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Seborrhea/Seborrheic Dermatitis/Dandruff
Published in Charles Theisler, Adjuvant Medical Care, 2023
Shampoos: Standard medical treatment involves the frequent use of dandruff shampoos containing selenium sulfide (Selsun Blue) or zinc pyrithione (Head & Shoulders, Zincon, Dandrex) or ketoconazole (Nizoral A-D) and topical steroids if necessary.3,4 Apply the shampoo to the scalp at the first part of the bathing/showering routine and then wait until the end to rinse it off. This technique maximizes the shampoo's contact time on the skin. For severe disease, keratolytics such as salicylic acid (Neutrogena T/ Sal) or coal tar (Neutrogena T/Gel, DHS Tar) preparations may be used to suppress and remove dense scale.4
Role of Environmental Toxicants and Inflammation in Parkinson’s Disease
Published in Abhai Kumar, Debasis Bagchi, Antioxidants and Functional Foods for Neurodegenerative Disorders, 2021
Biddut Deb Nath, Dipti Debnath, Rokeya Pervin, Md. Akil Hossain
Sweating and Skin Problems: Owing to the inadequate activity of the autonomic nervous system, PD patients have trouble regulating body temperature, which often induces unnecessary sweating. PD patients’ face becomes quite oily, especially on the forehead and on the nose edges. The scalp seems to become extremely oily, leading to dandruff, and in certain contexts, the skin becomes harsh, wrinkled, and very dry.57
Commentary
Published in Yvette Hunt, The Medicina Plinii, 2019
While some of the terminology is similar to that used at Medicina Plinii 3.27, the conditions treated are different. In addition to louse-associated conditions, this chapter addressed dandruff without naming it, incorporating it within “itch”.
Effect of oral administration of Triphala, a polyphenol-rich prebiotic, on scalp sebum in patients with scalp seborrhea a randomized clinical trial
Published in Journal of Dermatological Treatment, 2022
Elham Zareie, Parvin Mansouri, Hamed Hosseini, Omid Sadeghpour, Laila Shirbeigi, Someyeh Hejazi, Majid Emtiazy
The current randomized controlled double-blind, placebo-controlled study showed that Triphala, an herbal polyphenol-rich prebiotic, is effective in reducing scalp seborrhea in 14–50 years old patients with scalp seborrhea in a period of 8 weeks. Participants in the Triphala group showed a 25% improvement in their scalp sebum score, while participants in the placebo group experienced a 24% deterioration. This finding is consistent with prior studies demonstrated various clinical benefits on the skin after oral supplementations containing probiotics and/or prebiotics. Reygagne et al. conducted a placebo controlled trial in patients with moderate to severe dandruff. They noted in the probiotic Lactobacillus paracasei strain ST11 group the free and adherent dandruff improved significantly. The scalp seborrhea score had reduced by 46% and the scalp microbiota was restored with ST11 after 8 weeks. As they discussed this probiotic have positive impacts on the skin barrier. It would modulate the skin immune system as well as rebalancing the scalp microbiota (12).
Efficacious and safe management of thick scales, redness and flaky scalp condition using a specific shampoo containing urea, glycolic acid, salicylic acid, icthyol pale and laureth 9
Published in Cogent Medicine, 2018
Bianca Maria Piraccini, Nicolò Brandi, Aurora Alessandrini, Francesca Bruni, Michela Starace
Dandruff is a common condition which is characterized by accumulation of scales, oily, red and flaky scalp, often accompanied by itch. The aim of our study was to evaluate the cleansing efficacy and tolerability of a new shampoo (Psorisdin Shampoo®) containing urea, glycolic acid, salicylic acid, ichthyol pale and laureth 9 compared to a nonspecific shampoo. The use of Psorisdin Shampoo® resulted in an important improvement of patient’s scalp and hair clinical appearance and was well tolerated, showing higher cleansing and soothing property than a nonspecific shampoo; moreover, its effect was maintained over time, even after 5 days since the last wash.
Comparative antidandruff efficacy of plant extracts prepared from conventional and supercritical fluid extraction method and chemical profiling using GCMS
Published in Journal of Dermatological Treatment, 2022
Ratish Chandra Mishra, Rosy Kumari, Jaya Parkash Yadav
Dandruff is a prevalent chronic inflammatory scalp condition with itching and erythematic skin, affecting about half of the population around the world (1). Dandruff causes socio-psychological impact; as the flaky scalp may look unhygienic and can distress the individual’s self-esteem (2). Multiple triggers for dandruff include microbial growth, disruption of the skin barriers, epidermal cellular proliferation, differentiation, oxidative stress, cytokines, and sebum production (3–6). Propionibacterium, Staphylococcus, and Malassezia are the most abundant microbial genera found on the scalp surface (7,8). Anti-dandruff agents such as zinc pyrithione, ciclopirox, selenium sulfide, minoxidil, coal tar, ketoconazole are commonly used although these compounds have disadvantages such as scalp dryness, discoloration of hairs, toxicity to eyes, irritation, headache, etc. (9–12). Research on the therapeutic potential of natural products will provide an enthralling alternative. In India, a variety of plants in Ayurveda are known for their anti-dandruff properties including amla, reetha, shikakai, fenugreek, lemon, licorice, neem, heena, etc. In addition, they also provide hair conditioning and growth (13–15). Phytochemical extraction methods such as cold percolation, soxhlet, maceration, etc., use large amounts of toxic solvents (16). In 1997 the Kyoto Protocol also emphasized limiting the production and use of these organic solvents as they damage the ozone layer (17). Conversely, SFE is safe to use and supercritical fluids have combined properties of liquids and gases above their critical temperature and pressure point (18). SFE- CO2 provides a non-polar environment however its polarity can be modified by the use of co-solvents such as ethanol, isopropyl alcohol, ammonium formate in methanol to extract relatively polar compounds (19,20). After extraction, for the identification of phytochemicals GC-MS is widely used (21,22). Various compounds have already been extracted using SFE from the plants selected in this study such as palmitic acid and borneol from P. granatum (23), cinnamaldehyde from C. zeylanicum (24), saponins from G. glabra (25), essential oil from S. aromaticum (26), A. indica (27), aloe emodin and barbaloin from Aloe vera (28), eugenol from S. aromaticum (29). Although their antidandruff efficacy has not been reported therefore, the study was proceeded to screen their antimicrobial potential against dandruff associated pathogens.