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Sexual Dysfunction
Published in Peter Sagar, Andrew G. Hill, Charles H. Knowles, Stefan Post, Willem A. Bemelman, Patricia L. Roberts, Susan Galandiuk, John R.T. Monson, Michael R.B. Keighley, Norman S. Williams, Keighley & Williams’ Surgery of the Anus, Rectum and Colon, 2019
The use of robotic surgery in laparoscopic rectal resections has been suggested as onemethod of reducing the risk of nerve injury, as it has been shown to offer this benefit inrobotically assisted laparoscopic radical prostatectomy. It has been suggested that robotictechniques improve direct visualisation and hence identification of the fine neurovascularstructures by virtue of the stereoscopic vision and improved tissue handling by the‘wrist’ articulation of the intracorporeal instrumentation. Evidence for a reduction insymptoms of pelvic nerve injury is, at present, very limited.16,17
Artificial Olfactory Systems Can Detect Unique Odorant Signature Of Cancerous Volatile Compounds
Published in Raquel Cumeras, Xavier Correig, Volatile organic compound analysis in biomedical diagnosis applications, 2018
Roine et al. (2014) evaluated the ability of an e-nose system to discriminate prostate cancer from benign prostatic hyperplasia using urine headspace (Roine et al., 2014). The study was performed in 50 patients with prostate cancer and 15 patients with benign prostatic hyperplasia scheduled for robotic assisted laparoscopic radical prostatectomy or transurethral resection of the prostate; from the latter group, 9 patients provided urine samples also at 3 months after surgery, which served as control. Urine headspace was analyzed with the handheld ChemPro® 100-eNose (Environics Oy, Finland), consisting of an Ion Mobility Spectrometry cell and six semiconductor gas sensors. Data analysis was conducted using linear discriminant analysis and logistic regression. Using leave-one-out cross-validation, the e-nose reached a sensitivity of 78% and a specificity of 67%, which are comparable with the results of the prostate specific antigen testing, the common approach to detect prostate cancer.
Integrative hyperthermia treatments for different types of cancer
Published in Clifford L. K. Pang, Kaiman Lee, Hyperthermia in Oncology, 2015
Clifford L. K. Pang, Kaiman Lee
Radical prostatectomy (referred to as radical resection) is the most effective method for the treatment of localized prostate cancer, with three main operations, namely, traditional perineal, retropubic, and laparoscopic radical prostatectomy, developed in recent years. Timing of surgery: patients with transrectal biopsy should wait for 6–8 weeks, and patients with transurethral resection of prostate should wait for 12 weeks before surgery, so as to avoid the inflammatory response causing rectal and surrounding tissue damage. Also, nervesparing surgery is easier. In addition, percutaneous cryoablation has accurate positioning, minimal trauma during surgery, and good postoperative recovery. It has also been widely used clinically.
The risk of inguinal hernia repair after radical prostatectomy – a population-based cohort study
Published in Scandinavian Journal of Urology, 2022
Mikko Ahtinen, Jaana Vironen, Teemu J. Murtola
Spermatic cord isolation and processus vaginalis transection are standard techniques in minimally invasive hernia repair. Standard hernia repair includes placing mesh to reinforce the weakened inguinal canal region. To our knowledge, using mesh as a prophylactic method during prostatectomy has not been studied. After prostatectomy, the mesh may be exposed to contaminated urine, thus to possible infection. However, multiple studies have evaluated simultaneous inguinal hernia repair and robot-assisted laparoscopic radical prostatectomy. In these publications, mesh placement has not increased morbidity or complications of prostatectomy [23,24]. In line with that, prophylactic mesh placement has been under active study focusing on preventing parastomal hernia, and results suggest this to be a safe approach despite high contamination risk [25,26].
Post-Radical Prostatectomy Erectile Dysfunction Assessed Using the IIEF-5 Questionnaire – A Systematic Literature Review
Published in International Journal of Sexual Health, 2022
Tomasz Jurys, Bartlomiej Burzynski, Anna Potyka, Andrzej Paradysz
In each of the studies included in the systematic review of the literature, the assessment of erectile dysfunction was made using the IIEF-5 questionnaire. All studies was published in English language. Despite the fact that the questionnaire has existed since 1999, the oldest article that qualified for the final analysis was from 2005. The qualifying studies come from 13 different countries, 13 in Europe, 3 in South America, 3 in Asia and 2 in North America. Eight studies were randomized clinical trials, and the remaining 13 were observational, comparative, or case series. The total number of respondents from all finally selected studies was 17,641. The most common time point for assessing erectile dysfunction was 12 months after surgery, although dysfunction was also assessed with equal frequency at 3 and 6 months after surgery. The mean age of the majority of the study population was over 60 years. The available information on the clinical tumor grade shows that the cT1, cT2 and cT3 grades were the most common in the prostate cancer population. In turn, the most common pathological stage of the cancers was pT2, pT3 and pT4. The most common surgical techniques used in the studies were radical retropubic prostatectomy and robot-assisted radical prostatectomy, while the most seldom used was laparoscopic radical prostatectomy. The characteristics and a summary of the results of the studies included in the review are presented in Table 1.
Quality of life assessment using EORTC QLQ questionnaires in the prostate cancer population treated with radical prostatectomy: a systematic review
Published in Scandinavian Journal of Urology, 2021
The studies included in this review all used the EORTC QLQ questionnaires as a concept. Of these, six were from Europe and were conducted in four different countries, and the remaining two were from Asia. One of the studies had a clinical trial design, while the other seven had a cohort design, with a total of 1936 patients. The most frequent follow-up time for assessment of quality of life after radical prostatectomy was one year post-surgery or earlier [14–20], but study evaluated the cohort only once after surgery (i.e. at 6 months) [21]. The mean age of patients in the the majority of the studies was over the age of 60. The clinical stage of tumor in the patients, where such information was included, was similar: cT1-cT2 [15,16,20], cT1-cT3 [14,18], However, one of the studies evaluated a group of patients at the cT2-cT3 stage of tumor. The most commonly used surgical technique was radical retropubic prostatectomy (RRP), while laparoscopic radical prostatectomy (LRP) was the rarest technique used in this review. Characteristics and summaries of the studies included in the qualitative synthesis are shown in Table 2.