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Musculoskeletal
Published in Vincent Helyar, Aidan Shaw, The Final FRCR, 2017
These are found in up to 40% of children aged <2 years; 95% are seen in those aged under 20 years of age. After 30 years of age, they are rare. They are benign, asymptomatic and regress spontaneously. Lesions >2 cm are known as non-ossifying fibroma. Most affect a single bone, 25% are polyostotic (associated with neurofibromatosis, fibrous dysplasia or Jaffe–Campanacci syndrome).
Test Paper 6
Published in Teck Yew Chin, Susan Cheng Shelmerdine, Akash Ganguly, Chinedum Anosike, Get Through, 2017
Teck Yew Chin, Susan Cheng Shelmerdine, Akash Ganguly, Chinedum Anosike
Benign bone tumours in the fibrous group include benign fibrous cortical defect (FCD), non-ossifying fibroma (NOF), osteo-fibrous dysplasia (OFD), fibrous dysplasia (FD) and fibroma. Benign fibrous cortical defects and non-ossifying fibromas are the most common tumours in the benign fibrous group. Benign cortical defects and non-ossifying fibromas are eccentric, cortical bone lesions, usually located in the metaphyses of long bones. Non-ossifying fibromas are usually larger than fibrous cortical defects. The most common locations for fibrous cortical defects are the distal femur, proximal tibia and distal tibia. They occur less commonly in the fibula and are relatively uncommon in the upper extremity.
Tumor-induced osteomalacia caused by a massive phosphaturic mesenchymal tumor of the acetabulum: A case report
Published in Modern Rheumatology, 2018
Kimitaka Nakamura, Masanobu Ohishi, Tomoya Matsunobu, Yasuharu Nakashima, Akio Sakamoto, Akira Maekawa, Yoshinao Oda, Yukihide Iwamoto
Tumors that are responsible for TIO include PMT, GCT, fibrous dysplasia, osteosarcoma, and so on [8–10]. Based on histopathology, Weidner et al. subdivided PMTs into four categories: (i) phosphaturic mesenchymal tumor mixed connective tissue (PMTMCT) variant, (ii) osteoblastoma-like variant, (iii) non-ossifying fibroma-like variant, and (iv) ossifying fibroma-like variant [8]. The majority of FGF-23-producing tumors responsible for TIO are considered to be of the PMTMCT variant [11]. Jiang et al. reported that 46% of the tumors responsible for TIO were PMTMCT [10].