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An Advanced Insulin Bolus Calculator for Type 1 Diabetes
Published in Pietro Salvo, Miguel Hernandez-Silveira, Krzysztof Iniewski, Wireless Medical Systems and Algorithms, 2017
Peter Pesl, Pau Herrero, Monika Reddy, Maria Xenou, Nick Oliver, Pantelis Georgiou
Large intervention trials performed in the European Union [2] and the United States [3] showed how tight glycemic control avoiding hyperglycemia could prevent long-term complications such as microvascular (retinopathy, nephropathy, and neuropathy) and macrovascular disease (cardiovascular disease, stroke, and peripheral vascular disease). Such complications are reported to place a heavy burden on health services [4]. These trials also reported the associated risk of induced hypoglycemia (low blood glucose) that underscores the crucial need for exact and timely insulin dosage [5]. Severe or prolonged hypoglycemia is a major concern for people with diabetes and can result in seizures, cardiac arrhythmias, and the “dead-in-bed” syndrome.
Biologically active mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) as potential antimalarial, antidibetic and anticancer agents
Published in Inorganic and Nano-Metal Chemistry, 2022
Vikas D. Ragole, Dnyaneshwar S. Wankhede, Sonaji V. Gayakwad
Cancer, diabetes and malaria are serious health concerns in countries like India and hence the primary targets of chemistry research. Cancer is a group of diseases involving abnormal cell growth which can spread to other body parts and caused deaths of millions of people throughout the world. The platinum based complex ‘Cisplatin’ owing to its anticancer activities has motivated worldwide researchers to work in this area which has produced large number of molecules. Still the research is ongoing in order to find different metal complexes with less side effects and similar or better cytotoxicity.[1] Diabetes resulting from insulin deficiency or insulin resistance is a serious chronic disorder around the world.[2–4] Two main types disease viz. type 1 (insulin dependent) and type 2 (non-insulin dependent) diabetes are known. Although various drugs are available in the market at present, the complications involved such as kidney failure, micro-and macrovascular disease, retinopathy, neuropathy and atherosclerosis has created an urgent need for the search of orally active drugs.[2–4] Malaria is one of the most infectious diseases affecting to health and developmental growth of developing countries. It is present in 91 countries, mostly in tropical and subtropical regions and the incidence of malaria becoming serious owing to globalization in the world.[5,6] The antimalarial potential of coordination compounds is well established and the research is still continued.