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Diabetes Mellitus, Obesity, Lipoprotein Disorders and other Metabolic Diseases
Published in John S. Axford, Chris A. O'Callaghan, Medicine for Finals and Beyond, 2023
Treat infection promptly and drain pus. Inspect footwear and change it if inappropriate. Surgical intervention can be used to improve the proximal blood supply if appropriate. Note: Peripheral vascular disease in diabetes is often ‘distal’ in smaller vessels and less amenable to bypass surgery or angioplasty.
Infections
Published in Charles Theisler, Adjuvant Medical Care, 2023
An infection is the invasion of body tissues by a pathogenic agent (e.g., virus, fungus, parasite, or foreign bacterium). Infections can be localized or can spread through the blood and lymph to become systemic. They can be asymptomatic, or subclinical, or may have overt signs and symptoms. General local symptoms can be pus, redness, heat, soreness or swelling, foul odor, and fever. Systemic symptoms include fatigue, fever, aches, chills sweats, sore throat, nasal congestion, shortness of breath, stiff neck, urinary discomfort, diarrhea, or vomiting.
Fistula in ano
Published in Dinesh Kumar Jain, Homeopathy, 2022
Generalization should not have been made by Kent and Hahnemann from a single or a few observations. External outlets are must where pus is collected. Pus should be removed. If pus is not removed, then it is very difficult to get cured. In fistula in ano, “The fistula continues to discharge and because of constant reinfection from the anal canal or rectum, seldom if ever close permanently without surgical aid” (Rains & Ritchie, 1977, p. 1078). Fistula in ano has varied etiology like tuberculosis, ulcerative proctocolitis, Crohn's disease, bilharziasis, and lymphogranuloma inguinale. This varied etiology and continuous contamination and accumulation of pus require the evacuation of pus and treatment of a specific cause. Today we know, “About 2-3% of fistula in patients are tuberculous. The fistula will usually respond to antitubercular drugs” (Rains & Ritchie, 1977, p. 1080).
Offerings of carnal scriptures
Published in Journal of Lesbian Studies, 2023
The next day fresh wounds get sticky with pus; any movement reminds me of the soreness, breathing alone can cause it to sting. Maybe I’m really a submissive? Submissive, it’s an exercise in letting go. I’m not gonna try to control my life. I have to let it go, like I once did. I’d get on my knees, close my eyes believing in the feeling, the safety I felt in those prayers those fears laid down to rest in between those scriptures, pages the color of pus and thin like tissue, ruptured when my tears plopped down on them. That type of faith seems so long ago and the memories turned bible page thin. I didn’t want to stop believing that things would change, that:I would not lust after otras como yo Would not be broken down by rejectionNot be so fucken hornyNot be afraid to failI stop trying to control my lifeI be honest with myself.
Lacrimal Drainage Infections with Sphingomonas paucimobilis: Clinical Presentations, Complications and Outcomes
Published in Current Eye Research, 2023
Prerna Sinha, Sanchita Mitra, Nandini Bothra, Mohammad Javed Ali
The pus/discharge obtained was sent for routine microbiology diagnostics. For routine microbiology, the discharge was processed as follows: direct smears were stained with calcofluor white and 10% potassium hydroxide stains for fluorescence microscopy and Gram stain for bright-field microscopy. The rest of the discharge was inoculated onto solid media like blood and chocolate agars, Sabouraud’s dextrose agar (SDA), potato dextrose agars (PDA) and liquid media like thioglycollate broth, brain heart infusion media, and Robertson’s cooked meat media. All media were incubated aerobically at 37°C overnight, except for the SDA and PDA, which were incubated at 27°C in biological oxygen demand incubator and examined daily for any significant pathogen growth. An inoculated blood agar plate was also put for anaerobic incubation in GenbagR and examined for any significant growth after seven days of incubation at 37°C. Such significant growth was further processed for identification by standard biochemical reactions and an automated VITEK 2R compact system and polymerase chain reaction (Figure 1). Antibiotic susceptibility of these isolates was performed by the Kirby–Bauer disc diffusion method and reported as susceptible or resistant to tested antibiotics by matching with standard values.
Stem cell and tissue engineering approaches in pressure ulcer treatment
Published in The Journal of Spinal Cord Medicine, 2023
Silvia Perez-Lopez, Marcos Perez-Basterrechea, Jose Maria Garcia-Gala, Eva Martinez-Revuelta, Angeles Fernandez-Rodriguez, Maria Alvarez-Viejo
Pressure ulcers are today still a major healthcare problem, especially for those patients with limited mobility and/or sensation such as SCI patients. Treatments are usually based on PU stage and patient characteristics, and span from simple skin wound care in mild cases to surgery in the more severe PU. Advanced therapy medicinal products are innovative complex biological products that are being examined in preclinical studies, and many are also being translated to the clinical setting as alternative therapeutic tools for several diseases. Among these diseases, PUs will especially benefit from these scientific advances, as for the more severe or complex injuries, standard of care treatment is not always successful. Taking in mind the characteristics of PUs, especially those with larger dimensions, where cell treatment may not be possible, tissue engineering approaches arise as the most promising option. Although several scaffolds, combined or not with cells, have been assayed, both in pre-clinical and clinical studies, its use in daily clinical practice have not been achieved. In this sense, further research is needed, with special attention to the development of new natural scaffolds, some of which could be obtained autologously, avoiding some safety and biocompatibility concerns.