China
Africa
Explore chapters and articles related to this topic
Infectious Disease
Published in John S. Axford, Chris A. O'Callaghan, Medicine for Finals and Beyond, 2023
Susanna J. Dunachie, Hanif Esmail, Ruth Corrigan, Maria Dudareva
Secondary: If untreated, the individual may progress to the secondary stage approximately 2–4 months after the initial infection. This is characterized by a non-pruritic maculopapular (Figure 3.21) or pustular rash which often involves palms and soles (Figure 3.22). Wart-like lesions, known as condyloma latum, may appear around mucous membranes. The rash may be accompanied by fever and lymphadenopathy and other constitutional symptoms. Untreated, these symptoms will resolve but a latent infection will persist.
Penile Cancer
Published in Manit Arya, Taimur T. Shah, Jas S. Kalsi, Herman S. Fernando, Iqbal S. Shergill, Asif Muneer, Hashim U. Ahmed, MCQs for the FRCS(Urol) and Postgraduate Urology Examinations, 2020
Hussain M. Alnajjar, Asif Muneer
Condyloma acuminatum is a predominantly a sexually transmitted infection caused by human papillomavirus (HPV) and spread through oral, anal and genital sexual contact and is therefore a benign condition. All of the other genital dermatoses are associated with penile SCC. Lichen sclerosus and Bowenoid papulosis are sporadically associated with penile SCC, whereas, Paget’s disease and Buschke-Löwenstein are precancerous lesions and up to 30% transform into invasive SCC.
Retinoids in Other Skin Diseases
Published in Ayse Serap Karadag, Berna Aksoy, Lawrence Charles Parish, Retinoids in Dermatology, 2019
Uwe Wollina, Piotr Brzezinski, André Koch
A 15-year-old boy with recalcitrant giant condylomas was treated with a combination of 25 mg acitretin/day and Mycobacterium indicus pranii vaccination immunotherapy. Complete clearance was obtained after 6 months of acitretin with no recurrence within the next 2 years of follow-up (74). A 16-year-old girl with HPV-6-positive giant condyloma acuminatum was cured by a combination of intramuscular interferon-gamma 1 MIU/day and oral acitretin 30 mg/day after 3 months of treatment (75).
Reported rationales for HPV vaccination vs. Non-vaccination among undergraduate and medical students in South Carolina
Published in Journal of American College Health, 2021
J. Barrera, S. Greene, E. Petyak, S. Kenneson, E. McGill, H. Howell, D. Billing, S. Taylor, A. Ewing, J. Cull
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States. Infection with HPV can cause cervical neoplasia and condyloma acuminatum (genital warts), as well as cancers of the oropharynx, vagina, penis, and anus. The quadrivalent vaccine, which targets HPV types 6, 11, 16, and 18, became available in 2006 and was first approved for females ages 9–26. In 2009, the vaccine was additionally approved for males ages 9–21 and those 22–26 with associated risk factors (men who have sex with men or the immunocompromised). National vaccination objectives for this group are aimed at 80%.1 In the United States, approximately half of new infections with HPV occur before the age of 24, making college and graduate students a critical population for monitoring the prevalence of HPV. However, most recent data demonstrates the prevalence of HPV infection has decreased in this cohort.2
CO2 laser treatment for pearly penile papules – personal experience
Published in Journal of Cosmetic and Laser Therapy, 2019
Anna Deda, Aleksandra Lipka-Trawińska, Sławomir Wilczyński, Barbara Błońska-Fajfrowska
The lesions, prior to their removal, were diagnosed, including differential diagnosis for condyloma acuminata and molluscum contagiosum (11). PPP do not contain human papilloma virus and there is no relationship between the occurrence of condyloma and PPP (21). Molluscum contagiosum can be distinguished clinically from PPP based on umbilicated papules that are larger in size (3). In the dermoscopic image, PPP resemble grape-shaped structures where each lesion contains characteristic blood vessels in the shape of dots or commas (19,22). However, it should be noted that this vascular pattern is not characteristic and can also be observed in the case of condyloma (22,23). Nevertheless, PPP have a more homogeneous structure in the dermoscopic image due to the absence of exfoliation (23).
Proteomic and bioinformatic analysis of condyloma acuminata: mild hyperthermia treatment reveals compromised HPV infectivity of keratinocytes via regulation of metabolism, differentiation and anti-viral responses
Published in International Journal of Hyperthermia, 2019
Yu-Zhe Sun, Jia-Feng Li, Zhen-Dong Wei, Hang-Hang Jiang, Yu-Xiao Hong, Song Zheng, Rui-Qun Qi, Xing-Hua Gao
Condyloma acuminatum (CA) is a common, sexually-transmitted disease observed worldwide that develops from human papillomavirus (HPV) infection. Among all HPV subtypes, CA is primarily the result of either a HPV 6/11 (low-risk types) or HPV 16/18 (high-risk types) infection [1]. CA patients are typically treated with physical therapies such as CO2 laser ablation and cryotherapy, however, recurrence is oftentimes observed due to failures in eliminating invisible HPV-infected loci [2]. Although 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) is effective in treating latent HPV infection and reducing recurrence of CA [2], the relatively high medical expenses and pain associated with this therapy limits its application, especially in patients with massive lesions. Therefore, there exists a clear need for the development of more effective and economic therapeutic methods.