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Microbial Biofilms
Published in Bakrudeen Ali Ahmed Abdul, Microbial Biofilms, 2020
UTIs are quite a known type of infection, especially present in the lives of women. Namely, women have a likelihood of suffering from UTIs at least once in their lifetime; the actual percentage of experiencing is approximately 40%–60% (“Urinary Tract Infection (UTI)—Symptoms and Causes” 2019). The chances of creating an all-encompassing treatment strategy for individuals who suffer from complicated UTIs are fairly slim due to the myriad of complications that may or may not arise during the period of infection (Desforges, Stamm, and Hooton 1993). An incessant infection that plagues the medical community isinfections which affect the human urinary system. One way to fight off these infections as mentioned has been with the use of antibiotics (Schmiemann et al. 2010). However, scientific findings have led to the deduction that certain cells of biofilm communities have a greater aversion and resistance to antibiotics, especially when making a comparison with various planktonic bacterial cells (Delcaru et al. 2016, Tabibian et al. 2008)
Elaeocarpus tectorius and its Therapeutic Potential against Selected Urinary Tract Infection Pathogens
Published in Parimelazhagan Thangaraj, Phytomedicine, 2020
M. Ashwini Lydia, Suman Thamburaj, Gayathri Jagadeesan, Gayathri Nataraj, Kasipandi Muniyandi, Saikumar Sathyanarayanan, Parimelazhagan Thangaraj
Urinary tract infections are the most common microbial infection occurring in the urinary tract. Frequently, women suffer from this infection during menstruation and pregnancy. So it occurs more predominantly in women than men. It is approximated that about 35% of healthy women suffer with UTIs at various stages in their life. About 5% of women each year experience a UTI with the problems of painful urination (dysuria) and frequency (Nabbugodi et al. 2015). The major causative agent for a UTI is the uropathogenic bacteria E. coli (Abraham and Miao 2015). The causative agents for community-acquired urinary tract infections are mostly the uropathogenic Escherichia coli from the gut of about 80%–85%, then Pseudomonas aeruginosa with about 11%, Staphylococcus aureus with 5%–10%, followed by Candida albicans the yeast fungal pathogen as 9%, and they were the test pathogens used for the study (Nicolle 2008; Salvatore et al. 2011). They act as hosts for the frequent causes of urinary infections. The increasing multidrug resistance of UTI-causing microbial strains has made the treatment of UTIs difficult and has led to the greater use of costly broad-spectrum synthetic drugs (Tenney et al. 2018). This problem needs an improved effort, which has resulted in the search for valuable microbicide agents to be used against UTIs that are caused by pathogenic microorganisms resistant to current antibiotic drugs (Toner et al. 2016).
Glossary of scientific and technical terms in bioengineering and biological engineering
Published in Megh R. Goyal, Scientific and Technical Terms in Bioengineering and Biological Engineering, 2018
Urinary tract infection (UTI) is an infection that occurs in the urinary tract, often caused by bacteria such as Escherichia coli. A UTI often causes frequent urination, pain and burning when urinating, and blood in the urine.
Co(II)-coordination polymer: treatment and testing values on calculus of ureter by inhibiting the growth of urinary tract pathogens
Published in Inorganic and Nano-Metal Chemistry, 2022
Tao Yue, Yan Jing, Lei Tan, Rui Xue
The prerequisite for the formation of infectious stones is persistent urinary tract infection. Among the pathogens that cause urinary tract infections, about 1/3 are caused by microorganisms (fungi, bacteria, mycoplasma) that produce urease, especially the bacteria.[1] The most common are Proteus, Klebsiella, Pseudomonas Monas and Staphylococcus.[2] Urinary tract infection bacteria are mainly Gram-negative bacilli, with Escherichia coli and Klebsiella pneumoniae ranking first and second separately.[3] Thus, in this present research, we aimed to develop new candidates for the treatment of calculus of ureter through inhibiting the growth of urinary tract pathogens.
Does antimicrobial coating and impregnation of urinary catheters prevent catheter-associated urinary tract infection? A review of clinical and preclinical studies
Published in Expert Review of Medical Devices, 2019
Aneela Majeed, Fnu Sagar, Azka Latif, Hamza Hassan, Ahmad Iftikhar, Rabih O. Darouiche, Mayar Al Mohajer
Catheter-associated urinary tract infection (CAUTI) is one of the most common nosocomial infections in hospitals, accounting for 36% of all health care-associated infections [1]. Untreated urinary tract infection can lead to local or systemic symptoms, increases morbidity, predisposes patients to sepsis, harbors drug resistance, adds to increased health care costs, and possibly leads to death [2–4]. The leading risk factor for bacteriuria is the duration of catheterization, as each additional day of catheterization increases the prevalence of bacteriuria by 3% to 10% [5]. The proposed methods to prevent CAUTI include shortening the duration of catheter use [6] and using sterile equipment and aseptic techniques during catheter insertion [7]. Other alternative methods include the use of condom catheters and intermittent straight catheterization [3], prevention of intraluminal and extraluminal encrustations [8], and modification of catheter surfaces with antimicrobial coating or impregnation [9]. The main objective of this review article was to address the role of newer antimicrobial coating agents evaluated in clinical and preclinical studies in the prevention of CAUTI. We also summarized the available data on biofilm reduction with the use of these coating agents and the degree of microbial growth inhibition from in vitro studies.
Evaluation of antibacterial efficacy of sulfur nanoparticles alone and in combination with antibiotics against multidrug-resistant uropathogenic bacteria
Published in Journal of Environmental Science and Health, Part A, 2019
Priti Paralikar, Avinash P. Ingle, Vaibhav Tiwari, Patrycja Golinska, Hanna Dahm, Mahendra Rai
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range of pathogens, both Gram-negative and Gram-positive bacteria, as well as by certain fungi.[1] However, the most common pathogens responsible for UTIs are Escherichia coli (70–80% of UTIs), Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis and Staphylococcus saprophyticus.[1–3] UTIs affect 150 million people each year worldwide occurring in every age group of both genders, but particularly in female population.[4–6] It has been reported that UTI accounts for about 8.3 million visits to doctors per year.[7–9] UTIs still remain a challenge for medicine because of poor diagnosis and reason of hospital acquired infections.[10]