Famotidine

Famotidine

Famotidine is a medication that works by blocking histamine H2-receptors in the body, making it a competitive histamine H2-receptor antagonist. It is commonly used to treat gastrointestinal disorders such as gastric or duodenal ulcer, GERD, and pathological hypersecretory conditions. Additionally, famotidine is used for the prevention and treatment of stomach and intestinal ulcers.From: Hazardous Chemicals [2019], Handbook of Terahertz Technologies [2019]

Compressed Solids Formulations

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Published in Sarfaraz K. Niazi, Handbook of Pharmaceutical Manufacturing Formulations, Third Edition, 2019

Sarfaraz K. Niazi

Each tablet for oral administration contains either 20 or 40 mg of famotidine. The inactive ingredients are hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxides, magnesium stearate, microcrystalline cellulose, starch, talc, and titanium dioxide. Each Pepcid RPD orally disintegrating tablet for oral administration contains either 20 mg or 40 mg of famotidine and the following inactive ingredients: aspartame, mint flavor, gelatin, mannitol, red ferric oxide, and xanthan gum.

Fabrication of Ag-doped ZnO by mechanochemical combustion method and their application into photocatalytic Famotidine degradation

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Journal Information

Published in Journal of Environmental Science and Health, Part A, 2019

Md. Ashraful Islam Molla, Mai Furukawa, Ikki Tateishi, Hideyuki Katsumata, Satoshi Kaneco

The target molecule Famotidine (FMT, Fig. 1) for degradation is a histamine H2-receptor antagonist, which may induce altered mental status in older adults and cause chronic kidney disease.[9] It is reported that average concentrations of FMT include 25 ng/L in drug production facilities and 94 ng/L in hospitals wastewater discharges.[10] Due to the presence of amine, thiazole and thioether groups in FMT structure, it displays excellent complexing properties.[11] FMT slowly hydrolyzes in aqueous solutions (pKa = 6.7) and can be considered as a persistent contaminant.[12] Hence, it is very important to develop the treatment technology for FMT urgently to complete removal from wastewaters, preventing its hazardous accumulation in the future.

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Compressed Solids Formulations

Fabrication of Ag-doped ZnO by mechanochemical combustion method and their application into photocatalytic Famotidine degradation