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EdgeRunner: a novel shape-based pipeline for tumours analysis and characterisation
Published in Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 2018
Fernando Yepes-Calderon, Darryl Hwang, Rebecca Johnson, Desai Bhushan, Niharika Gajawelli, Steven Yong, Brian Quinn, Felix Yap, Inderbir Gill, Natasha Lepore, Vinay Duddalwar
In the CCRC type of mass, the cancer cells originate from the proximal tubule and are characterised by malignant epithelial cells with clear cytoplasms, which exhibit acinar or sarcomatoid growth pattern. On the other hand, the RO mass, originates from the cortical collecting duct and is a benign neoplasm of the kidney composed of cells with mitochondria-rich eosinophilic cytoplasm. These two types of renal tumours are often indistinguishable of routine visual analysis of the imaging data.