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Cancer
Published in Gia Merlo, Kathy Berra, Lifestyle Nursing, 2023
The association of metabolic syndrome and cancer is noteworthy in considering the role of adiposity in cancer risk. Metabolic syndrome is defined by the presence of three or more of the following: High blood sugar, high blood pressure, high triglycerides, low HDL cholesterol, and elevated waist circumference. Metabolic syndrome is associated with 20% to more than 60% increased risk of several cancers (Micucci et al., 2016). Metabolic syndrome signals likelihood of dysfunctional adipose tissue, inflammation, insulin resistance, and dysregulated hormones and signaling proteins (Neeland et al., 2019) that could enhance cancer development.
Metabolic Syndrome
Published in Jahangir Moini, Matthew Adams, Anthony LoGalbo, Complications of Diabetes Mellitus, 2022
Jahangir Moini, Matthew Adams, Anthony LoGalbo
Metabolic syndrome is actually a group of risk factors that increases risks for diabetes mellitus, heart disease, stroke, and other health problems. There must be at least three of the following metabolic risk factors in order for metabolic syndrome to be diagnosed: A larger than normal waist circumference, high triglyceride level, low HDL cholesterol level, hypertension, and high fasting blood sugar. The risk of having metabolic syndrome is closely linked to obesity and lack of physical activity, as well as insulin resistance. Metabolic syndrome is becoming more common because of increased obesity rates. Conditions that play a role in the development of metabolic syndrome include fatty liver disease, polycystic ovarian syndrome, and respiratory conditions such as obstructive sleep apnea. Metabolic syndrome is treated with a combination of lifestyle improvements and medications.
Physical inactivity and health
Published in Sally Robinson, Priorities for Health Promotion and Public Health, 2021
Physical activity seems to protect against developing metabolic syndrome (Ekelund et al., 2007; Healy et al., 2008; Sisson, 2010). Metabolic syndrome is when someone has a cluster of risk factors including obesity, high waist circumference, type 2 diabetes, poor glucose regulation, insulin resistance, high blood pressure and high blood cholesterol. They are vulnerable to developing type 2 diabetes and cardiovascular disease. Physical activity strengthens the heart, which reduces high blood pressure, helps to control the ‘bad’ LDL blood cholesterol and increases the ‘good’ HDL blood cholesterol.
Emergency Medical Services Clinicians Have a High Prevalence of Metabolic Syndrome
Published in Prehospital Emergency Care, 2023
Michael W. Supples, Nancy K. Glober, Thomas A. Lardaro, Simon A. Mahler, Jason P. Stopyra
Several modifiable behaviors associated with metabolic syndrome may be targets for intervention, including smoking, BMI, diet, and physical activity (47). Using survey methodology, Cash et al.(4) estimated approximately half of nationally registered EMS clinicians had suboptimal behaviors for cardiovascular health. Effective strategies to reduce the prevalence of metabolic syndrome in EMS clinicians may target poor dietary habits and lack of engagement with regular physical activity. Lifestyle interventions including dietary modifications and increased physical activity effectively reduce the effects of metabolic syndrome in the general population (48). Unfortunately, EMS clinicians face numerous barriers to health habits, including lack of time, energy, resources, and social support (44). A majority of EMS clinicians work overtime or at multiple jobs (49), suggesting meaningful interventions will need to be time- and cost-efficient, and likely embedded in the existing clinician culture and infrastructure. Improving the socioeconomic factors experienced by EMS clinicians, such as improved wages and safer work schedules, could be a means to improving EMS clinician health. Effective interventions to improve diet and physical activity engagement for EMS clinicians have not yet been described in the literature.
Hyperglycaemia and the risk of post-surgical adhesion
Published in Archives of Physiology and Biochemistry, 2022
Gordon A. Ferns, Seyed Mahdi Hassanian, Mohammad-Hassan Arjmand
Metabolic syndrome is a complex of disorders such as hypertension, hyperglycaemia and diabetes, obesity and dyslipidemias (Alberti et al.2009). Previously, we have shown the relationship between visceral adiposity with inflammation and risk of post-surgical adhesion (Arjmand 2020). Adipose tissue is a possible connector in inflammatory state in patients with metabolic syndrome. Adipokines produced in adipose tissues, induces chronic inflammation (Karamanos et al.2016). Diabetes and high blood glucose is one of other common disorder in metabolic syndrome which can increase inflammation, oxidative stress, and the expression of profibrotic molecules as described in previous sections. Linking of metabolic syndrome with basic biological mechanism of adhesion formation has been demonstrated in some studies. For example, there is a positive correlation between metabolic syndromes with hypercoagulability (Ramos-Levi et al.2013), or the relation between type 2 diabetes and obesity in inducing inflammatory conditions in metabolic syndrome. Attempt to lose weight for reducing adipose tissue and balance blood sugar is recommended prior elective surgeries.
Prevalence of benign prostatic hyperplasia among the adult general population of five Middle Eastern Countries: Results of the SNAPSHOT programme
Published in Arab Journal of Urology, 2022
Amr Noweir, Ashraf Abusamra, Abdelqader Al Zarooni, Murat Binbay, Adam Doble, Luqman Tariq, Fayaz Aziz, Abdelkader El Hasnaoui
Consistent with the published literature [15], the present study found that chronic conditions, associated with BPH included cardiovascular disease, diabetes, and renal diseases. Given the high incidence of obesity in the screening population, and the age of the subjects, the impact of cardiovascular disease is not unexpected, as obesity and older age both increase the risk of cardiovascular disease. Given the frequent occurrence of these conditions in ageing men, a large proportion of patients can be expected have such an association. In addition, there is a large body of evidence supporting an association between metabolic syndrome, which comprises at least three of the five following features: abdominal obesity, high blood pressure, impaired blood glucose or diabetes, elevated serum triglycerides and reduced high-density lipoprotein, and LUTS [16]. There are numerous reports of an association between diabetes mellitus and BPH, specifically hyperglycaemia and insulin resistance [17]. Chronic kidney disease has also been shown to be associated with BPH [18].