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Anemia
Published in Charles Theisler, Adjuvant Medical Care, 2023
Anemias are a group of diseases characterized by a significant reduction in the amount of healthy red blood cells or hemoglobin, resulting in a corresponding decrease in the blood’s oxygen carrying capacity to the cells and tissues. Anemia is the most common blood disorder in the world, affecting more than three million individuals and is often a sign of underlying pathology. If the anemia onset is gradual, a person may not be symptomatic until the hemoglobin level is less than 8 gm/dL.1 Symptoms often include fatigue, pale skin, rapid heart beat or palpitations, poor appetite, shortness of breath, and dizziness. There are many different types and causes of anemia.
Translating the Medical Record
Published in Walter F. Stanaszek, Mary J. Stanaszek, Robert J. Holt, Steven Strauss, Understanding Medical Terms, 2020
Walter F. Stanaszek, Mary J. Stanaszek, Robert J. Holt, Steven Strauss
Blood studies assess disorders of cell production (hematopoiesis), synthesis, and function. Examination of the blood and bone marrow are the primary means of determining blood disorders. Venipuncture is used to procure larger samples of blood for testing. Bone marrow specimens are obtained through needle biopsy or aspiration. A hemogram includes platelet count, white blood cell count (WBC), red blood cell count (RBC), hematocrit (Hct), and indices. A complete blood count (CBC) includes a hemogram plus differential count.
Plants Species with Anticancer Activity
Published in Spyridon E. Kintzios, Maria G. Barberaki, Evangelia A. Flampouri, Plants That Fight Cancer, 2019
Evangelia Flampouri, Spyridon Kintzios, Maria Barberaki
The successful clinical introduction was substantially delayed, largely due to problems with insolubility and instability, particularly of the ring E lactone. Late diarrhea (generally occurring more than 24 hours after administration of Camptosar®) can be life threatening since it may be prolonged and may lead to dehydration, electrolyte imbalance, or sepsis. Late diarrhea should be treated promptly with loperamide. Patients with diarrhea should be carefully monitored and given fluid and electrolyte rement if they become dehydrated or antibiotic therapy if they develop ileus, fever, or severe neutropenia. The most common side effects with Hycamtin® (topotecan hydrochloride) are infections. Blood disorders are also common, where reduced levels of certain blood cells may cause anemia, reduced resistance to infections, and increased bruising or bleeding.
Cost-effectiveness of baloxavir marboxil compared with laninamivir for the treatment of influenza in patients at high risk for complications in Japan
Published in Current Medical Research and Opinion, 2021
Mariia Dronova, Hidetoshi Ikeoka, Naoya Itsumura, Nobuo Hirotsu, Amir Ansaripour, Samuel Aballéa, Yoshie Onishi, Mark Hill, Ataru Igarashi
The following list of HRC was considered in line with the Centers for Disease Control and Prevention’s definition and phase III clinical trial of baloxavir3,8:Asthma or chronic lung disease.Endocrine disorders.Compromised immune system.Neurological and neurodevelopmental disorders.Heart disease (excluding hypertension).Blood disorders.Metabolic disorders.Morbid obesity.Women within 2 weeks postpartum – for patients aged <65 years only.Residents of long-term care facilities – for patients aged ≥65 years only.
Trends, predictors, and outcomes of major bleeding after transcatheter aortic valve implantation, from national inpatient sample (2011–2018)
Published in Expert Review of Cardiovascular Therapy, 2021
Salman Zahid, Waqas Ullah, Muhammad Usman Khan, Sakina Abbas, Mian Tanveer Ud Din, Muhammad Faisal Uddin, Arslan Inayat, Aamer Ubaid, Fnu Salman, Samarthkumar Thakkar, Amr Salama, Muhammad Zia Khan
The higher bleeding complications with baseline hematological problems related to platelets and coagulation factors were identified in our study. These findings are reinforced by a well described association of major bleeding events with blood disorders in previous literature [9]. In addition to this, patients with ESRD have a propensity to bleed due to the inherent platelet dysfunction and thus are associated with high mortality [10,[11]. Similarly, Liver disease patients have increased tendency to bleed due to associated coagulopathy [12]. These findings were reinforced in a previous meta-analysis consisting of 1652 patients where chronic liver disease patients had higher incidence of mortality, bleeding complications and need for blood transfusions [13]. This association is further exacerbated by anti-platelet and anticoagulant drug use [14,[15].
Screening tools for hereditary hemolytic anemia: new concepts and strategies
Published in Expert Review of Hematology, 2021
Elisa Fermo, Cristina Vercellati, Paola Bianchi
In the recent years, the interest in rare diseases is increasing, particularly by the European Commission (within the 7th framework programme and Horizon 2020), by promoting initiatives for research and the creation of European Reference Netwoks. The EuroBloodNet network focused on hematological disorders has been officially approved by the European Commission in 2016, and gathers highly skilled and multidisciplinary healthcare teams in 15 Member States, with the main mission to facilitate concentration of resources for the design, validation and implementation of high-quality and cost-effective services, including diagnosis (www.eurobloodnet.org). Moreover, a consensus document involving more than 300 experts highlighting major achievements in diagnosis and treatment of blood disorders (including RBC disorders) has been published by members of the European Hematology Association [77]. As a result it is auspicable that the implementation of networking activities will allow in the next future to further rise the interest in this group of disorders and to facilitate their diagnosis.