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Quantum Mechanics of Wound Healing: Nano-bio Interface of Wound Bed and Wound Dressing
Published in Cherry Bhargava, Amit Sachdeva, Pardeep Kumar Sharma, Smart Nanotechnology with Applications, 2020
Garima Shandilya, Kirtan Tarwadi, Sachin Chavan
Nanotechnology offers potential applications and cutting-edge solutions to design and engineer efficient biomedical approaches to solve medical complications. A number of nanomaterials have been developed and proved to have remarkable applications in wound care and healing. Nanostructures and varied shaped nanoparticles (rod shape, sphere, triangular, core-shell) are incredible components that aim to reinforce therapeutic delivery of growth factors, antimicrobial agents, gene therapy vectors and others to the wound. The most explored approaches for management of wounds invoke development of nano-devices for (i) inflammation control; (ii) cellular proliferation and re-epithelization; and (iii) tissue remodeling.
A review on the recent progress, opportunities, and challenges of 4D printing and bioprinting in regenerative medicine
Published in Journal of Biomaterials Science, Polymer Edition, 2023
Parvin Pourmasoumi, Armaghan Moghaddam, Saba Nemati Mahand, Fatemeh Heidari, Zahra Salehi Moghaddam, Mohammad Arjmand, Ines Kühnert, Benjamin Kruppke, Hans-Peter Wiesmann, Hossein Ali Khonakdar
The smart structures produced by 4 D printing can make transformations by themselves when exposed to stimuli. This property, in other words, the capability of post-production transformation, gives 4 D printed materials a significant advantage from the product dimensions point of view compared to 4 D printed materials, as in a 3 D printer, the product's dimensions depend on the size of the printer. A 4 D printer can create a much larger construct than the printer’s dimensional limitations. In addition to dimensions, and particularly for biomedical applications, 4 D printing can potentially benefit many different areas such as tissue regeneration, medical device fabrication, drug delivery, and medical diagnosis. In the case of tissue regeneration, the ultimate goal is to engineer functional scaffolds to replace diseased or injured tissues. Ideally, the engineered materials should possess bio-mimicking features and bio-responsiveness to assist tissue remodeling. 4 D printing technology provides a good platform for fabricating scaffolds with intricate designs and controlled changes in properties over time.