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Paper 3
Published in Aalia Khan, Ramsey Jabbour, Almas Rehman, nMRCGP Applied Knowledge Test Study Guide, 2021
Aalia Khan, Ramsey Jabbour, Almas Rehman
Concerning blepharitis, which one of the following is true? Topical chloramphenicol is the treatment of choice.Eyelid hygiene is first-line treatment.It is an acute painful condition.Contact lenses may not be worn.Visual acuity is impaired.
Ophthalmic Emergencies
Published in Anthony FT Brown, Michael D Cadogan, Emergency Medicine, 2020
Anthony FT Brown, Michael D Cadogan
Blepharitis is an infection of the eyelid margin, causing red, itchy, crusted lids, which may become chronic with seborrhoeic dermatitis, rosacea or allergy. Styes and chalazions are commonly associated.
Cellulitis and Swelling around One or Both Eyelids
Published in Amy-lee Shirodkar, Gwyn Samuel Williams, Bushra Thajudeen, Practical Emergency Ophthalmology Handbook, 2019
Check the thyroid status of the patient as unilateral or bilateral eyelid swelling and erythema is often a subtle feature of thyroid eye disease. A flare up of blepharitis may also be responsible for an acute unilateral or bilateral swelling of the eyelids, but is often accompanied with soreness, itchy eyes, photophobia and possibly discharge.
Investigation of the Demodex Lid Infestation with in Vivo Confocal Microscopy versus Light Microscopy in Patients with Seborrheic Blepharitis
Published in Ocular Immunology and Inflammation, 2022
Ceyhun Arici, Burak Mergen, Hrisi Bahar Tokman, Ayse Yildiz Tas, Edip Tokuc, Yesim Ozturk Bakar, Afsun Sahin
Blepharitis is one of the most common ocular pathologies encountered in clinical practice. It is a chronic inflammatory disorder of the eyelid margins that can be observed in any age group.1 While survey studies estimate its prevalence at 37–47%, a cross-sectional study reported that 8.6% of patients had symptomatic and 21.9% of patients had asymptomatic meibomian gland dysfunction.2,3 Blepharitis can be classified according to its location as anterior, posterior, or mixed. Staphylococcal and seborrheic blepharitis comprise the anterior blepharitis group, whereas meibomian gland dysfunction comprises the posterior blepharitis as the primary cause. While anterior blepharitis affects eyelid skin, follicles, and the base of the eyelashes, posterior blepharitis affects meibomian glands and their orifices.1
The Effect of Therapeutic Meibomian Glands Expression on Evaporative Dry Eye: A Prospective Randomized Controlled Trial
Published in Current Eye Research, 2021
Igor Kaiserman, Gilad Rabina, Michael Mimouni, Naava. B. Sadi Optom, Nitsan Duvdevan, Shmuel Levartovsky, David Ben David
At baseline, mean blepharitis questionnaire scores were 24.0 ± 11.5 and 22.5 ± 7 in the study and control groups, respectively (p = .13). One week after the first treatment, the blepharitis questionnaire scores showed a significant improvement in the study group (−9.95 ± 12.52, p < .001) compared to the control group (−1.77 ± 9.142, p = .27) (p = .03). After 1 month of treatment, the mean improvement in blepharitis questionnaire scores was greater in the study group, compared to baseline (−11.5 ± 10.9 p = .001) while there was minimal to no improvement in the control group (−1.1 ± 9.4, p = .61), p = .02. The improvement was also seen at 2 months in the study group (−16.5 ± 8.0, p < .0001) and a much smaller improvement in the control group (−8.8 ± 11.75, p = .02).
Advances in understanding of Netherton syndrome and therapeutic implications
Published in Expert Opinion on Orphan Drugs, 2020
Evgeniya Petrova, Alain Hovnanian
NS patients develop recurrent skin infections predominantly with Staphylococcus aureus. Secondary infections with S.aureus can trigger flares (personal observation) [9]. Blepharitis due to Staphylococcus aureus are also frequently observed. Fungal and viral infections (except for HPV in papillomatous lesions) are unusual. Other skin complications include lichenification in flexor creases with thickening of the skin as in atopic dermatitis. NS patients can also develop papillomatous skin lesions in particular in the groin, perineal and genito-anal regions, which can be HPV positive and can evolve into a giant condyloma of Buschke-Löwenstein tumor Figure 2 [10–12]. Squamous cell carcinomas of the skin have been reported in a few cases of adult NS patients [13].