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Acute Neuropathic Pain
Published in Pamela E. Macintyre, Stephan A. Schug, Acute Pain Management, 2021
Pamela E. Macintyre, Stephan A. Schug
The diagnosis of neuropathic pain can usually be made on the basis of a complete history and basic physical examination (see Chapter 3). Patients will typically describe their pain as “strange” and different from “normal” wound pain.
Mechanisms of Pain
Published in Benjamin Apichai, Chinese Medicine for Lower Body Pain, 2021
Neuropathic pain is caused by injury to the nerves that send the wrong pain signals to the brain. This type of pain is typically described as tingling, numb, tight, prickling, itching or like the sensation of needles, electric shock, burning, or shooting that is often intense and chronic. The pain can be intermittent or continuous. Examples include stroke, diabetes, postherpetic neuroglia, vitamin B deficiency, phantom limb pain, and carpal tunnel syndrome.
Exergaming for Health and Fitness Application
Published in Christopher M. Hayre, Dave J. Muller, Marcia J. Scherer, Everyday Technologies in Healthcare, 2019
Maziah Mat Rosly, Hadi Mat Rosly, Mark Halaki
The perception of pain during exercise was commonly reported by individuals experiencing disabilities related to traumatic injuries (Mat Rosly et al., 2017c, 2018). However, pain resulting from any traumatic injury to the neural nervous systems is known to be non-nociceptive, exacerbated by its chronic neuropathic nature (Varoto and Cliquet, 2015). Neuropathic pain is difficult to manage clinically, with pharmacological interventions only providing temporary symptomatic relief. Exergaming environments have documented evidence of pain distraction whilst exercising (Mat Rosly et al., 2017c; Pekyavas and Ergun, 2017). This may be attributed to the pathway mechanics of pain stimulation, which could be overlapped by the visual and auditory feedback during exergaming (Jerdan et al., 2018). However, there is not enough evidence to support reduction of chronic pain through non-pharmacological interventions in these individuals, and further work is needed to support this claim (Boldt et al., 2014). An important key strength for deploying exergaming as a feasible exercise modality is the perceived enjoyment supporting its use, as reported by several studies among those with neurological disabilities (Malone et al., 2016; Widman et al., 2006; Mat Rosly et al., 2017c). Higher enjoyment scores were reported to improve motivation and maintain adherence rates to exercise (Pekyavas and Ergun, 2017; Widman et al., 2006), which may help in alleviating ongoing perception of pain.
Continuing professional development needs in pain management for Canadian health care professionals: A cross sectional survey
Published in Canadian Journal of Pain, 2023
Craig M. Dale, Iacopo Cioffi, Christine B. Novak, Franklin Gorospe, Laura Murphy, Deepika Chugh, Judy Watt-Watson, Bonnie Stevens
The top identified condition for continuing knowledge development among those caring for adult and older adult populations was neuropathic pain, which has a high impact on quality of life and increasing prevalence in North America.25 Compared with other pain issues, neuropathic pain is likely to be rated as more severe.26 Symptoms of neuropathic pain such as burning, numbness, and allodynia can be difficult for patients to describe. This may be particularly true of institutionalized older adults, who often experience self-report incapacities.27 Taken together, these issues may contribute to problems diagnosing neuropathic pain outside of specialty settings. Moreover, the modest to moderate benefit of conventional analgesics for neuropathic pain may factor into treatment uncertainties among HCPs and lack of pain relief among patients.28 HCP trainees in Canada have limited exposure to patients with persistent chronic pain conditions. This training gap may leave them unclear about appropriate care in practice.29
Nanoencapsulation and characterisation of Hypericum perforatum for the treatment of neuropathic pain
Published in Journal of Microencapsulation, 2023
Radha Goel, Nitin Kumar, Neelam Singh, Rosaline Mishra
Neuropathic pain is one of the many factors that contribute to the global burden of disease (Sukmawan et al.2021). It is caused by damage to somatosensory nervous system and affects around 7% of the population (Szok et al.2019). Several traditional drugs, including opioids, anticonvulsants, NSAIDs, and antidepressants, are available for neuropathic treatment, but they do not provide acceptable pain relief in many individuals. Most of these people want safe treatment, as they are concerned about serious side effects such as dizziness, nausea, vomiting, stomach ache, heartburn, etc. with the traditional therapy for neuropathic pain. Hence, in this prospect, herbal therapy may thus give a high-level alternative with superior therapeutic results and fewer adverse effects in the future (Kumar et al.2021).
Utilizing network pharmacological analysis to investigate the key targets and mechanisms of kaempferol against oxaliplatin-induced neurotoxicity
Published in Toxicology Mechanisms and Methods, 2023
Hongxing Wang, Jing Quan, Youming Deng, Jie Chen, Ke Zhang, Zhan Qu
Neuropathic pain is a chronic debilitating condition caused by a dysfunction or injury of the somatosensory system which induces the occurrence of pain response to touch stimuli (allodynia), abnormal and unpleasant feelings (dysesthesia), and painful stimuli (hyperalgesia) (Finnerup et al. 2016). The previous report indicated that the prevalence of neuropathic pain may be around 10%; it seriously compromises the life quality of sufferers (van Hecke et al. 2014). Although previous studies revealed that neuroimmune regulation, cancer chemotherapy, spinal cord injury, and diabetic neuropathy were involved in the etiopathogenesis of neuropathic pain (Costigan et al. 2009; Cohen and Mao 2014; Malcangio 2019; Yang et al. 2019). The pathogenesis of neuropathic pain is complex and has poor understanding.