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Published in Ken Addley, MCQs, MEQs and OSPEs in Occupational Medicine, 2023
Best fit. Hexavalent chromium salts are irritant, corrosive and carcinogenic. Nasal perforation is usually due to inhalation of chrome vapours (e.g., chrome plating tanks). Chromium compounds are sensitisers and may cause contact dermatitis and occupational asthma. Urinary chromium measurement at the end of shifts is routinely used to measure exposure in workers.
Inhalation Toxicity of Metal Particles and Vapors
Published in Jacob Loke, Pathophysiology and Treatment of Inhalation Injuries, 2020
Chromium compounds are used in tanning, pigments, and electroplating and as catalysts, corrosion inhibitors, and wood preservatives. Chromium metal is an essential ingredient of stainless steel, superalloys for jet engines, and other alloys.
Experimental Lung Carcinogenesis by Intratracheal Instillation
Published in Joan Gil, Models of Lung Disease, 2020
Although there is sufficient evidence for the carcinogenicity of calcium chromate and some relatively insoluble chromium compounds parenterally administered in rats, very few data are available for the carcinogenicity of IT-instilled or inhaled chromium (IARC, 1980). Recently, Steinhoff et al. (1986) found that sodium dichromate showed weak but significant lung carcinogenicity in rats after IT instillation.
Current Molecular and Genetic Aspects of Pancreatic Cancer, the Role of Metastasis Associated Proteins (MTA): A Review
Published in Journal of Investigative Surgery, 2018
Efstathios T. Pavlidis, Theodoros E. Pavlidis
Occupational and environmental factors have been implicated in cases of pancreatic cancer. They include exposure to smog, chlorinated hydrocarbons, nickel and nickel compounds, chromium compounds, polycyclic aromatic hydrocarbons, organochlorine insecticides, powered silicon dioxide, aliphatic solutions, asbestos, pesticides, radon, carbon products and radiation [40–42].