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Benign Oral and Dental Disease
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Konrad S. Staines, Alexander Crighton
Denture-related stomatitis (chronic atrophic candidiasis) is the most common form of mild, chronic, oral candidiasis. It occurs only beneath a denture or other appliance and, despite its name, is not often sore. Dentures worn throughout the night, or with a dry mouth, favour development of this infection and occasionally there is a mixed infection with staphylococcal species. An accumulation of microbial plaque on and in the fitting surface of the denture and the underlying mucosa predispose to making the clinical appearance persist. This condition is managed exclusively by proper denture hygiene including removing the denture at night, cleaning the denture properly and treating it regularly with an appropriate antiseptic. There is no need for a topical antifungal except in the immunocompromised. If untreated the patient may develop papillary hyperplasia of the tissues beneath the denture which can complicate the provision of a new denture in the future.
Microbiological evaluation of an experimental denture cleanser containing essential oil of Lippia sidoides
Published in Biofouling, 2021
Joel Oliveira Barreto, Francisca Bruna Stefany Aires do Nascimento, Said Gonçalves da Cruz Fonseca, Letícia Serpa Sampaio, Cecília Rocha da Silva, João Batista de Andrade Neto, Hélio Vitoriano Nobre Júnior, Rômulo Rocha Regis
For the bacteria tested, the greatest MIC/MBC values were observed for P. aeruginosa (625/2,500 µg ml−1). Previous studies demonstrated sensitivity of bacteria such as S. aureus to LSEO and moderate antimicrobial activity against P. aeruginosa (Lemos et al. 1990; Bertini et al. 2005), confirming the present results, which suggest that LSEO products may have limited action against Gram‐negative bacteria. C. albicans is the most prevalent species in denture-related stomatitis and it is often associated with bacteria (Chow and Clyne 2012; Harriott and Noverr 2011; Morales et al. 2010; Shirtliff et al. 2009). S. aureus is a Gram-positive pathogen capable of expressing multiple virulence factors and resistance genes (Peters et al. 2010). P. aeruginosa is an opportunistic Gram-negative prokaryote that has a high rate of infection in immunocompromised patients and is capable of producing a variety of virulence factors, including lipopolysaccharides and proteases (Morales et al. 2010; Kart et al. 2014). Such microorganisms can act synergistically, forming multispecies biofilms, increasing their virulence potential in several oral infections (Kart et al. 2014).