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The respiratory system
Published in C. Simon Herrington, Muir's Textbook of Pathology, 2020
Fungal infections, e.g. aspergillosis, may form fungal balls, cause sinusitis, or rarely be invasive. Other fungi may affect this region, but they are more commonly seen in Asia and Africa. Rhinosporidiosis, caused by Rhinosporidium seeberi, is transmitted by cattle and horses, and causes granulomatous nasal polyps.
Fungal Infections
Published in John C Watkinson, Raymond W Clarke, Louise Jayne Clark, Adam J Donne, R James A England, Hisham M Mehanna, Gerald William McGarry, Sean Carrie, Basic Sciences Endocrine Surgery Rhinology, 2018
Emily Young, Yujay Ramakrishnan, Laura Jackson, Shahzada K. Ahmed
Rhinosporidiosis is an infectious disease caused by an aquatic protozoan previously considered to be a fungus. The aetiologic agent of rhinosporidiosis, Rhinosporidium seeberi, is closely related to several protoctistiae fish pathogens. The infection affects nasal mucous membranes and ocular conjunctivae of humans and animals, producing slowly growing masses that degenerate into polyps. As this is no longer considered to be a fungal pathogen it will be considered no further in this chapter.
Neoplasms of the Nasal Cavity of Cattle and Sheep
Published in Gerd Reznik, Sherman F. Stinson, Nasal Tumors in Animals and Man, 2017
This fungal infection is characterized grossly by presence of soft, pinkish growths approximately 2 to 3 cm in diameter in the nasal cavity. The growths are polypoid and may resemble nasal neoplasms in cattle. It is, however, a chronic rhinitis caused by Rhinosporidium seeberi. Histologically the growth is composed of fibrous or fibromyxoid stroma with intact epithelial covering. There is a mixed population of epitheloid cells and few lymphocytes associated with spherical fungal bodies of various sizes in the tissue stroma.
Nasopharyngeal rhinosporidiosis with intracranial extension masquerading as juvenile angiofibroma: an unusual entity
Published in British Journal of Neurosurgery, 2022
Gautam Dutta, Ghanshyam D. Singhal, Daljit Singh, Hukum Singh, Arvind Kumar Srivastava, Anita Jagetia
Initially considered to be an unclassified fungus,1Rhinosporidium seeberi is the causative organism of a chronic, granulomatous disease process called Rhinosporidiosis. This disease is characterized by a reddish, polypoidal, friable hyperplastic mass, mostly affecting the nasal cavity and mainly involving the anterior part of nasal septum, vestibule and nasopharynx. Extranasal involvement is rare2 and includes sites like lips, palate, uvula, conjunctiva, larynx, trachea, penis, vagina and even long bones.3 Intracranial extension of nasopharyngeal rhinosporidiosis has not been previously described. We report on a case of nasopharyngeal rhinosporidiosis that presented with extensive involvement of the paranasal sinuses with intracranial extension which radiologically mimicked juvenile nasopharyngeal angiofibroma (JNA). To our knowledge, this is the first reported case of rhinosporidiosis having such atypical presentation.