethal to L. serricorne, whereas estragole and (+)-fenchone showed lower toxicity (Kim et al., 2001). F. vulgare EO is also potent in controlling Dermanyssus gallinae (Kim et al., 2007). Fennel EO also showed toxic effects to Tyrophagus putrescentiae (Lee et al., 2006), which can possibly be attributed to fenchone, as the isolated compound also showed high mortality rates (Sánchez-Ramos and Castañera , 2001).
Characterization of potentially health-promoting constituents in sea fennel (Crithmum maritimum) cultivated in the Conero Natural Park (Marche region, Central Italy)
Published in Pharmaceutical Biology, 2023
Antonietta Maoloni, Teresa Pirker, Eva-Maria Pferschy-Wenzig, Lucia Aquilanti, Rudolf Bauer
Sea fennel (Crithmum maritimum L.) is an aromatic plant belonging to the Apiaceae family. The plant grows in coastal areas of Mediterranean and Black Sea and Atlantic Europe. It is rich in bioactive substances with nutritional and medicinal value (Alves-Silva et al. 2020). Its fleshy and succulent leaves are used for the preparation of cooked meals, salads, and pickles (Meot-Duros and Magné 2009; Generalić Mekinić et al. 2016). In folk medicine, they are applied as carminative, digestive, vermifuge, diuretic, depurative, anti-inflammatory, tonic, and antiscorbutic drug, as well as in the treatment of wounds and common cold (Atia et al. 2011; Zafeiropoulou et al. 2020). In recent years their ethyl acetate extracts showed activity against hepatocellular carcinoma (HCC) in vitro (Gnocchi et al. 2020), acting on the metabolic pathways (Gnocchi et al. 2021) and on the bioenergetic profile (Gnocchi et al. 2022) of HCC cells, and improving their sensitivity towards sorafenib, a commonly used chemotherapeutic drug (Gnocchi et al. 2023). Sea fennel is characterized by the presence of several bioactive constituents like vitamin C, essential fatty acids, essential oils, and polyphenols. Previous phytochemical studies revealed a high content of phenolic acids, mainly chlorogenic acids (Franke 1982; Cunsolo et al. 1993; Meot-Duros and Magné 2009; Generalić Mekinić et al. 2016, 2018; Pereira et al. 2017; Boutellaa et al. 2019; Najjaa et al. 2020).
The comparison of fennel infusion plus dry cupping versus metformin in management of oligomenorrhoea in patients with polycystic ovary syndrome: a randomised clinical trial
Published in Journal of Obstetrics and Gynaecology, 2019
Roshanak Mokaberinejad, Zahra Rampisheh, Jale Aliasl, Elham Akhtari
In Persian traditional medicine (Iran 2013), menstrual disorders leading to amenorrhoea and oligomenorrhoea have been discussed in detail, with specific therapeutic interventions. A medicinal herb commonly used in this regard is fennel, with the scientific name of Foeniculum Vulgare Mill; which is consumed in a brewed form, such as tea (Aghili Khorasani 2006; Jorjani 2009; Guimarães et al. 2011). Fennel has effects, such as oestrogenic effects; including oestrogen phase formation, weight gain in the mammary gland, endometrial weight gain, cervical and anti-oxidant effects (Escop 2003). In Persian traditional medicine, this herb relieves pain in the uterus and increases lactation, is used to treat infertility (Salehi et al. 2017), and polycystic ovary syndrome (Akhtari et al. 2017). Fennel is commonly used in Persian medicine to treat menstrual disorders.
Effect of Foeniculum vulgare (fennel) on symptoms of depression and anxiety in postmenopausal women: a double-blind randomised controlled trial
Published in Journal of Obstetrics and Gynaecology, 2018
Masumeh Ghazanfarpour, Fatemeh Mohammadzadeh, Paymaneh shokrollahi, Talat Khadivzadeh, Mona Najaf Najafi, Hamidreza Hajirezaee, Maliheh Afiat
Flow of subjects is shown in Figure 1. By the end of the study data from 49 patients, 25 patients in the intervention group and 24 cases in the placebo group were analysed (Figure 1). Two patients in the fennel group and two in the placebo group displayed side effects. The patients treated with fennel complained of frequent urination and spotting (these cases, however, was not related to malignancy or endometrial proliferation) and patient placebo group complained of stomach ache. The mean age of the patients in the intervention and control groups was respectively 57.04 ± 4.67 and 54.79 ± 4.22 years. Demographic characteristic of two groups are shown in Table 1.