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Pharmacology and Therapeutics of Dandelion in Gastrointestinal Disorders
Published in Megh R. Goyal, Preeti Birwal, Durgesh Nandini Chauhan, Herbs, Spices, and Medicinal Plants for Human Gastrointestinal Disorders, 2023
Dandelion is a perennial herb with long roots and green rose-like arranged leaves. Persians were the first to recognize dandelion that was named as tarasque, around 900 A.D.18 Almost 100 years later, the name was changed into Taraxacum. The most common dandelion is Taraxacum officinale (TO).19 Normally, dandelion is characterized with around 20-cm long leaf, yellow, orange, or white color flower and stems or leaves with white milky latex.8
Nutraceutical Intervention for Treatment of Alcoholism and Drinking Problems
Published in Raj K. Keservani, Anil K. Sharma, Rajesh K. Kesharwani, Nutraceuticals and Dietary Supplements, 2020
Dandelion (Taraxacum officinale) belongs to the family Asteraceae and is a herbaceous perennial plant that possesses various medicinal and culinary uses. Dandelion has been used as a therapy for anemia, blood purification, and immunomodulation. The folk medicines of China, India, and Russia have recognized dandelion’s effect as a liver tonic. It is used conventionally for liver-related complications that justify its use in liquor drawing symptoms.
Catalog of Herbs
Published in James A. Duke, Handbook of Medicinal Herbs, 2018
Toxicity — According to “Jake’s Page”,315 “there is, experts aver, nothing toxic about a dandelion.”115 Contact sensitivity to this species has been reported. Mitchell and Rook6 dig up one old case from The Lancet 1881 (not seen): “Two patients who had ‘weed dermatitis’ showed positive patch test reactions to the plant; the patients were also contact sensitive to Chrysanthemum and Olearia.”6 I feel that it is a relatively safe herb, about to take over the world.
Development of dual-targeted nano-dandelion based on an oligomeric hyaluronic acid polymer targeting tumor-associated macrophages for combination therapy of non-small cell lung cancer
Published in Drug Delivery, 2019
Bingjie Wang, Wei Zhang, Xiudi Zhou, Mengna Liu, Xiaoya Hou, Ziting Cheng, Daquan Chen
In this study, quercetin–dithiodipropionic acid–oligomeric hyaluronic acid–mannose–ferulic acid (Que–S–S–oHA–Man–FA, QHMF) (Figure 1) was successfully synthesized to prepare Man/oHA-based nano-dandelion-like nano-micelles (NMs) for codelivery of Cur and Bai (Cur/Bai) targeting both A549 cells and TAMs. Specifically, on the one hand, nano-dandelion with oHA targeting CD44 receptors could facilitate uptake of nano-dandelion in tumor locations. On the other hand, nano-dandelion with Man could be easily engulfed by TAMs via specific binding of Man to CD206. S–S was used as truss arm to combine hydrophobic and hydrophilic parts, facilitating the release of Cur/Bai from nano-dandelion in the TME. Notably, an advantage of the nano-dandelion was synergistic treatment (combined chemotherapy and immunotherapy).
A qualitative research study comparing nutrition advice communicated by registered Dietitian and non-Registered Dietitian bloggers
Published in Journal of Communication in Healthcare, 2020
Taylor Chan, Teresa Drake, Rachel L. Vollmer
Non-RDs were advocates for alternative medicine and therapies, often discussing reasons conventional medicine is considered outdated or less effective by utilizing fear-based appeals to motivate people to take action. Exaggeration of outcomes using vivid imagery and dramatic adjectives, making immediate action seem necessary, were prevalent in non-RD blogs. Some common examples of the terminology used include ‘toxic,’ ‘dangerous,’ ‘addictive,’ ‘culprit,’ ‘damaging,’ and ‘death.’ Some bloggers encouraged alternative treatments as a replacement for conventional medicine, by recommending and referring to functional and holistic nutrition, food as a cure, herbal or micronutrient supplements and remedies, acupuncture, chiropractors, and massage therapy. While RD blogs tended to discuss macronutrients and food groups, non-RD blogs discussed foods in terms of the micronutrients they provide. Non-RD blogs shared micronutrient deficiencies, which could be resolved through eating particular foods, as well as supplementation. Some micronutrients of concern were magnesium, chromium, zinc, and selenium. In addition, herbal supplements, such as turmeric, milk thistle, and dandelion, were encouraged to help mitigate specific symptoms and diseases of concern. Bloggers provided non-specific symptom lists for readers to assess health status. Some common, non-specific symptoms included fatigue, headache, indigestion, weakness, and rashes. The presence of these symptoms was suggested to be indicative of several disease states, including hormone imbalance, liver toxicity, uncontrolled blood sugars, and thyroid or adrenal gland issues. Non-RD bloggers encouraged readers to resolve these conditions by incorporating specific combinations of food and supplements, while eliminating other foods that may aggravate symptoms.
Inhibitory effects of taraxasterol and aqueous extract of Taraxacum officinale on calcium oxalate crystallization: in vitro study
Published in Renal Failure, 2018
Mahboubeh Yousefi Ghale-Salimi, Maryam Eidi, Nasser Ghaemi, Ramezan Ali Khavari-Nejad
Dandelion aerial parts were collected from the Kashan area in the summer 2016 and were scientifically approved in the Department of Botany of Islamic Azad University (Voucher number: 047,643, deposited in I.A.U. Herbarium, identified by Prof. Ramezan Ali Khavari-Nejad). The dried aerial parts (300 g) were grounded (500 µm) and extracted three times (48 h) with distilled water (2500 mL), and filtered through a glass filter funnel. The extract was combined and the water was evaporated under reduced pressure by rotavapor, and the rest was mixed and homogenized [11,18].