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Geographic Tongue
Published in Charles Theisler, Adjuvant Medical Care, 2023
Geographic tongue is characterized by irregular patches on the surface of the tongue. This gives the tongue a map-like appearance. It is caused by a loss of the tiny, finger-like projections, called papillae, on the tongue. Geographic tongue usually has no symptoms. Occasionally geographic tongue may cause a burning or smarting sensation of the tongue causing patients to seek treatment. In most cases, there is no need for treatment.
Oral Diseases
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Marcia Ramos-e-Silva, José Wilson Accioly Filho, Sueli Carneiro, Nurimar Conceição Fernandes
Clinical presentation: The tongue shows longitudinal, transverse, or oblique fissures in part or on its entire dorsal surface. Food debris can be lodged in these fissures, causing or contributing to inflammation and a feeling of discomfort.
Hip Pain
Published in Benjamin Apichai, Chinese Medicine for Lower Body Pain, 2021
Damp heat type: There is a warm sensation at the painful area, and it is aggravated during hot days or rainy days. The pain could be less after movements. Urine is dark. The tongue has a yellow greasy coating. The pulse is slippery and rapid.
Critical roles of adherens junctions in diseases of the oral mucosa
Published in Tissue Barriers, 2023
Christina Kingsley, Antonis Kourtidis
Situated in the central portion of the oral cavity, the tongue is important in mastication, or chewing to form a bolus of food, and also assists in swallowing. The tongue consists of stratified squamous epithelium and is attached to the floor of the mouth via a folded structure, called the frenulum.4 The ventral portion of the tongue consists of stratified squamous, non-keratinized epithelium, while the dorsum of the tongue is covered by a specialized mucosa that can be either keratinized or non-keratinized2 (Figure 1). Taste bud papillae are found predominantly on the tongue and palate. There are three types of papillae: a) fungiform located on the anterior portion; b) circumvallate, which are located on the posterior part of the tongue; and c) foliate papillae located on the lateral sides of the tongue.5
Advanced-stage tongue squamous cell carcinoma: a machine learning model for risk stratification and treatment planning
Published in Acta Oto-Laryngologica, 2023
Rasheed Omobolaji Alabi, Mohammed Elmusrati, Ilmo Leivo, Alhadi Almangush, Antti A. Mäkitie
Remarkably, the advanced-stage tongue cancer is characterized by a worse prognosis at diagnosis. By standard, the recommended treatment for late-stage tongue cancer is surgery followed by postoperative radiotherapy [11]. This recommendation was corroborated in this study as it was observed that patients that received Sx + RT showed a better chance of OS (Figures 3 and 4). Similarly, the European Organization for Research and Treatment of Cancer (EORTC) and Radiation Therapy Oncology Group (RTOG) has suggested the use of concurrent chemotherapy [11]. This latter suggestion was also supported by the finding in this study specifically for advanced-stage patients with T3N1 disease where having received Sx + CRT showed promising results in terms of 5-year OS [11] (Figure 5). With the current radiotherapy (RT) techniques such as the intensity-modulated radiotherapy treatment (IMRT), this treatment modality may be poised to be a vibrant treatment approach for advanced-stage tongue cancer. Post-operative chemoradiotherapy is typically indicated for patients with multiple metastases, extra nodal spread, or positive surgical margin.
Microbial characteristics across different tongue coating types in a healthy population
Published in Journal of Oral Microbiology, 2021
Hairong Chen, Qingwei Li, Min Li, Sheng Liu, Chensi Yao, Zixiong Wang, Zhuoya Zhao, Ping Liu, Fan Yang, Xinjian Li, Jun Wang, Yixin Zeng, Xiaolin Tong
The reasons behind different tongue coating types enriched by distinctive marker microbes may partly be attributed to different salivary flow rates [53]. It has been reported that more frequent self-reported symptoms of low salivary flow rate was associated with higher abundance of tongue coating P. melaninogenica [54]. Consistently, we demonstrated that the Y-thick greasy group had significantly less salivary secretions (Supplementary Figure 3) and that P. melaninogenica was distinguishable as the characteristic marker microbe (Table 2). However, although the salivary flow rate seems to decline in the W-thick greasy group (Supplementary Figure 3), the characterized marker microbe, M. micronuciformis (Table 2), is not reported to be associated with impaired salivary secretion [55]. Therefore, how the salivary flow rate affects each group and, in particular, different marker species requires further studies and interpretations.