China 
Africa 
Explore chapters and articles related to this topic
Lactic Acid Bacteria Application to Decrease Food Allergies
Published in Marcela Albuquerque Cavalcanti de Albuquerque, Alejandra de Moreno de LeBlanc, Jean Guy LeBlanc, Raquel Bedani, Lactic Acid Bacteria, 2020
Vanessa Biscola, Marcela Albuquerque Cavalcanti de Albuquerque, Tatiana Pacheco Nunes, Antonio Diogo Silva Vieira, Bernadette Dora Gombossy de Melo Franco
Regarding the potential application of LAB to reduce wheat allergy, in vitro studies carried out in cell model, demonstrated that probiotic Bifidobacterium lactiswas able to inhibit the toxic effects caused by the ingestion of wheat gliadin. Some authors found that Lactobacillus rhamnosus GG may contribute to improving gut permeability, presenting potential to prevent the disruption of the gut epithelial barrier caused by this protein. Other results also suggested that the administration of probiotics, such as Bifidobacterium animalis subsp. lactis BB-12, Lactobacillus acidophilus, and Lactobacillus rhamnosus GG could suppress the production of specific IgE (Lindfors et al. 2008, Orlando et al. 2014, Paparo et al. 2019b). Still on this matter, De Angelis et al. 2007 observed that commercial probiotic VSL#3, used as starter for dough fermentation, was able to provoke extensive hydrolysis of wheat proteins, cleaving some IgE-binding antigens. Besides, the authors reported that the remaining IgE-binding proteins were completely hydrolyzed by pepsin and pancreatin after simulated digestion.
Dairy Product Consumption, Dairy Fat, and Cardiometabolic Health*
Published in Nathalie Bergeron, Patty W. Siri-Tarino, George A. Bray, Ronald M. Krauss, Nutrition and Cardiometabolic Health, 2017
Benoît Lamarche, Nathalie Bergeron, Patty W. Siri-Tarino, George A. Bray, Ronald M. Krauss
Finally, the impact of consuming fermented dairy products on plasma lipid levels has been of interest for more than 30 years. Agerholm-Larsen et al. (2000a) published a meta-analysis of six RCTs on Gaio®, a commercially available yogurt fermented with one strain of Enterococcus faecium and two strains of Streptococcus thermophiles. Data indicated that consumption of the fermented yogurt significantly reduced plasma LDL-C compared with consumption of control yogurts, which were of identical composition to the test yogurt, but chemically fermented with an organic acid instead of a live bacterial culture. Such data have been reproduced in some (Anderson and Gilliland 1999; Andrade and Borges 2009) but not all (de Roos et al. 1999; Sadrzadeh-Yeganeh et al. 2010) of the more recent studies of fermented dairy intake. Finally, consumption of fermented dairy of any form seems to have very little impact on plasma TG (Schaafsma et al. 1998; Bertolami et al. 1999; St-Onge et al. 2002; Hansel et al. 2007), while the effects on HDL-C concentrations have not been investigated thoroughly. In a small parallel RTC, we have shown that 4-week consumption of yogurt products containing different doses of Bifidobacterium animalis subsp. lactis (BB-12) and Lactobacillus acidophilus (LA-5) had no significant impact on plasma LDL-C, TG, and HDL-C concentrations compared with a control yogurt (Savard et al. 2011). This is an area that certainly deserves intensified research.
Probiotics
Published in Linda M. Castell, Samantha J. Stear (Nottingham), Louise M. Burke, Nutritional Supplements in Sport, Exercise and Health, 2015
In a study on the effect of a L. casei supplement on URTI, immunological and hormonal changes in soldiers participating in three weeks of commando training followed by a five-day combat course, no difference in infection incidence between groups receiving daily probiotic or placebo was reported (Tiollier et al., 2007). The major finding was a significant decrease in salivary immunoglobulin A (IgA) concentration after the combat course in the placebo group, with no change over time in the probiotic group. A randomized, placebo-controlled trial in 64 university athletes reported a lower incidence of URTI episodes during a four-month winter training period in subjects receiving daily L. casei Shirota compared with placebo, and this study also reported better maintenance of salivary IgA in the probiotic group (Gleeson et al., 2011). Importantly, in both athlete and non-athlete populations, falls in salivary IgA have been associated with increased URTI incidence (Walsh et al., 2011b). Another study using L. fermentum reported reduced URTI incidence among male but not female athletes during 11 weeks of training (West et al., 2011b). A recent large scale, randomized, placebo-controlled trial involving 465 physically active men and women reported fewer URTI episodes (relative risk ratio 0.73) in those who ingested daily a Bifidobacterium animalis subspecies lactis Bl-04 compared with placebo over a 150-day intervention period (West et al., 2014). Although most studies to date have examined probiotic effects in recreationally active individuals or endurance athletes, a recent study on elite rugby players provides evidence that beneficial effects of probiotics in reducing URTI incidence, but not severity, may extend to team games players (Haywood et al., 2014).
The double-edged sword of probiotic supplementation on gut microbiota structure in Helicobacter pylori management
Published in Gut Microbes, 2022
Ali Nabavi-Rad, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Abbas Yadegar, Sinéad Marian Smith, Mohammad Reza Zali
B. infantis 35624 and B. breve YIT10347 activate the intestinal DCs by interacting with TLRs and stimulating RA metabolism. As a result, DCs activation elevates the expression of IL-10 and the number of Foxp3+ Treg and type 1 regulatory T (Tr1) cells. Moreover, L. rhamnosus GG and L. acidophilus can reduce the number of Th17 cells and the expression of IL-23 and IL-17 cytokines through prevention of STAT3 and NF-κB signaling and further shift the balance between pro-inflammatory M1 and immunosuppressive M2 macrophage toward M2 phenotype.178 In contrast, Bifidobacterium animalis spp. lactis Bl 5764 is able to promote IL-17A expression by CD4+ T lymphocytes in vitro. L. reuteri Lr 5454 co-culture with DCs can promote Tregs, and regenerating islet-derived protein 3-beta (Reg3b) expression in a NOD2-dependent manner and further induce IL-22 production.179 IL-22 plays an imperative role in preserving gut homeostasis and tissue regeneration. Furthermore, this cytokine accelerates the colonization of Phascolarctobacterium bacterium and thereby prevents C. difficile infection (CDI).180
Improved gut microbiome recovery following drug therapy is linked to abundance and replication of probiotic strains
Published in Gut Microbes, 2022
Jamie FitzGerald, Shriram Patel, Julia Eckenberger, Eric Guillemard, Patrick Veiga, Florent Schäfer, Jens Walter, Marcus J Claesson, Muriel Derrien
Strategies to promote gut microbiota structural and functional recovery following exposure to antibiotics include defined approaches such as pre- and probiotics.5–7 Although probiotics show species-specific benefits on AAD,8 the reported effects on gut microbiota recovery have been inconsistent between studies, which differ substantially in design, population, and the probiotic strains and antibiotics used. Two recent studies in healthy subjects showed contradictory findings in that post-antibiotic gut microbiome recovery is either improved by a fermented milk product containing Bifidobacterium animalis subsp lactis BB-129 or substantially impaired by a multi-strain product.10 These contradictions emphasize the limitations in our ecological understanding of the impact of probiotics, and the effects of specific strains, on microbiome recovery.
Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum
Published in Gut Microbes, 2021
Weilin Liao, Imran Khan, Guoxin Huang, Shengshuang Chen, Liang Liu, Wai Kit Leong, Xiao Ang Li, Jianlin Wu, W. L. Wendy Hsiao
Early researches on prebiotics were mainly focusing on plant foods that contain inulin, polyphenols, fructo- or galactooligosaccharides. More recently, certain functional foods, such as Geranium dielsianum tea, cassava bagasse flour, and kiwifruit pectins, have also been reported for their prebiotic effects.23–25Gynostemma pentaphyllum is a dietary herbal medicine known for its many health benefits. In our previous studies, we demonstrated that triterpenoid saponins from Gynostemma pentaphylum together with ginseng, rotoginseng display prebiotic-like effects in the normal mouse model.26 Further research showed that G. pentaphylum saponin (GpS) exerts significant cancer-preventive effects in ApcMin/+ mice through modulating the GM composition and the gut epithelial microenvironment.27–29 We hypothesize that treatment with GpS might have preserved a particular group(s) of bacteria that provides health advantage to the host. In this current study, we performed both in vivo and in vitro experiments to track down the potential bacterial group(s) that confers the prebiotic and cancer-preventive effect of GpS. We provide evidence that Bifidobacterium animalis might be the critical gut microbe contributing to the anticancer and cancer-preventive activities of GpS against colonic cancer.