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Ear Trauma
Published in R James A England, Eamon Shamil, Rajeev Mathew, Manohar Bance, Pavol Surda, Jemy Jose, Omar Hilmi, Adam J Donne, Scott-Brown's Essential Otorhinolaryngology, 2022
A high-definition temporal bone scan should be performed. Where hearing loss or vertigo are evident, but with no fracture on CT, T1-weighted magnetic resonance imaging (MRI) may demonstrate a hyperintense signal in the labyrinth indicative of haemorrhage, and it may also identify temporal lobe contusion. Gadolinium-enhanced MRI of the facial nerve, or angiography to exclude vascular injury, more accurately assesses the degree of damage to these structures.
Radionuclide Bone Scintigraphy
Published in Michael Ljungberg, Handbook of Nuclear Medicine and Molecular Imaging for Physicists, 2022
Kanhaiyalal Agrawal, Gopinath Gnanasegaran
In Paget’s disease, abnormal bone remodelling is seen. A bone scan is useful for confirming the diagnosis, and assessing the disease extent. However, most often, it is seen incidentally on a bone scan performed due to other causes. The typical scintigraphic pattern is intense florid tracer uptake in the involved bones with a blooming uptake appearance (Figure 11.16).
Paper 1
Published in Amanda Rabone, Benedict Thomson, Nicky Dineen, Vincent Helyar, Aidan Shaw, The Final FRCR, 2020
Amanda Rabone, Benedict Thomson, Nicky Dineen, Vincent Helyar, Aidan Shaw
Bone scans are sensitive but not specific for osteomyelitis. The bone scan will often be abnormal before any radiographic changes are evident. The three phases are angiographic, tissue and osseous phases. Osteomyelitis will demonstrate increased tracer uptake on all three phases due to increased blood flow to the region, increased tracer uptake within the adjacent inflamed soft tissues and then increased uptake within the bone itself. This is in contrast to cellulitis where uptake would only be increased on the angiographic and tissue phases.
Piflufolastat F-18 (18F-DCFPyL) for PSMA PET imaging in prostate cancer
Published in Expert Review of Anticancer Therapy, 2022
Andrew F. Voter, Rudolf A. Werner, Kenneth J. Pienta, Michael A. Gorin, Martin G. Pomper, Lilja B. Solnes, Steven P. Rowe
Because progression of local disease or metastases to lymph node or soft-tissues cannot be detected by bone scans, evaluation for soft tissue disease is performed by CT or MRI [3]. MRI excels at evaluation of the prostate bed, but is typically impractical for unguided screening studies, although there have been efforts to use whole-body MRI for staging [10]. CT scans can rapidly evaluate the entire body, but are less sensitive [6]. Technological advances have continued to improve the accuracy of cross-sectional imaging and recent evidence suggests that multiparametric MRI (mpMRI) has improved sensitivity for the detection of prostate cancer, although it is limited to detection of disease within the pelvis [11,12]. As with bone scans, cross-sectional imaging does not detect the malignancy per se, but rather the distortive effects of uncontrolled proliferation, which is only observable later in the disease course.
Cancer rehabilitation: current trends and practices within an Austrian University Hospital Center*
Published in Disability and Rehabilitation, 2020
Richard Crevenna, Franz Kainberger, Christoph Wiltschke, Christine Marosi, Michael Wolzt, Fadime Cenik, Mohammad Keilani
In the last two decades, exercise has been shown to be an effective method in cancer treatment and rehabilitation [10–26]. Researchers of the Department of Physical Medicine, Rehabilitation and Occupational Medicine of the Medical University of Vienna as a part of the CCC Vienna were able to implement the first Austrian Exercise Group of Breast Cancer Patients during adjuvant chemotherapy, and to publish the worldwide first application of exercise in metastatic bone disease (endurance capacity = 150%), and the worldwide first application Neuromuscular Electrical Stimulation (NMES) in patients suffering from metastatic bone and brain disease (please see Table 2). Such interventions enable the patients to gain self-confidence and independence from others help, by increasing endurance capacity and muscle strength (and muscle mass respectively), quality of life and participation [9,16–22]. Medical history, clinical examination, different laboratory parameters, electrocardiography, echocardiograph findings, exercise testing, spirometry, radiographic findings, and bone scans are needed for planning and receipting such individual exercise programs [16].
Diagnostic value of 18-F fluorodeoxyglucose PET/CT and bone scan in Schnitzler syndrome
Published in Autoimmunity, 2019
L. Alix, A. Néel, B. Cador, A. Smail, J. Serratrice, F. Closs-Prophette, P. Jego, A. Devillers, O. Decaux
In contrast to PET/CT, there seemed to be a correlation between SchS disease activity and bone scan activity. Thus, bone scans may be the best radiological examination in SchS, both for diagnosis and to monitor disease activity, as all patients had significant disease activity scores (ranging from 6 to 15) and increased radiotracer uptake in the long bones. Although systematic bone scan might not be recommended since the diagnosis and follow-up of SchS is mainly clinical and biological, objective findings of abnormal bone remodelling is a minor criterion of the Strasbourg criteria and therefore bone imaging should be carried out to confirm diagnosis. Bone scan may also help during the follow-up to distinguish disease relapse from other aetiologies of bone, joint, or muscle pain, such as vertebral fracture, tendinopathy, or fibromyalgia. MRI may also be useful for the diagnosis and follow-up of SchS, although less specific than bone scans.