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Education and support for fathers
Published in Mary L. Nolan, Parent Education for the Critical 1000 Days, 2020
Educators can stimulate discussion about the possible difficulties of becoming a father and encourage disclosure of problems early on (Domoney et al., 2013). Sharing first-hand accounts can provide insight into fathers’ experiences of depression and help tackle stigma: Work was almost impossible now. I found myself starting to cry without even feeling it creeping up on me. It was the worst I could remember feeling … my mental health was sliding … I just wanted to do nothing, and that made me feel guilty. I started to avoid people, stopped going to training sessions as much as I should, and started to eat rubbish food. I was coming apart. I felt like I couldn’t even express myself or make simple decisions. Just carrying on normal conversations was a struggle, never mind trying to close a sale. I wasn’t just in a rut. I was about to lose my job, my company car, my wage.(Williams 2018:88–89)
Clinical Issues and Case Histories
Published in Albert A. Kurland, S. Joseph Mulé, Psychiatric Aspects of Opiate Dependence, 2019
Albert A. Kurland, S. Joseph Mulé
Seven weeks passed without any positive specimens, and the therapist asked the patient if he would like to have a day off from the Clinic because of his good record. This offer was declined; Raymond preferred to come in every night. He had been feeling insecure and lethargic and did not know why he had these feelings. He also felt in a rut in regard to his work. He had been quite late getting to work several times. At first he was always on time, but now he seemed to be growing lax. He knew he had to travel quite a distance and had to leave early, but turned off the alarm and fell back to sleep. He said, “I can’t believe I’m this tired. I’ve been as late as two hours. What does it mean? Have I found my little niche? Is this bothering me? Am I trying to get fired?” The therapist suggested that it might be due to depression: “You have nothing to live for; no goal that gives your life meaning. Right now your life is without a future, there is a gloomy past, and not much present.”
Bacteria Causing Gastrointestinal Infections
Published in K. Balamurugan, U. Prithika, Pocket Guide to Bacterial Infections, 2019
B. Vinoth, M. Krishna Raja, B. Agieshkumar
Noninvasive modalities of diagnosing H. pylori include IgG antibody detection, antigen detection in stool sample, and urea breath test. Serology is not useful because it does not identify an active infection. The invasive method of diagnosing H. pylori is by performing an endoscopy and taking biopsies from the stomach, and by subjecting the biopsy specimen for rapid urease test (RUT), histopathological examination (HPE), culture and sensitivity, or PCR study. Classical endoscopic finding in patient with H. pylori infection is the presence of benign-appearing ulcers either in the stomach, usually along the lesser curve or in the first part of the duodenum (Figure 1.3). Duodenal ulcers are more common than gastric ulcers. Often special stains are used to demonstrate H. pylori on HPE (Figure 1.3). The common method of diagnosing H. pylori in clinical practice is by endoscopy and biopsy followed by rapid urease test and HPE.
Clinical feasibility of radiofrequency ablation using novel adjustable separable electrodes with a multipurpose needle for treating small hepatocellular carcinomas: a prospective single center study
Published in International Journal of Hyperthermia, 2023
Se Woo Kim, Jeong Min Lee, Jae Hyun Kim, Sae Jin Park, Jeong Hee Yoon, Ijin Joo
Immediately after RFA completion, liver dynamic CT was performed to assess ablation size, possible complications, and technical success based on the reporting criteria suggested by the International Working Group on Image-guided Tumor Ablation [28,29]. Technical success of RFA was defined as complete coverage of the target tumor with sufficient ablation zone (> 3 mm) on immediate follow-up CT [28,29]. Any nodular enhancement at the ablation margin was considered to be a residual unabated tumor (RUT), and patients with RUT underwent additional ablation on the same day [30]. The volume of the ablation zone was calculated using the longitudinal diameter along the electrode axis (Dl), the short diameter perpendicular to the electrode axis (Ds), and the vertical diameter (Dv) with the following formula:
Antioxidant and anti-inflammatory protective effects of rutin and kolaviron against busulfan-induced testicular injuries in rats
Published in Systems Biology in Reproductive Medicine, 2022
Sunny O. Abarikwu, Rex-Clovis C. Njoku, Ifeoma G. John, Benjamin A. Amadi, Chidimma J. Mgbudom-Okah, Chigozie L. Onuah
Animals treated with BUS showed an increased level of nitrite in the testes that decreased after co-treatment with rutin or kolaviron separately or in combination (Figure 2A). Busulfan treatment also caused an increase in testicular myeloperoxidase activity in rats which was significantly (p < 0.05) decreased on co-supplementation with rutin and kolaviron separately or in combination. The testis myeloperoxidase activity was much more decreased after separate co-treatment with rutin than kolaviron. However, the combined treatment regimen of RUT and KV was better than the effect observed after single administration of kolaviron (Figure 2B). Testicular TNF-α concentration was decreased in the BUS and BUS + RUT groups relative to the values seen in the control rats (p < 0.05). The concentration of TNF-α was increased in the testis of BUS + KV relative to the BUS treated animals and was recovered to the values seen in the control while the values of TNF-α in the BUS + KV + RUT animals was reduced compared to the BUS + KV group but toward the values seen in the BUS + RUT – treated animals (Figure 2C).
Beneficial effects of rutin in diabetes-induced deficits in acquisition learning, retention memory and pain perception in rats
Published in Nutritional Neuroscience, 2020
Parisa Hasanein, Abbasali Emamjomeh, Nasibeh Chenarani, Mussa Bohlooli
Rutin (3, 30, 40, 5, 7-pentahydroxyflavone-3-rhamnoglucoside) (RUT) also known as quercetin-3-rutinoside or vitamin P is found in fruits, vegetables and plant-derived beverages such as tea and wine. It is abundantly found and distributed in plants such as in buckwheat seed, fruits, and fruit rinds, especially citrus fruits (orange, grapefruit, and lemon). It has a long history of use in nutritional supplements for its action against oxidative stress, inflammation, and hyperglycemia, the key players involved in the progression of diabetes.15–17 The antioxidant effect of RUT in diabetes was exhibited by its ability to scavenge free radicals and to inhibit lipid peroxidation in STZ-induced diabetic animals.18 In addition, RUT has anti-inflammatory activity, which is evidenced by its ability to inhibit proinflammatory cytokines and suppress microglial activation, which would otherwise lead to neuroinflammation.19