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Published in Ashfaq A Marghoob, Ralph Braun, Natalia Jaimes, Atlas of Dermoscopy, 2023
Amélie Boespflug, Félix Pham, Ralph P. Braun, Luc Thomas
Lichen planus can affect the nails. Nails are thinned and show longitudinal ridging and fissuring with distal splitting. Dermoscopy shows multiple deep longitudinal fissures reaching the distal part of the nail as well as the partial absence of the nail plate. Dermoscopy can be useful to follow up and evaluate treatment response (16, 29, 33).
Oral Diseases
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Marcia Ramos-e-Silva, José Wilson Accioly Filho, Sueli Carneiro, Nurimar Conceição Fernandes
Management: Pure and asymptomatic oral lichen planus, in general, does not need treatment. For the more severe and/or symptomatic cases, triamcinolone in Orabase®, applied four or more times a day may be helpful. Rinsing the mouth with doxycycline or tetracycline dissolved in water may reduce the symptoms. Oral steroids are sometimes necessary. Clofazimine and colchicine have also been used. Cryosurgery is an option for treating the hypertrophic form.
Lichen planus
Published in Robert Baran, Dimitris Rigopoulos, Chander Grover, Eckart Haneke, Nail Therapies, 2021
Lichen planus typically affects the skin, nails, vulva, penis, and mucous membranes including the mouth (Table 5.1). LP affects one or more nails in 1%–15% of the cases. Fingernails are found to be more commonly affected than toenails; however, both can be affected.
Lichen Planus in Ocular Surface: Major Presentations and Treatments
Published in Ocular Immunology and Inflammation, 2019
Masoomeh Mohebbi, Masoud Mirghorbani, Ali Banafshe Afshan, Mohsen Towfighi
Lichen planus (LP) is an autoimmune disease mainly affecting the skin and the mucous membranes. Its exact prevalence is unknown; however, in different epidemiologic studies, reports were between 0.07% and 0.84%.1 The disease is equally distributed in genders except for oral mucosal LP in which women predominance of 1.4:1 or 2:1 has been reported.1 The typical age of patients is between 30 and 60 years old, and only 1–3% of patients are children.2,3 LP has diverse cutaneous, mucosal, and subungual manifestations alone or in combination with each other. The estimated frequency of mucosal involvement is about 30–70%.4 The most common site of involvement in mucosal LP is the oral mucosa followed by genitalia, esophageal, and nasopharyngeal involvement.1 Ear canals and ocular surfaces are the other sites of involvement.5,6 The typical course of the disease is an acute inflammation of the skin or mucosal tissues presenting with sores and erosion. After a self-limiting inflammation, the disease presents with a chronic benign course with fibrous bands and scarring.1 With a literature search, one can find that there are not many reports on ocular surface involvement in LP as it is very uncommon. Much of these reports are related to the conjunctival involvement with the subsequent cicatrizing conjunctivitis, while the others are about lacrimal and even corneal involvement in LP. To have a comprehensive conception of the LP manifestations in ocular surface disorders, we reviewed and summarized what had been reported before.
Treatment of cutaneous lichen planus (Part 1): A review of topical therapies and phototherapy
Published in Cogent Medicine, 2019
Yasmeen Thandar, Rivesh Maharajh, Firoza Haffejee, Anisa Mosam
Lichen planus is a skin condition which has been named as it resembles the “lichens” in the plant world. It is an itchy, chronic problem which can go on for years as it can be difficult to control and the itching can be distressing for those affected. In some patients, it can cause significant scarring. Although various treatment options have been used in the treatment of lichen planus, it is still challenging to choose the most effective one. In this investigation, all topical treatments used were evaluated so that both doctors and patients could be better informed about their choices. It was found that topical steroids, the first line of treatment for lichen planus, have not been investigated enough to prove that they work. Light therapy in the form of ultraviolet light has been shown to be effective and should be used before embarking on oral treatments for lichen planus.
Lichen sclerosus of the oral mucosa: clinical and histopathological findings. Review of the literature and a case report
Published in Acta Odontologica Scandinavica, 2018
Anna-Maija Matela, Jaana Hagström, Hellevi Ruokonen
When oral lichen planus appears as a white reticular form or as white plaques, it may appear similar as oral LS. Clinically, lichen planus usually exhibits a bilateral and symmetrical manifestation in the oral cavity. The histopathological picture changes depending on the form of the lichen planus lesion and the site of the biopsy. Atrophic, ulcerated and reticular forms have different histopathological features. In lichen planus, hyperkeratosis is detected in sections of white reticular areas (Wickhams striae) between areas of atrophy. Liquefaction degeneration of basal cells and a band-like, dense lymphocyte infiltration (primarily T cells and macrophages) are seen next to the basal cells. Mature oral LS differs from lichen planus regarding hyalinization, loss of elastic fibres and lymphocyte infiltration situated deeper in lamina propria [35,39].