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Multimodal Medical Image Fusion in NSCT Domain
Published in Ayman El-Baz, Jasjit S. Suri, Big Data in Multimodal Medical Imaging, 2019
Gaurav Bhatnagar, Zheng Liu, Q.M. Jonathan Wu
The efficiency of the proposed scheme is further assessed using two more clinical cases where X-ray and bone scintigraphy medical imaging modalities are used. The damage in the bones such as fracture or dislocated joint or foreign object location can primarily be determined using an X-ray. In contrast, certain bone abnormalities such as bone inflammation (bone pain due to a fracture), light fractures, bone damage detection (due to certain infections) and cancer of the bone can be identified by bone scintigraphy [60]. These abnormalities may not be visible in X-rays. The bone scintigraphy result is generally perceived as hot and cold spots. Hot spots usually indicate the affected area in the bones, and the perfect location can be obtained by combining X-rays with bone scintigraphy.
Musculoskeletal system
Published in David A Lisle, Imaging for Students, 2012
Bone scintigraphy, commonly known as ‘bone scan’, is performed with diphosphonate-based radiopharmaceuticals such as 99mTc-MDP. Bone scintigraphy is highly sensitive and therefore able to demonstrate pathologies such as subtle undisplaced fractures, stress fractures and osteomyelitis prior to radiographic changes becoming apparent. Scintigraphy is also able to image the entire skeleton and is therefore the investigation of choice for screening for skeletal metastases and other multifocal tumours. The commonest exception to this is multiple myeloma, which may be difficult to appreciate on scintigraphy. Skeletal survey (radiographs of the entire skeleton) or whole body MRI are usually indicated to assess the extent of multiple myeloma.
Nuclear Medicine in Oncology
Published in Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 2018
Carla Oliveira, Rui Parafita, Ana Canudo, Joana Correia Castanheira, Durval C. Costa
There are several clinical indications for bone scintigraphy, since all the inductor processes of osteoblastic activity (such as infections and inflammatory pathologies) may have a scintigraphic translation (which, in fact, explains the low specificity of this exam). However, one of its main clinical applications is, undoubtedly, screening for bone metastases. Being a whole body and highly sensitive study (sensitivity values of around 95%) (Brenner 2012), bone scintigraphy is a first-order exam in bone staging and restaging of malignant tumours with a usual bone metastases pattern of the osteoblastic or mixed type, as well as in monitoring the response of bone metastases to treatment.