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Assessment of Quercetin Isolated from Enicostemma Littorale Against Few Cancer Targets: An in Silico Approach
Published in A. K. Haghi, Ana Cristina Faria Ribeiro, Lionello Pogliani, Devrim Balköse, Francisco Torrens, Omari V. Mukbaniani, Applied Chemistry and Chemical Engineering, 2017
Renal cell carcinoma (RCC, also known as hypernephroma) is a kidney cancer that originates in the lining of the proximal convoluted tubule, the very small tubes in the kidney that filter the blood and remove waste products. RCC is the most common type of kidney cancer in adults, responsible for approximately 80% of cases.55 It is also known to be the most lethal of all the genitourinary tumors. Initial treatment is most commonly a radical or partial nephrectomy and remains the mainstay of curative treatment.63 Where the tumor is confined to the renal parenchyma, 5-year survival rate is 60-70%, but this is lowered considerably where metastases have spread. It is resistant to radiation therapy and chemotherapy, although some cases respond to immunotherapy. Targeted cancer therapies such as sunitinib, temsirolimus, bevacizumab, interferon-alpha, and possibly sorafenib have improved the outlook for RCC (progression-free survival), although they have not yet demonstrated improved survival. It is reported that in a population of 58,240 (35,370 men and 22,870 women) around 13,040 men and women died of kidney and renal cancer.33
Urinary system
Published in A Stewart Whitley, Jan Dodgeon, Angela Meadows, Jane Cullingworth, Ken Holmes, Marcus Jackson, Graham Hoadley, Randeep Kumar Kulshrestha, Clark’s Procedures in Diagnostic Imaging: A System-Based Approach, 2020
A Stewart Whitley, Jan Dodgeon, Angela Meadows, Jane Cullingworth, Ken Holmes, Marcus Jackson, Graham Hoadley, Randeep Kumar Kulshrestha
MRI is also the gold standard for assessing renal vein thrombosis along with renal venography and CT. MRI can be used in the assessment of suspected renal cell carcinoma, where CT and ultrasound are non-diagnostic or where radiographic contrast is contraindicated.
A PPM-based UNet for Tumour and Kidney Segmentation in CTScans
Published in Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 2023
Marcus Vinicius S. L. Oliveira, Caio E. F. Matos, Geraldo Braz Júnior, Anselmo Cardoso de Paiva, João D. Sousa de Almeida, Gabriel J. S. Costa, Matheus L. L. Bessa, Mario P. Freitas Filho
Specifically, kidney cancer, also known as kidney cancer or renal cell carcinoma, is among the 14 most common types of cancer. The kidneys consist of two organs in the urinary tract located in the posterior part of the abdomen. Their upper extremities are located at the level of the costal arches, close to the 10th and 12th thoracic ribs. This organ is responsible for eliminating toxins from the blood through a filtering system, regulating blood pressure and controlling body fluids (Sb 2022). Kidney cancer had more than 430,000 new cases in 2020 (WHO 2020b). Of these, approximately 271,000 were men and 160,000 were women. This pathology is the third most frequent concerning the genitourinary system (genital and urinary organs), representing about 3% of cancers in adults, and its incidence is 50% higher in men than in women.