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Orthotopic Total Small Bowel Transplantation in the Rat
Published in Waldemar L. Olszewski, CRC Handbook of Microsurgery, 2019
Although not strictly necessary, it is advantageous to perform the delicate preparation of the donor organ and the anastomoses of the blood vessels under a dissecting microscope. The donor small bowel is prepared by dissecting the mesenteric artery from the surrounding tissue up to the aorta pedicle, ligating tributary branches with 6/0 silk. The superior mesenteric vein is carefully separated from pancreatic tissue, double-tying and dividing all venous branches. Proximal jejunum and terminal ileum are divided, after which the lumen of the isolated part of the small bowel can be irrigated with a saline/neomycin solution (0.5%). After heparinizing the animal systemically (1 mℓ of a solution containing 50 U heparin in saline), the connecting blood vessels are divided in such a way that a patch of aortic material is left to the mesenteric artery. The portal vein is cut as high as the porta hepatis, after which the small bowel is removed to a jar containing cold saline. The organ blood system is flushed with cold saline, which may contain some heparin.
Anatomy
Published in Peter Sagar, Andrew G. Hill, Charles H. Knowles, Stefan Post, Willem A. Bemelman, Patricia L. Roberts, Susan Galandiuk, John R.T. Monson, Michael R.B. Keighley, Norman S. Williams, Keighley & Williams’ Surgery of the Anus, Rectum and Colon, 2019
Reza Mirnezami, Alex H. Mirnezami
The ileocaecal valve is a rudimentary structure consisting of two horizontal folds of mucous membrane that project around the orifice of the terminal ileum. The caecum receives its arterial blood supply from the ileocolic artery via anterior and posterior caecal branches (Figure 1.2). Veins drain into corresponding branches of the superior mesenteric vein. Lymphatic drainage is to local paracolic nodes and ultimately to the superior mesenteric lymph node basin. Autonomic nerve supply is provided by the superior mesenteric plexus via sympathetic and parasympathetic nerve fibres.
The Small Intestine
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
Possible sources for embolisation of the SMA include the left atrium in atrial fibrillation, the left ventricle after mural myocardial infarction, vegetations on mitral and aortic valves associated with endocarditis and an atheromatous plaque from an aortic aneurysm. Primary thrombosis is associated with atherosclerosis and vasculitides, including conditions such as thromboangitis obliterans and polyarteritis nodosa. Primary thrombosis of the superior mesenteric veins may occur in association with factor V Leiden, portal hypertension, portal pyaemia and sickle cell disease and in women taking the oral contraceptive pill. A specific form of ‘non-occlusive mesenteric ischaemia’ may complicate critical illness, possibly due to alterations in splanchnic blood flow.
Successful treatment of sclerosing mesenteritis with tamoxifen monotherapy
Published in Baylor University Medical Center Proceedings, 2023
Lauren Zammerilla Westcott, Dallas Wolford, Taylor G. Maloney, Ronald C. Jones
Sclerosing mesenteritis is a rare idiopathic disorder of fat necrosis, inflammation, and fibrosis of the mesentery. The etiology of the condition remains largely speculative; however, case reports attribute etiology most commonly to prior abdominal trauma or surgery, followed by malignancy and autoimmune conditions.1 While the disease is often asymptomatic, a subset of patients develop complications from the mass effect on gastrointestinal, mesenteric, vascular, or lymphatic structures.2 A small percentage of patients may develop further complications such as small bowel obstruction, chylous ascites, or superior mesenteric vein thrombosis.2 The differential diagnosis is broad and includes any cause of mesenteric edema, hemorrhage, or infiltration with inflammatory or neoplastic cells.3
Evaluating the long-term survival benefits of high intensity focused ultrasound ablation for hepatocellular carcinoma with portal vein tumor thrombus: a single center retrospective study
Published in International Journal of Hyperthermia, 2022
Xing Chen, Yuhong Ma, Jun Zhang, Wei Yang, Chengbing Jin, Lifeng Ran, Hui Zhu, Jin Bai, Kun Zhou
Type I0: tumor thrombus formation is found under microscope.Type I: tumor thrombus involving segmental branches of portal vein or above.Type II: tumor thrombus involving the left and right branches of portal vein.Type III: tumor thrombus involving the main portal vein.Type IV: tumor thrombus involving the superior mesenteric vein.
Laparoscopic Pancreatectomy in Rats: The Development of an Experimental Model
Published in Journal of Investigative Surgery, 2022
José Marcus Raso Eulálio, Manoel Luiz Ferreira, Paulo César Silva, Juan Miguel Renteria, Andrei Ferreira Costa Nicolau, Thales Penna de Carvalho, Adrielle Rodas Fernandes, Julia Radicetti de Siqueira Paiva e Silva, Alberto Schanaider, José Eduardo Ferreira Manso
In summary, the pancreas of the rat has the following relevant anatomical landmarks:Considering its limits, the duodenum on the right, the stomach anteriorly, the spleen on the left, and the colon attached to the anterior face of the mesoduodenum.Considering its parenchyma, an intraperitoneal layer inside the omental pouch, with mobility from the spleen, duodenum and stomach.Considering its vascularization, the superior mesenteric vein and the superior mesenteric artery crosses the parenchyma posteriorly at the junction between the splenic and duodenal lobes receiving the arterial and venous tributaries. The splenic vessels follow the splenic lobe on its upper margin, from the hilum of the spleen to the root of the mesentery, where the splenic vein merges with the superior mesenteric vein to form the portal vein.Considering the ductal structure, the pancreatobiliary duct has its intrapancreatic path toward the second duodenal portion, directly receiving the lobular and lobar ducts. There is a major duodenal papilla, where the pancreatobiliary duct flows and several small ducts drains directly to the duodenum.