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The Excessive Gagging Reflex
Published in Eli Ilana, Oral Psychophysiology, 2020
The gagging reflex is defined as “the closing of the glottis and cessation of respiration evoked by stimulation of the sensory nerves of the pharynx or larynx either by the introduction of a solid or liquid or by the inspiration of irritating vapor.” The pharyngeal reflex is defined as “the contraction of the pharyngeal muscles associated with gagging,” and retching as “a straining, ineffective effort to vomit.”1
Expanding the phenotype of TARDBP mutation in a Tunisian family with clinical phenotype heterogeneity
Published in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2022
Imen Kacem, Ikram Sghaier, Nicola Ticozzi, Saloua Mrabet, Silvia Paverelli, Amina Nasri, Antonia Ratti, Mouna Ben Djebara, Amina Gargouri-Berrachid, Vincenzo Silani, Riadh Gouider
The III-5 case was 76-year-old with personal history of major depressive disorder at age of 58, presenting with rapid progressive worsening with slowness and rest tremor of the right-upper then lower limbs at an age of 75.5 year. Concurrently, she developed gait disorders with frequent forward falls. Year ago, she started to notice anterograde memory disorders. On examination, she had frontal syndrome with prehension behavior, asymmetric dopa-responsive tremo-akinetic-rigid parkinsonian syndrome prevailing on the right side and stimuli-sensitive myoclonus of the upper limbs. She had also brisk tendon reflexes, bilateral Babinski sign and bulbar syndrome with hypotonic dysarthria and decreased pharyngeal reflex. Neuropsychological assessment revealed cognitive impairment, marked dysexecutive syndrome, attention and retrieval deficits. Brain imaging showed frontal and temporal lobe atrophy with relative preservation of posterior areas (Figure 2(C) and Table 1).
A clinical report of intracranial granulocytic sarcoma and a literature review
Published in International Journal of Neuroscience, 2022
Hao Cheng, Guangfu Di, Wanan Gao, Zhao Chenhui, Xiaochun Jiang
This patient was a 53-year-old male with congenital deaf-muteness, who complained of pain in the left cheek for 2 months with aggravation for 10 days. The neurologic examination showed the patient was conscious, poor mental status, bilateral anisocoria (left pupil was 4.0 mm while the right pupil was 3.0 mm, both light reactions were sensitive). The patient had a hypophasis with left corneal reflex diminished. He suffered a pressing pain on the left cheek, his jaw and tongue tilted to the left when he opened mouth, and the left pharyngeal reflex was declined. He had a soft neck, normal limb muscular strength, normal deep and superficial sensations. Babinski sign was negative in both lower extremities. Babinski sign was negative in both lower extremities. The patient was in good health before the visit and had no history of leukemia.
Endoscopic observation of pharyngeal mucosal suture healing process after total laryngectomy: case series
Published in Acta Oto-Laryngologica, 2023
Shin Matsumoto, Masahiro Nakayama, Keitaro Fujii, Masahiro Adachi, Yoshihide Shima, Keiji Tabuchi
The pharyngeal reflex observed during endoscopy may strain the surgical suture. Nasal endoscopy, which is routinely performed in otolaryngology, is an empirically safe and cost-effective procedure; even though there are few reports documenting its safety. A previous study has shown that when the larynx is touched with the endoscope to assess swallowing function, pressure is applied to the endoscope, resulting in laryngeal adductor reflex triggering swallowing, coughing, and vomiting reflexes [20]. All patients in the present series did not exhibit excessive pharyngeal reflexes. However, frequent postoperative endoscopies may be avoided in patients displaying strong pharyngeal reflexes during preoperative endoscopies.