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Selenium Sulfide
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Selenium sulfide is an antifungal agent highly active in inhibiting the growth of Malassezia species (formerly known as Pityrosporum), micro-organisms which play an important role in the development of dandruff. It is also a proven cytostatic agent, slowing the growth of both hyperproliferative and normal cells. Topical selenium sulfide has been used for decades in the treatment of dandruff, seborrheic dermatitis and tinea versicolor. Selenium sulfide is available in various topical formulations including shampoo, lotion, cream, foam, and suspension.
Superficial mycoses in the elderly
Published in Robert A. Norman, Geriatric Dermatology, 2020
B. P. Glick, M. Zaiac, G. Rebell, N. Zaias
The management of tinea versicolor includes a number of topical and systemic agents that are effective in controlling the disease in the aged. The most common is 2.5% selenium sulfide lotion, which is applied within and around the affected area, left in place for approximately 10–20 minutes and then washed off thoroughly. The process is repeated daily for 2 weeks until clearing, then one to two times per month prophylactically21. Numerous dosing schedules for selenium sulfide have been used, each with similar efficacy.
Treatment of skin with antioxidants
Published in Roger L. McMullen, Antioxidants and the Skin, 2018
Typically, selenium is available for topical delivery in the form of selenium sulfide (SeS2 or Se2S6) and L-selenomethionine.12 In personal care products, selenium sulfide is mostly used in shampoos to treat seborrheic dermatitis or dandruff.80,81 While selenium sulfide does not penetrate skin, topical administration of L-selenomethionine leads to effective incorporation into the skin’s structure.82
Novel therapeutics for dry eye disease
Published in Annals of Medicine, 2023
Duoduo Wu, Louis Tong, Arun Prasath, Blanche Xiao Hong Lim, Dawn Ka-Ann Lim, Chris Hong Long Lim
Other therapeutic options available in other centres but not mentioned in the article include topical rebamipide (Mucosta UD), topical perfluorohexyloctane, topical azithromycin, systemic pilocarpine, oral gamma-linolenic acid, amniotic membrane related treatment options; such as Prokera and amniotic membrane extract, topically administered mesenchymal stem cell-derived exosomes and scleral lenses such as PROSE® or EyePrintPRO™. Additional non-pharmacological devices targeting meibomian gland dysfunction not mentioned include TearCare®, iLux®, Mibo Thermoflo®. Promising therapeutics on the horizon include selenium sulfide containing ointments.