Anesthetic

Anesthetic

Anesthetic refers to a substance or drug that is used to block pain and other sensations during surgical procedures. It can be administered locally to block the transmission of painful stimuli to the brain or through general anesthesia, which renders the patient unconscious and paralyzes their skeletal muscles. Anesthetics are commonly used by doctors and dentists to manage acute and chronic pain in postoperative patients.From: Practical Guide to Industrial Safety [2018], Near-infrared triggered on-demand local anesthesia using a jammed microgels system [2020], Medical Devices and Systems [2019]

Diagnostic Devices

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Published in Laurence J. Street, Introduction to Biomedical Engineering Technology, 2016

Laurence J. Street

General anesthetics such as isoflurane, sevoflurane, and desflurane act by blocking ion channels in the nervous system, thus blocking pain and producing unconsciousness. Anesthetic machines are described in Chapter 7.

Near-infrared triggered on-demand local anesthesia using a jammed microgels system

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Journal Information

Published in Journal of Biomaterials Science, Polymer Edition, 2020

Qiying Pang, Jia Zhao, Shuchi Zhang, Xiaoqing Zhang

Patients suffering from postoperative or chronic pain usually live with low quality of life [1]. They have to be tethered to an external device or be maintained as inpatients. Efficient postoperative pain management is important for improving quality of life, and lowering the risk of developing chronic pain after surgery [2,3]. Local anesthetics block the transmission of painful stimuli to the brain, and have been applied in the field of postoperative analgesia to manage acute and chronic pain [4,5]. However, their cardio and neurotoxicity, as well as short half-life stress the need for developing implantable devices for tailored local drug release [6,7].

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Diagnostic Devices

Near-infrared triggered on-demand local anesthesia using a jammed microgels system