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Conjugated Graphene Gold Nanocomposites for Cancer Therapy
Published in Devarajan Thangadurai, Saher Islam, Charles Oluwaseun Adetunji, Viral and Antiviral Nanomaterials, 2022
Zaira Zaman Chowdhury, Abu Nasser Faisal, Shahjalal Mohammad Shibly, Devarajan Thangadurai, Saher Islam, Jeyabalan Sangeetha
Sonication and photo-aided deposition, like MWT, promote fast heating of the mixture, but the mechanism is markedly dissimilar for both circumstances. Ultrasonic reduction, as well as the photo-irradiated reduction, are both environmentally friendly, one-pot fabrication approach for the synthesis of rGO–AuNPs composites (Bai and Shen 2012). However, the autoclave atmosphere dictates whether the procedure is hydrothermal or solvothermal. Au nano-crystals, having size ranges from 10 to 20 nm, were decorated over GO without the application of any reductants or capping agents using hydrothermal approach (Qin et al. 2012). Electrochemical deposition is facilitated by the application of a voltage differential. This straightforward, environmentally friendly, cost-effective, and quick technique aims to produce dense, homogenous nanocomposites using only the precursors (Pham et al. 2011; Bai and Shen 2012).
Naturopathy
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
Bhushan R. Rane, Sandip A. Tadavi, Raj K. Keserwani
Hydrotherapy is a branch of nature cure. It is treatment of disorder using different types of water applications. The different types of water applications are in practice since ancient times. Hydrothermal therapy uses the effect of temperature, as in hot and cold baths, saunas, wraps, etc., and all its forms, such as solid, liquid, vapor, ice, and steam, either internally or externally. Water is, without doubt, the most ancient of all remedial agent for disease. This great healing property has now been systematized and made into a special type of science. Hydrotherapeutic applications are generally used in different forms of temperature. The temperature forms of the applications are given in Table 12.2.
Dams and dambusters
Published in Théodore H MacDonald, David Player, Mathura P Shrestha, Sacrificing the WHO to the Highest Bidder, 2018
Because the Aral Sea is situated in the Central Asian deserts, and at an altitude of only 53 metres above sea level, it functions as a gigantic evaporator. Approximately 60 km3 of water evaporate annually. In this way the ‘sea’ contributed to hydrothermal regime improvement, modifying the water supply to desert flora, creation of pastureland and creation of artesian wells. Up until at least 1960, this all served to maintain a stable ecological balance.
Processing Effect on L-DOPA, In Vitro Protein and Starch Digestibility, Proximate Composition, and Biological Activities of Promising Legume: Mucuna macrocarpa
Published in Journal of the American College of Nutrition, 2019
Chetan Aware, Ravishankar Patil, Govind Vyavahare, Ranjit Gurav, Vishwas Bapat, Jyoti Jadhav
RP-HPLC quantification of L-DOPA content in raw and processed MM seeds is shown in Figure 1. The L-DOPA content of raw seeds was higher (115 ± 3.25 mg g−1), and was reduced in the processing of seeds. The greater reduction of L-DOPA level in autoclaving (58.6 ± 2.92 mg g−1) and boiling (52.4 ± 2.10mg g−1) treatment was noticed when compared to the control. Processing techniques such as soaking (76.8 ± 3.13 mg g−1) in water and roasting (88.8 ± 1.96 mg g−1) have the minimum effect on L-DOPA level. The L-DOPA content in a combination of soaking plus boiling and soaking plus roasting was 72.4 ± 2.59 mg g−1 and 69.4 ± 2.17 mg g−1, respectively. Significant loss in the L-DOPA content was observed in hydrothermal treatments. This may be due to leaching of L-DOPA from the seeds (9). Though L-DOPA is being used as anti-Parkinson’s drug, it has several antinutritional effects, including nausea, vomiting, and other disorders. Hence, for the consumption of MM seeds as a staple food, it is necessary to reduce the L-DOPA level from the beans. In this connection, hydrothermal processes can be a good treatment.
Facile development, characterization, and evaluation of novel bicalutamide loaded pH-sensitive mesoporous silica nanoparticles for enhanced prostate cancer therapy
Published in Drug Development and Industrial Pharmacy, 2019
Seema Saroj, Sadhana J. Rajput
Typically, MCM-41 MSNs containing CTAB were prepared based on template-based synthesis method as per literature reported method [34] with minor moderation. Briefly, 2.21 grams (g). CTAB was added to 16 milliliters (mL) of de-ionized water with continuous stirring for 5–10 minutes (min). Totally, 3.26 ml of TMAOH was subsequently added dropwise to the above mixture under vigorous stirring. After 10 min, 3 g fumed silica was added to the reaction mixture and stirred continuously for 2 h. This was followed by hydrothermal treatment for 48 h. Subsequently, the thick white slurry obtained was filtered and washed with de-ionized water completely. This was further dried overnight to obtain a dry powder. Surfactant template was evacuated by subjecting to calcination for 5 h at 823K.
Tailor-made pH-sensitive polyacrylic acid functionalized mesoporous silica nanoparticles for efficient and controlled delivery of anti-cancer drug Etoposide
Published in Drug Development and Industrial Pharmacy, 2018
Seema Saroj, Sadhana J. Rajput
MCM-41 was synthesized hydrothermally as per the literature reported method via template synthesis mechanism with slight modifications [28]. Accurately weighed, 4.42 grams (g) CTAB was added to 33 milliliters (mL) of de-ionized water and stirred for 5 minutes (min). To this, 6.52 ml of TMAOH was added dropwise to the reaction mixture under continuous stirring. After elapsing of 10 min, 6 g of fumed silica was added. Reaction mixture was kept under continuous stirring for 2 h. Subsequently, hydrothermal treatment was given for 48 h. The thick white slurry was filtered, washed with de-ionized water thoroughly and dried. Consequently, the structure template CTAB was completely detached by calcination at 823 K for 5 h. The fine product MCM-41 was obtained and further confirmed by characterization using infrared spectroscopy (IR) and low angle X-Ray diffraction studies (LXD).