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Sarcoidosis
Published in Charles Theisler, Adjuvant Medical Care, 2023
Various NSAIDs: Nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Nuprin, Motrin IB), naproxen sodium (Aleve, Naprosyn), aspirin, or others, may help reduce acute joint inflammation and relieve pain and fever.7
Community Retail Pharmacies
Published in Rupa S. Valdez, Richard J. Holden, The Patient Factor, 2021
Michelle A. Chui, Ashley Morris, David Mott
Many older adults incorrectly reported that OTCs are safe because of their availability without prescription or that they were safe with other medications as long as the label did not specifically warn against it. Most reported reading the labels, but noted that even when they read the label and saw “what’s in it,” that the active ingredients did not have inherent meaning to them. Older adults had significant difficulty making comparisons between medications due to the overwhelming number of similarly marketed choices in the OTC aisles. Even in cases in which participants made direct comparisons between two medications, labels were still misinterpreted, (e.g. a participant stated she could not take extra acetaminophen because of her prescriptions, but then selected a combination product containing acetaminophen). In another case, a participant noted a previous negative reaction to ibuprofen and then stated she could only take Advil (brand name for ibuprofen). Although older adults reported that their pharmacist was a valuable resource for prescription information, they were often reluctant to ask questions about OTC medications, in part due to their perceptions that all OTC medications are safe.
Chronic Pain Management and Arthritis
Published in Deborah Fish Ragin, Health Psychology, 2017
Other NSAIDs that are also effective in reducing inflammation include ibuprofen, a generic drug more commonly known by the brand names Motrin, Advil, or Excedrin. Ibuprofen, regardless of the manufacturer, can also cause stomach distress and thus poses similar risks to those of aspirin regimens. Somewhat stronger NSAIDs include naproxen—brand name Aleve—and ketoprofen—brand name Acton (Khan, 2006). Naproxen and ketoprofen are believed to be more effective because they block the body’s natural production of COX-1 and COX-2, enzymes that help protect the stomach lining (COX-1) and that produce inflammation (COX-2).
Provider-directed analgesia for dental pain
Published in Expert Review of Clinical Pharmacology, 2023
Several new products have emerged with potential application to managing acute dental pain. For example, an FDA-approved OTC product consisting of acetaminophen (325 mg) and ibuprofen (125 mg) (Advil Dual Action®). Naltrexone is an opioid antagonist used in managing alcohol and opioid use disorders, but in low doses, often referred to as low-dose naltrexone (LDN), it can used off-label for managing chronic pain conditions (e.g. TMJ) since it possesses anti-inflammatory, analgesic, and even immunomodulator effects [192]. Its potential role in treating acute dental pain following surgical extractions is unclear at this time. Repurposing of established non-opioid agents, such as antidepressants and muscle relaxants, might have promise as adjuvant therapies but further clinical research is needed to establish their efficacy in acute dental pain models [184]. Discovery of novel druggable targets in the pain pathway (e.g. non-mu opioid receptors, cannabinoid receptors, metalloproteinases, vanilloid receptor) is a popular field of research and will likely spur development of new drug entities that eventually reach the consumer market [193].
The lived experience of sport-related concussion: A collaborative inquiry in elite sport
Published in Journal of Applied Sport Psychology, 2022
Cassandra M. Seguin, Diane M. Culver
In the quarterfinal game, Evan went in for a tackle and the back of Evan’s head was hit hard by his teammate’s forehead, leaving them both bloody. Off the pitch, the team’s medical doctor and athletic therapist attended to their wounds. Evan felt a bit dizzy and had a headache but shrugged it off. His doctor gave him some Advil and asked him how he was feeling. Evan thought to himself: ‘this is THE Olympics! I can’t let the guys down’. Evan turned to his doctor, swallowing the Advil and said: ‘I’m fine doc, just a light knock on the head, no big deal’ and returned to play. He had never been diagnosed with a concussion despite suspecting a couple over the years, but he was fairly certain this was one. He played through the game, but he knew something wasn’t right; his headache grew sharper and he was getting dizzier by the minute.
A method for the tribological assessment of oral pharmaceutical liquids
Published in Drug Development and Industrial Pharmacy, 2022
Hyun Joo Lee, R. Gary Hollenbeck, Jill A. Morgan, Amy Kruger Howard, Akhtar Siddiqui, Vilayat A. Sayeed, Arzu Selen, Stephen W. Hoag
A selection of oral liquid products with differing physical properties was obtained: sugarless syrup vehicle (Versa Free™, Humco, Texarkana, TX); sugarless suspension vehicle (Versa Plus™, Humco, Texarkana, TX); bismuth subsalicylate suspension 17.5 mg/mL (Pink Bismuth, Rite Aid Corporation, Camp Hill, PA); magnesium hydroxide suspension 400 mg/5 mL (Phillips’ Milk of Magnesia, Bayer Corporation, Leverkusen, Germany); calcium carbonate 80 mg/mL and magnesium hydroxide 27 mg/mL antacid suspension (Mylanta, Johnson & Johnson-Merck, New Brunswick, NJ); ibuprofen suspension 20 mg/mL (CareOne Children’s Ibuprofen Oral Suspension, American Sales Co., Lancaster, NY); concentrated ibuprofen suspension 40 mg/mL (Infants Advil Drops, Whitehall-Robins Healthcare, Richmond, VA); acetaminophen suspension 32 mg/mL (Children’s Non-Aspirin Oral Suspension Liquid, Rite Aid Corporation, Camp Hill, PA); dextromethorphan polistirex extended-release suspension equivalent to 6 mg/mL dextromethorphan hydrobromide (Delsym, Reckitt Benckiser Inc., Rochester, NY). All products were used as received; Table 1 gives a description of these products’ characteristics and their abbreviations.