China
Africa
Explore chapters and articles related to this topic
Biotransformation of Monoterpenoids by Microorganisms, Insects, and Mammals
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
Yoshiaki Noma, Yoshinori Asakawa
Concentrated cell suspension of Pseudomonas sp. strain (PL) was inoculated to the medium containing 1-p-menthene (62) as the sole carbon source. It was degraded to give β-isopropyl pimelic acid (248) and methylisopropyl ketone (251) (Hungund et al., 1970) (Figure 22.48).
Bacterial Peptides and Cytokines as Sleep Substances
Published in Alan J. Husband, Psychoimmunology CNS-Immune Interactions, 2019
R. Brown, K.E. King, M.J. Crowe, T.K. Roberts
In the present paper we present findings which add support to the notion that sleep and immunity are functionally related. Firstly we discuss the effects of a novel muramyl peptide, N-acetylmuramyl-L-ala-τ-D-glu-meso-2,6-diamino[3,4,5-3H] pimelic acid (NAMP) on EEG activity and fever production. Secondly, we present preliminary findings which describe the uptake of labelled interleukin-1 in vivo in the anaesthetised rat brain.
Targeted and Untargeted Metabolomics for Specific Food Intake Assessment
Published in Dale A. Schoeller, Margriet S. Westerterp-Plantenga, Advances in the Assessment of Dietary Intake, 2017
Carl Brunius, Huaxing Wu, Rikard Landberg
In the original investigation of whole grain rye biomarkers, the 20 highest ranked metabolite features were chosen for identification. These could be divided into five distinct categories (Hanhineva et al. 2015): (1) Low-abundant metabolites, where annotation and identification was not possible; (2) metabolites/derivatives of phenolic compounds normally found in the rye bran, related to DHPPA (Ross et al. 2004; Marklund et al. 2013a) and caffeic acid sulfate; (3) phenylacetamides possibly related to benzoxazinoid metabolism (Zikmundova et al. 2002; Beckmann et al. 2013; Hanhineva et al. 2014); (4) dicarboxylic acids (i.e., pimelic acid) (Bondia-Pons et al. 2013; Pekkinen et al. 2014); and (5) carnitines of unknown structure. Whereas a majority of the annotated compounds have been either previously suggested as potential biomarkers of rye or belonging to such a class, the presence of carnitines represented a novel and highly interesting finding in relation to whole grain rye exposure. Carnitines have previously been linked to, for example, metabolism of betaine (Pekkinen et al. 2013, 2015) and are frequently associated with cardiometabolic disturbances (Brunius et al. 2015). This implies that these compounds may be markers not only of dietary exposure but also of metabolic effects of dietary exposure (Hanhineva et al. 2015).
Reduction of mussel metamorphosis by inactivation of the bacterial thioesterase gene via alteration of the fatty acid composition
Published in Biofouling, 2021
Xiao-Meng Hu, Junbo Zhang, Wen-Yang Ding, Xiao Liang, Rong Wan, Sergey Dobretsov, Jin-Long Yang
Table 1 presents the bacterial strains, plasmids, and primer sequences. Escherichia coli WM3064 (Dehio and Meyer 1997) obtained from Prof. Xiaoxue Wang was cultivated at 37 °C in LB medium (Sangon Biotech, Shanghai, China) supplemented with 2,6-diamino-pimelic acid at 0.3 mM for 4 h. Both wild-type and ΔtesA P. marina were cultivated in Zobell 2216E medium (Sigma, St Louis, MO, USA) at 25 °C, as previously described (Liang, Zhang et al. 2020). The antibiotics kanamycin and erythromycin (Sangon, Shanghai, China) were used to maintain pK18mobsacB-ery-based plasmids in E. coli (from Prof. Xiaoxue Wang) and P. marina (Zeng et al. 2015).
Microbial and metabolic features associated with outcome of infliximab therapy in pediatric Crohn’s disease
Published in Gut Microbes, 2021
Yizhong Wang, Xuefeng Gao, Xinyue Zhang, Fangfei Xiao, Hui Hu, Xiaolu Li, Fang Dong, Mingming Sun, Yongmei Xiao, Ting Ge, Dan Li, Guangjun Yu, Zhanju Liu, Ting Zhang
We further identified distinct fecal metabolome profiles between the pediatric CD patients with different therapeutic outcomes after IFX treatment (Figure 7d, e). Higher concentrations of glycine and L-lactic acid were found in the SR patients, whereas the NSR patients showed higher fecal levels of azelaic acid, N-acetylserotonin, sebacic acid, pimelic acid, isovaleric acid, nicotinic acid, adipic acid, and 4-aminohippuric acid (Figure 7f).
Recent trends in praziquantel nanoformulations for helminthiasis treatment
Published in Expert Opinion on Drug Delivery, 2022
Ana C. Mengarda, Bruno Iles, João Paulo F. Longo, Josué de Moraes
Finally, to improve biopharmaceutical properties of PZQ, Espinosa-Lara et al. 2013 [77] reported on nine new solid-state phases of PZQ in the form of cocrystals with malonic acid, oxalic acid, succinic acid (two polymorphic phases), fumaric acid, maleic acid, glutaric acid, pimelic acid, and adipic acid, that potentially present advantages over the drug in its actual commercially available presentations.