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Fibrocystic Breasts/Cystic Mastitis/Mammary Dysplasia
Published in Charles Theisler, Adjuvant Medical Care, 2023
Vitamin E: Doses of vitamin E (400–600 mg/day) have been reported to afford symptomatic improvement in fibrocystic breast disease.4 Studies have also shown a beneficial effect of vitamin E on breast pain in premenstrual women who experience breast pain that fluctuates during the menstrual cycle.
Cancer of the Breast
Published in Jennifer L. Kelsey, Nancy G. Hildreth, Breast and Gynecologic Cancer Epidemiology, 2019
Jennifer L. Kelsey, Nancy G. Hildreth
At the present time, the biologic basis for the association between fibrocystic breast disease and breast cancer is unknown. One possibility is that cystic disease is a pre-malignant condition. Findings from autopsy studies167,168 of women who did not seek care for breast disease indicate that several parts of the breast may contain undiagnosed fibrocystic disease. Also, cancer is just as likely to develop in the breast opposite to the one in which the cystic disease had been diagnosed.147–149 These observations suggest that many possibly premalignant cells are dispersed throughout the breasts of some women with fibrocystic disease; the diagnosed cystic disease may be only the most obvious part of a widely dispersed pathologic process. On the other hand, an abnormal hormonal milieu may exist in some women with fibrocystic disease that makes all breast epithelial cells “premalignant” or susceptible to a carcinogenic factor.
The Menstrual Cycle and Other Parameters Affecting Breast Disease and Detection
Published in Diana L. Taylor, Nancy F. Woods, Menstruation, Health, and Illness, 2019
Although no testing procedure correlated with total methylxanthines (coffee, cocoa, tea, chocolate, and cola), significant chocolate consumption (p = .042) was found in women with abnormal physical examinations. Methylxanthines have been linked to fibrocystic breast disease (Minton, Foecking, Webster, & Matthews, 1979a). It had been hoped to show a correlation between intake and diagnosis, as caffeine withdrawal has proven to effectively reduce or eliminate the symptoms associated with fibrocystic breast disease (Gonzales, 1980; Minton, Foecking, Webster, & Matthews, 1979b). In the final analysis, women with cancer had consumed significantly more coffee (43 versus 8 cups per week, p = .003) and total methylxanthine (p = .020).
What is the position of testosterone in the care of women?
Published in Climacteric, 2019
Since that time, women have been treated with testosterone for diverse reasons. The most prominent clinical indication has been low sexual desire. Past proposed indications have also included fibrocystic breast disease3 and breast cancer4,5. However, more recently women have reportedly been treated with testosterone for non-traditional indications including ‘hot flushes, sweating, sleep disturbance, heart discomfort, depressive mood, irritability, anxiety, premenstrual syndrome, fatigue, memory loss, menstrual or migraine headaches, vaginal dryness, sexual problems, urinary symptoms including incontinence, musculoskeletal pain and bone loss’6. Whether any of these aforementioned clinical complaints justify treatment of women with testosterone has been contentious.
High prevalence of benign mammary tumors in a rat model of polycystic ovary syndrome during postmenopausal period
Published in Gynecological Endocrinology, 2019
Mahsa Noroozzadeh, Samira Behboudi-Gandevani, Nariman Mosaffa, Maryam Tohidi, Fahimeh Ramezani Tehrani
The incidence of fibrocystic breast disease is 7% in the general population [4]. Previous studies have reported a significant association between PCOS and benign breast diseases (BBD), e.g. fibrocystic breast disease and increased prevalence of BBD in these patients [5,6], in whom this may be due to hormonal imbalances and anovulation, that are involved in the etiology of BBD [4,6].