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The Use of Capillaroscopy and Aggregometry Methods to Diagnose the Alterations of Microcirculation and Microrheology in Diabetes
Published in Andrey V. Dunaev, Valery V. Tuchin, Biomedical Photonics for Diabetes Research, 2023
Andrei E. Lugovtsov, Yury I. Gurfinkel, Petr B. Ermolinskiy, Anastasia A. Fabrichnova, Alexander V. Priezzhev
It was shown that the aggregation of RBCs increases with an increased content of glucose, triglycerides, alipoprotein B, total cholesterol, C-reactive protein in the blood plasma, ESR in the blood. However, the dependence of aggregation on glycated hemoglobin levels, which is often used as a criterion for metabolic control of diabetes, has not been identified in all studies [40,41]. This may be likely because glycated hemoglobin reflects an average metabolic control of 3 months by the time of its measurement, while glucose levels are a more direct indicator of diabetes compensation.
Herbs with Antidepressant Effects
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
Panax ginseng has been reported to improve insulin resistance, reduce inflammation, and enhance resiliency to stress, which together would be expected to counter the ongoing syndrome of MDD. In one report, daily Panax ginseng elevated mood, improved psychophysical performance, and reduced fasting blood glucose and body weight in non-insulin-dependent diabetic patients. These changes were reflected in reductions in glycated hemoglobin levels.7 A more recent randomized, double-blind, placebo-controlled study also showed improvement in glycemic control and enhancement of insulin sensitivity.8
The approach to revision procedures
Published in Gregory D. Schroeder, Ali A. Baaj, Alexander R. Vaccaro, Revision Spine Surgery, 2019
Joseph A. Weiner, Wellington K. Hsu
Glycated hemoglobin (HbA1c) can be used to diagnose and monitor diabetes and poor glycemic control. Both the American Diabetes Association and American Association of Clinical Endocrinologists advocate the use of HbA1c > 6.5% to diagnose DM.57 Koutsoumbelis et al. reported that a clinical diagnosis of diabetes prior to surgery significantly increased the risk for postoperative infection after instrumented lumbar fusion.24 Recent work has further demonstrated that both controlled and uncontrolled diabetic patients undergoing degenerative lumbar spine surgery have an increased risk of postoperative infection.58
Relationship between Physical Activity and Health Outcomes in Persons with Psychotic Disorders after Participation in a 2-Year Individualized Lifestyle Intervention
Published in Issues in Mental Health Nursing, 2023
Marjut Blomqvist, Andreas Ivarsson, Ing-Marie Carlsson, Anna Sandgren, Henrika Jormfeldt
The need for implementation of lifestyle interventions has been established due to increased risk of physical diseases and excess mortality in this population (Correll et al., 2017; Vancampfort et al., 2016; Westman et al., 2018), and makes it important to investigate the health effect of individualized lifestyle intervention in the context of psychiatric outpatient services. There is also a need to establish best practice assessment and monitoring procedures within exercise interventions in severe mental illness (McMahen et al., 2022). Glycated hemoglobin (HbA1c) can be used as a diagnostic test for assessing glycemic control in persons with diabetes, and as a screening test for persons at high risk of diabetes. The blood count reflects average plasma glucose over the previous 8 to 12 wk (World Health Organization, 2011).
Proteinuria in early referral to spectral domain optical coherence tomography for macular edema detection in type 2 diabetes individuals: results from the Brazilian diabetes study
Published in Current Medical Research and Opinion, 2022
Joaquim Barreto, Fernando Chaves, Vicente H. R. Fernandes, Daniel Campos de Jesus, Mauricio Abujamra Nascimento, Rodrigo P. C. Lira, Wilson Nadruz, Carlos Arieta, Andrei C. Sposito
After 12 h fasting, peripheral blood samples were collected and centrifuged at 3500 rpm for 10 min, and plasma samples were stored at −20 °C until analysis. Glycated hemoglobin was measured by high-performance liquid chromatography (HPLC) (D-100, Bio-Rad, California, USA). ELISA methods were employed in the following measurements: serum creatinine (K625, Biovision, Massachusetts, USA), urea (K376, Biovision, Massachusetts, USA), total cholesterol, high-density lipoprotein (HDL-C), and triglycerides (ab287836, Abcam, Cambridge, UK). Low-density lipoprotein (LDL-C) was calculated by the Friedewald equation23. Spot urine samples were analyzed on the same day using ELISA assays for albumin-to-creatinine ratio (ACR) (ab241018, Abcam, Cambridge, UK) and protein-to-creatinine ratio (PCR) (ab272539, Abcam, Cambridge, UK) estimation. A PCR of ≥0.20 mg/g or an ACR ≥ 30 mg/g was abnormal. ACR results were thereupon classified as: normal (<30 mg/g), microalbuminuria (30–300 mg/g), or macroalbuminuria (>300 mg/g). The glomerular filtration rate was estimated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation and an eGFR less than 60 m/min/m2 was abnormal24,25.
Evaluation of right side foetal myocardial performance index in pregestational and gestational diabetes mellitus
Published in Journal of Obstetrics and Gynaecology, 2022
Gökalp Şenol, Berna Aslan Çetin, Didem Esin, Nura Fitnat Tobaş Selçuki, Ahmet Tayyar, Uğur Turhan, Zafer Bütün, Mehmet Aytaç Yüksel
Gestational diabetes mellitus (GDM) is the most commonly seen metabolic disorder in pregnancy, affecting 10–25% of all pregnancies (Jiwani et al. 2012). Foetal hyperinsulinism is the reason for foetal complications in gestational and pregestational diabetes (Salvesen et al. 1993). Elevated levels of glycated haemoglobin are associated with an increased risk of malformation (Macklon et al. 1998). Hyperglycaemia affects most likely the myocardial tissue. Although its effect on foetal heart is not fully understood, it is thought to be due to many factors. The literature shows that pregestational diabetes mellitus decreases ventricular compliance and causes foetal cardiomyopathy and foetal diastolic dysfunction (Zielinsky et al. 2004). The foetus is at risk of myocardial hypertrophy and diastolic dysfunction even in pregnancies with satisfactory glycemic control (Rizzo et al. 1995).