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Genodermatoses
Published in Dimitris Rigopoulos, Alexander C. Katoulis, Hyperpigmentation, 2017
Cutis tricolor is another congenital pigmentary disorder, in which multiple hyper- or hypopigmented macules, patches, or streaks are present on normal skin, in a Blaschko line distribution, commonly on the trunk and arms. There is an association with neuropsychiatric abnormalities and ipsilateral breast hyperplasia. Cutis tricolor represents a mosaicism with three genetically different cell lines.62–64
Sexuality and Rehabilitation Following Acquired Brain Injury
Published in Barbara A. Wilson, Jill Winegardner, Caroline M. van Heugten, Tamara Ownsworth, Neuropsychological Rehabilitation, 2017
Jennie L. Ponsford, Marina Downing, Rene Stolwyk
There has been much less research on sexuality in stroke populations. Although the mechanisms of brain injury and average age of the stroke population differ from those in TBI, the potential impact of stroke on sexuality is still significant. Regardless of age, intimate relationships represent an important contributor to quality of life for most adults. As Duits et al. (2009) point out, whereas physical impairment will influence sexual positions and movement during sex, depression and medication may reduce sexual desire. According to Stein et al. (2013), factors associated with sexual dysfunction following a stroke may include fatigue, neurological or neuromuscular weakness and spasticity, and hemianaesthesia. Neuroendocrine dysfunction may cause erectile dysfunction in males and decreased vaginal lubrication and orgasmic ability in females. Additionally, atherosclerosis may cause reduction in blood flow that affects end organs, including genitalia. Other physiological changes may include decreased libido, anorgasmia, priapism, retarded or premature ejaculation, retrograde ejaculation, breast hyperplasia, gynecomastia and others. The prevalence of major depression after stroke is reported to range from 16 per cent to 40 per cent within the first year (El Husseini et al., 2012) and can affect sexual function. Additionally, hypersexuality and emotional lability have been related to sexual dysfunction post-stroke (Calabrò, Gervasi and Bramanti, 2011). Other reasons for low sexual drive include psychological factors such as fear of rejection from a partner, changes in body image and alterations in relationship dynamics. Thus many of the potential causes of sexual changes following stroke parallel those associated with TBI.
Iatrogenic pneumothorax after breast reduction surgery caused by local anesthesia infiltration – a case report
Published in Case Reports in Plastic Surgery and Hand Surgery, 2022
Marko T. Ristola, Ilkka Koskivuo, Salvatore Giordano
On 12 September 2019 she underwent breast reduction mammoplasty for breast hyperplasia and subsequent neck and shoulder region pain and stiffness. The mammoplasty was performed under general anesthesia with propofol and an I-Gel® laryngeal mask with sevoflurane. Before the initial incision, one of the operating surgeons, a senior consultant plastic surgeon and chief of the department of plastic surgery, infiltrated a local anesthetic consisting of 20 ml of ropivacaine 7.5 mg/ml, 20 ml of lidocaine 5 mg/ml with adrenalin 10 microg/ml in each breast, for a total of 40 ml of local anesthetic solution per breast. The needle used was a 21 G needle, 0.8 mm thick and 80 mm long. The infiltration technique used was a combination of intradermal and intramammary injection deep into the breast tissue, in a somewhat perpendicular direction to the chest wall. After infiltration of the local anesthetic solution, the procedure was performed in a standard fashion using a Wise pattern technique with a superomedial pedicle. During the operation, no inconsistencies or abnormalities were noted in either the surgical side or the anesthesia side, and the operation was carried out routinely.
Effects of different doses of estrogen on ER expression and ovarian function in patients with unexplained recurrent abortion
Published in Gynecological Endocrinology, 2022
Yamin Qiu, Jie Lin, Qing Xu, Linhua Zeng, Chao Liu
In clinical practice, estrogen and pregnancy stimulus are commonly used for sequential treatment. However, due to the lack of uniform treatment guidelines, the dosage of hormone therapy is different, the course of treatment is different, and the ratio of progesterone is different, so the curative effect varies greatly. When the number of endometrial receptors is reduced or the function is abnormal, the endometrial proliferation ability is decreased, and the responsiveness to estrogen stimulation under physiological conditions is reduced. It is speculated that it may be related to the reduction and saturation of estrogen receptors. Therefore, in the hormone therapy of URSA, high-dose estrogen is mostly used, ignoring the side effects of high-dose estrogen. Roy [18] and other studies have shown that for some patients, the treatment of high-dose estrogen has little effect. Some researcher even believe that high-dose estrogen will cause endometrial fibrosis and affect the expression of receptors [19]. High-dose hormone therapy also has risks of breast hyperplasia, gastrointestinal reactions, weight gain, liver and kidney damage, thrombosis, and cardiovascular and cerebrovascular diseases.
Glycine Max (L.) Merr isoflavone gel improves vaginal vascularization in postmenopausal women
Published in Climacteric, 2020
S. M. R. R. Lima, J. V. Honorato, M. A. L. G. Silva
The exclusion criteria were use of hormone therapy currently or in the previous 6 months; a diagnosis of malignant neoplasm of the breast, uterus, or endometrium; present or past history of thromboembolism; abnormal genital bleeding of unknown cause; porphyria; history of atypical breast hyperplasia or mammography disclosing significant abnormality; previous endometriosis; endometrial echo detected on transvaginal ultrasound >5 mm; genital prolapse grades II, III, or IV; and abnormalities in Pap smear screening (low or high-grade squamous intraepithelial lesion, atypical squamous or glandular cells of undetermined significance, and cervical neoplasia).