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Lifestyle and Diet
Published in Chuong Pham-Huy, Bruno Pham Huy, Food and Lifestyle in Health and Disease, 2022
Chuong Pham-Huy, Bruno Pham Huy
In summary, all diets described previously have the same common base: a preference for many plant foods, seafoods, and their byproducts; an avoidance of processed meats and saturated fats; and limited consumption of red meat. The major characteristics of the Okinawan diet are low calorie intakes, preference of colorful sweet potato, tofu, turmeric, and seaweeds, and regular physical activities such as walking and doing housework. Perhaps due to these foods, their physical activities, or to their genes, Okinawans are the oldest people in the world, with the highest level of centenarians.
Healing the Heart with Whole Foods and Food Bioactives
Published in Stephen T. Sinatra, Mark C. Houston, Nutritional and Integrative Strategies in Cardiovascular Medicine, 2015
Analysis of the traditional Okinawan diet has revealed that Okinawans were in a negative energy balance of approximately 11% until the 1960s (before progressive westernization of their diet).54 Notably, the traditional Okinawan diet shares many general features of the Mediterranean and DASH diets, however, it also characteristically includes a high consumption of green leafy vegetables, sweet potato, soy foods, seaweeds, herbs and spices and low consumption of dairy products and daily green tea.55
Brief, effective experience to increase first-year medical students’ nutrition awareness
Published in Medical Education Online, 2021
Mary Thoesen Coleman, Paula Rhode Brantley, Pamela Markiewicz Wiseman, M. Robin English, Lauri O. Byerley
Medical students, like most individuals, have gaps in their nutrition knowledge and dietary habits, which, if addressed, could help with handling any potential adverse effects of a high-stress environment. Diets such as the Okinawan diet, Mediterranean diet, and DASH (Dietary Approaches to Stop Hypertension) diet share features such as being high in vegetables and fruit but reduced in meat, refined grains, saturated fat, sugar, and salt. This balance is thought to increase antioxidant intake and lower glycemic load, thus contributing to a healthier lifespan [15,16]. Certain foods, particularly those incorporating complex carbohydrates, proteins, vitamin C, B vitamins, magnesium, and selenium, are thought to play an important role in stress management [17]. In a 2016 analysis of the dietary practices of pharmacy and medical students at ten schools in California, only 50% had a saturated fat intake of <10% of total kcal, 13% met their fiber intake goals, and 10% consumed greater than eight servings/day of fruit and vegetables [18]. Fifty-nine percent cited lack of time as the biggest barrier to a healthful diet.
Present and emerging pharmacotherapies for non-alcoholic steatohepatitis in adults
Published in Expert Opinion on Pharmacotherapy, 2019
Yuji Ogawa, Masato Yoneda, Takashi Kobayashi, Yasushi Honda, Takaomi Kessoku, Kento Imajo, Satoru Saito, Atsushi Nakajima
Lifestyle interventions and dietary changes to achieve weight reduction and improve insulin sensitivity are recommended for patients with NAFLD [1,28]. Recently, usefulness of the Okinawan diet, which is calorie-poor, but nutritionally dense, particularly with regard to phytonutrients, has been shown to be useful for patients with NASH [29,30]. However, the effectiveness of these interventions is difficult to sustain over the long term, because many patients are unable to either initiate or maintain the required dietary and lifestyle changes [28,31]. There is a critical need to develop pharmacologic therapies for the treatment of NASH. Until date, there are no therapies for treating NASH that are approved by the Federal Drug Administration (FDA) or European Medicines Agency (EMA). Phase 2 and phase 3 trials of many new drugs under development are ongoing. This review focuses on the clinical development of several emerging drugs for the treatment of NASH and the impact of these drugs on the current treatment standards.