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Role of Microfluidics-Based Point-of-Care Testing (POCT) for Clinical Applications
Published in Raju Khan, Chetna Dhand, S. K. Sanghi, Shabi Thankaraj Salammal, A. B. P. Mishra, Advanced Microfluidics-Based Point-of-Care Diagnostics, 2022
Arpana Parihar, Dipesh Singh Parihar, Pushpesh Ranjan, Raju Khan
Multiple organ failure, shock, and death can all result from sepsis (mortality increases by 7.6% for every hour spent waiting for antibiotics in septic shock, for example) [58]. As a result, early, precise, and timely diagnosis and treatment of sepsis are critical. Current diagnostic and therapeutic approaches, such as physical examination, blood and urine analysis, and molecular diagnostic methods, can be suboptimal if not integrated. Furthermore, due to disadvantages such as the high sample volume required and the time and labor-intensive nature of these methods, they do not meet the ASSURED requirements [59].
Transfer learning-based CNN diagnostic framework for diagnosis of COVID-19 from lung CT images
Published in The Imaging Science Journal, 2022
R. Keerthana, Angelin Gladston, H. Khanna Nehemiah
The main symptoms presented by suspected infections include respiratory distress, fever, cough, shortness of breath or difficulty in breathing, chills, repeated shaking with chills, muscle pain, headache, sore throat, and loss of taste or smell. In some patients, particularly the elderly and others with chronic health conditions, these symptoms can develop into pneumonia, chest tightness, and chest pain. Development into pneumonia could be observed from the lesions that are mainly distributed in the peripheral portion of the lung on chest Computed Tomography (CT) imaging. The virus may also cause pneumonia in more aggressive infections. Besides pneumonia, the infection can lead to severe acute respiratory syndrome, septic shock, multiple-organ failure, and death [6]. Studies show that men (about 60%) were more affected than women (about 40%) and there were no significant death rates in children younger than nine years old [2]. Despite being developed, many first-world countries have been facing a collapse of the healthcare system owing to escalating demand for intensive care units simultaneously [7,8].