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Diet and IBS
Published in Melissa G. Hunt, Aaron T. Beck, Reclaim Your Life From IBS, 2022
Melissa G. Hunt, Aaron T. Beck
Ginger, like mint, has been used for millennia as a digestive aid, particularly for the treatment of nausea and vomiting. While nausea is not actually a symptom of IBS, some IBS patients do complain of nausea, and there is scientific evidence supporting its use as an anti-nausea remedy.15 Thus, there is data to suggest that ginger (taken fresh, drunk as tea, used as a spice in food, or taken as a supplement) may indeed reduce gastric (or stomach) distress, nausea, and vomiting. However, there are no scientific studies of the impact of ginger on IBS symptoms. Since IBS typically affects the intestines, not the stomach, ginger is unlikely to provide substantial relief to most people with IBS. But if you enjoy the flavor, feel free to use it as a spice or drink it in tea. It certainly won’t make your symptoms worse.
Spices as Eco-friendly Microbicides: From Kitchen to Clinic
Published in Mahendra Rai, Chistiane M. Feitosa, Eco-Friendly Biobased Products Used in Microbial Diseases, 2022
In traditional medicine, ginger is used to improve the flow of body fluids. It stimulates blood circulation throughout the body by powerful stimulatory effect on the heart muscles and by diluting blood. Essential oils from cumin, poppy, basil and rosemary components, carsinol, carnosol and urosolic acid possess anticarcinocenic activity.
Tropical Herbs and Spices as Functional Foods with Antidiabetic Activities
Published in Megh R. Goyal, Arijit Nath, Rasul Hafiz Ansar Suleria, Plant-Based Functional Foods and Phytochemicals, 2021
Arnia Sari Mukaromah, Fitria Susilowati
Ginger (Zingiber officinale Roscoe) is similar to turmeric and it is a popular ingredient in cooking due to a peculiar flavor, aroma, and pungent odors. Besides cooking, ginger is also well-known for its medicinal properties against gastrointestinal disorder, motion sickness, nausea relief, cold, and flu relief, pain, and inflammation (reduce muscle pain, knee, and elbow). Ginger contains several biochemical constituents, such as: gingerol, shogaol, paradol, and zingerone [23]. It may also reduce the risks of cardiovascular diseases (CVDs), blood clotting, and hyperglycemia.
Research progress on antiviral constituents in traditional Chinese medicines and their mechanisms of action
Published in Pharmaceutical Biology, 2022
The volatile oil of TCM is active to many kinds of viruses, especially enveloped viruses, such as herpes simplex virus, HIV virus, IFV virus and avian influenza virus (Ma and Yao 2020). Ginger has been used in Asia for centuries to ward off colds and colds because of its antiseptic and anti-inflammatory properties. In Europe, ginger is used for its digestive properties and its therapeutic effect on the digestive tract (Camero et al. 2019). The inhibitory effect of essential oil of ginger on RC-37 cells of herpes simplex virus type 2 (HSV-2) in vitro was screened by thrombocytopenia. The results showed that the effect of volatile oil on HSV-2 mainly occurred before the adsorption, possibly through the interaction with the viral envelope (Koch et al. 2008). The researchers tested the efficacy of peppermint essential oil derived from Mentha haplocalyx Briq. (Labiatae) aerial portion (Bohe) (EOMS) and its active principle piperitenone oxide (PEO) in vitro experimental model of infection with HSV-1. The results showed that the antiviral activity of the two compounds was mainly due to the effect of viral adsorption. Among them, PEO exerted a strong inhibitory effect by interfering with the late stage of HSV-1 life cycle. The compound may interfere with some REDOX sensitive cellular pathways involved in viral replication (Civitelli et al. 2014). These results suggest that EOs may be a potential therapeutic agent for the treatment of viral infections, as well as a prototype for new antiviral drug options, such as their proposed activity against SARS-CoV-2 virus (Asif et al. 2020).
A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Comparative Clinical Study to Evaluate the Efficacy and Safety of OLNP-06 versus Placebo in Subjects with Functional Dyspepsia
Published in Journal of Dietary Supplements, 2022
Sanjib Kumar Panda, MPharm, Somashekara Nirvanashetty, PhD, Vivek A. Parachur, BTech, Chakravarthy Krishnamoorthy, MPharm, Shemanti Dey, MSc
Ginger has been used as traditional medicine since time immemorial and has been shown to be useful in the treatment of FD (Anh et al. 2020). Many studies in animals have demonstrated that ginger rhizome extracts increase gastric emptying and gastrointestinal transit. A significant increase of the digestive motility after intervention with ginger extracts was observed. Wu et al. showed that ginger accelerates gastric emptying and stimulates antral contractions in healthy human volunteers (Wu et al. 2008). Animal emesis models likewise have shown reduced emesis with the administration of ginger. Nausea, vomiting and hypomotility involve a temporary dysfunction of the complex integrated network of cholinergic M3 and serotonergic 5-HT3/5-HT4 receptors in the body. In this respect, major chemical constituents of the ginger rhizome extracts, such as [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol have been shown in several experimental models to modulate these receptors with a differentiated potency. In particular, the capacity of ginger to reduce nausea and eventually vomiting seems to correlate with the effectiveness of these active ingredients to weakly inhibit M3 and 5-HT3 receptors. On the contrary, 5-HT4 receptors, which also play a role in gastroduodenal motility, do not seem to be involved in the effects of these compounds (Bouras et al. 2008; Vakil et al. 2008).
Gamma irradiations induced morphological and biochemical variations in in vitro regenerated ginger (Zingiber officinale rosc.)- an invaluable medicinal spice
Published in International Journal of Radiation Biology, 2021
The reduced dosage rate of radiation presumably caused non-significant harm to plant genetic material, allowing cells to self-repair. Abdullah et al. (2018) reported that irradiation dose higher than 10 Gy leads to gradual decrease in growth rate in ginger. Similarly, percent survival, plant height and number of shoots showed significant decline when in vitro shoots of ginger were treated with gamma irradiations more than 10 Gy (Sianipar et al. 2013). El-Khateeb et al. (2016) reported that survival percentage, plant height, stem diameter, leaf number per plant, leaf area, fresh weights and leaves/stem ratio decreased with the increased dose of gamma irradiations in Philodendron scandens whereas, lower doses of gamma irradiations does not showed significant differences for all the mentioned parameters with respect to control. Rashid et al. (2013) suggested that the dosage range for causing substantial alteration in ginger is between 10 and 25 Gy.