Glut3

Glut3

Infection and Inflammation

Published in Michael Ljungberg, Handbook of Nuclear Medicine and Molecular Imaging for Physicists, 2022

Erik H. J. G. Aarntzen, Andor W. J. M. Glaudemans

18F-fluorodeoxyglucose (18F-2’-fluoro-2’-deoxyglucose or 18F-FDG) is an analog of glucose and is taken up by living cells via cell membrane glucose transporters and subsequently phosphorylated with hexokinase inside most cells. Immune cells involved in infection and inflammation, especially activated neutrophils and the monocyte/macrophage lineages, express high levels of glucose transporters GLUT1 and GLUT3, and hexokinase activity [65].

Exenatide promotes the autophagic function in the diabetic hippocampus: a review

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Journal Information

Published in Egyptian Journal of Basic and Applied Sciences, 2022

Eman Mohammed Elsaeed, Ahmed Gamal Abdelghafour Hamad, Omnia S. Erfan, Mona A. El-Shahat, Fathy Abd Elghany Ebrahim

Additionally, the autophagic impairment may contribute to the development of insulin resistance, as the accumulation of dysfunctional mitochondria results in elevated levels of reactive oxygen species (ROS) that overwhelm the cytoprotective capacity of autophagy, which is implicated as one of the mechanisms of insulin resistance [31]. Insulin resistance can develop in the neural tissue as well. Indeed, the neural tissue is insulin-independent for containing the glucose transporters GLUT1 and GLUT3, but it is insulin-responsive, as insulin receptors are widely expressed in the brain [3].

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Infection and Inflammation

Exenatide promotes the autophagic function in the diabetic hippocampus: a review