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Unexplained Fever Associated With Cutaneous Manifestations
Published in Benedict Isaac, Serge Kernbaum, Michael Burke, Unexplained Fever, 2019
In Henoch-Schonlein purpura (syn. anaphylactoid purpura), the fever may precede, together with other prodromal symptoms, the papular, urticarial, and purpuric lesions, associated with polyarthralgia and abdominal symptoms.
Noninfectious Pulmonary Manifestations of Renal Disease In Children
Published in Lourdes R. Laraya-Cuasay, Walter T. Hughes, Interstitial Lung Diseases in Children, 2019
Stephen T. Lawless, H. Jorge Baluarte
Henoch-Schonlein purpura (HSP) or anaphylactoid purpura is a leukoclastic vasculitis of the small blood vessels of the skin, kidney, gastrointestinal tract, lungs, liver, heart, and spleen. There is a nonthrombocytopenic purpuric rash on the lower extremities and buttocks with joint swelling, diarrhea, hematochezia associated with colicky abdominal pain, and nephritis. It occurs 1 to 3 weeks after an upper respiratory infection. Rarely, pulmonary hemorrhage, perihilar patchy infiltrates, reticulonodular changes and pneumonic processes may be present.24 Rapidly progressive glomerulonephritis may follow. If chronic renal failure results, signs of uremic pneumonitis appear. IgA deposits in dermal capillaries or renal biopsy support the diagnosis of HSP.
Altered resting-state cerebellar-cerebral functional connectivity in patients with end-stage renal disease
Published in Renal Failure, 2023
Jie Fang, Yingying Miao, Fan Zou, Yarui Liu, Jiangle Zuo, Xiangming Qi, Haibao Wang
Thirty-seven ESRD patients with peritoneal dialysis were recruited from The First Affiliated Hospital of Anhui Medical University, Hefei, China. The etiology of the ESRD was as follows: chronic glomerulonephritis (n = 24), IgA nephropathy (n = 4), polycystic kidney (n = 4), lupus nephritis (n = 2), anaphylactoid purpura (n = 2), nephrotic syndrome (n = 1). The recruitment criteria for ESRD patients were as follows: dialysis duration was not less than three months in patients; aged 20–65 years; patients with stable disease without dyspnea, heart failure, nausea, fatigue, or other symptoms. Exclusion criteria were the presence of craniocerebral trauma, tumor, stroke, or other neurological diseases, history of alcohol or drug abuse, previous history of neuropsychiatric illness, central nervous medication is taken during the past 3 months, head movement translation or rotation > 2.0 mm or 2.0° during MRI scan, or the presence of contraindications to MRI examination. We recruited 35 age- and gender-matched control subjects using the same exclusion criteria as that for the patients.
Infection-related hospitalization after intensive immunosuppressive therapy among lupus nephritis and ANCA glomerulonephritis patients
Published in Renal Failure, 2020
Peihong Yin, Jianbo Li, Qiong Wen, Yagui Qiu, Wenyi Liang, Junxian Wang, Jing Yu, Zhong Zhong, Xiao Yang, Xueqing Yu, Qing Ye, Fengxian Huang
This was a retrospective study. All inpatients diagnosed with LN or ANCA glomerulonephritis at the First Affiliated Hospital of Sun Yat-sen University from 1 January 2005 to 31 December 2014 were screened. All of the selected patients fulfilled the following inclusion criteria: ① age ≥18 years; ② intensive immunosuppressive therapy initiated at our hospital; and ③ regular follow-up. Intensive immunosuppressive therapy was defined as therapy with glucocorticoids and immunosuppressants [18]. Regular follow-up means that patients visited specialist physicians regularly every 1–3 months. Patients who had already received immunosuppressive therapy at another medical institution before admission to our hospital, were in poor compliance, or had a history of renal replacement therapy were excluded. Poor compliance was defined when medical records (electrical or manual) were unavailable due to telephone-confirmed irregular follow-up of patients. All LN patients fulfilled the 1997 revised SLE classification criteria of the American College of Rheumatology with renal damage [19]. All ANCA glomerulonephritis patients met the criteria for ANCA-associated vasculitis outlined by the Chapel Hill Consensus Conference; ANCA glomerulonephritis patients with secondary SLE, rheumatoid arthritis, anaphylactoid purpura, drug abuse, or infection were excluded from the analysis [20]. This study was approved by the ethics committee of the First Affiliated Hospital of Sun Yat-sen University. Informed consent was waived by the committee because of the retrospective nature of the study.
Tamibarotene inhibit the accumulation of fibrocyte and alleviate renal fibrosis by IL-17A
Published in Renal Failure, 2020
Lixi Li, Ran Luo, Yi Yang, Yichun Cheng, Shuwang Ge, Gang Xu
Eighty-eight patients (51 men and 37 women; mean age = 36.78 ± 1.09 years) who underwent kidney biopsy and pathologic diagnosis of IgAN between January 2012 and December 2014 at the Tongji Hospital were enrolled in the study. Their blood samples were obtained at the time of diagnosis. The exclusion criteria included age <18 years and secondary etiologies of IgAN (anaphylactoid purpura and liver cirrhosis among others). Our protocol was approved by the institutional review board or ethics committee at Tongji hospital. Written informed consent was obtained from all patients.