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Microbial Biotechnology
Published in Nwadiuto (Diuto) Esiobu, James Chukwuma Ogbonna, Charles Oluwaseun Adetunji, Olawole O. Obembe, Ifeoma Maureen Ezeonu, Abdulrazak B. Ibrahim, Benjamin Ewa Ubi, Microbiomes and Emerging Applications, 2022
Olawole O. Obembe, Nwadiuto (Diuto) Esiobu, O. S. Aworunse, Nneka R. Agbakoba
RA is a chronic autoimmune disease characterized by inflammation and joints pain with various types of systemic involvement. A significant feature of RA is the destruction of bones and cartilage, which may eventually lead to disability. The disease occurs more in women than in men (Xu et al., 2019). The genetic background of the patient plays a vital role in the pathogenesis of the disease. Other risk factors, such as infection and tobacco use, have shown strong evidence for the pathogenesis of the disease. Interaction of metabolites from gut microbiota with the host immune system also leads to the pathogenesis of RA.
Hypersensitivity pneumonitis in a slaughterhouse worker: A case report
Published in Archives of Environmental & Occupational Health, 2022
Elena Vasileiou, Paschalis Ntolios, Paschalis Steiropoulos, Theodoros Constantinidis, Evangelia Nena
Working in a slaughterhouse involves exposure to a significant number of biological hazards. A broad range of contaminants, such as bacteria and fungi, can be released during different processes of slaughtering while removing head hair or cleaning the colon of the animals. These contaminants can be the major cause of non-allergic inflammation in the respiratory system.1,2 Indeed, various respiratory disorders have been previously reported among sheep-shearing workers, exposed to microbial air contamination, namely, chronic bronchitis, asthma, and hypersensitivity pneumonitis (HP).3 The latter, also called extrinsic allergic alveolitis (EAA), is an interstitial lung disease (ILD) with a wide spectrum of clinical manifestations, as well as a varying intensity and natural history. Occupational and environmental exposures play a major role in its pathogenesis.